Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CNOT8
  • Mouse genes Cnot8
  • Rat genes Cnot8
  • Zfish genes cnot8
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cnot8

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0000175	3'-5'-RNA exonuclease activity	CNOT8	IDA		Human	PMID:15769875
Molecular Function	GO:0004535	poly(A)-specific ribonuclease activity	CNOT8	IDA		Human	PMID:15769875
Molecular Function	GO:0005515	protein binding	CNOT8	IPI	UniProtKB:A5YKK6	Human	PMID:10637334
Molecular Function	GO:0005515	protein binding	CNOT8	IPI	UniProtKB:O75175	Human	PMID:10637334
Molecular Function	GO:0005515	protein binding	CNOT8	IPI	UniProtKB:P62324	Human	PMID:11136725
Molecular Function	GO:0005515	protein binding	CNOT8	IPI	UniProtKB:P78543	Human	PMID:11136725
Molecular Function	GO:0005515	protein binding	CNOT8	IPI	UniProtKB:Q9ULM6	Human	PMID:11747467
Molecular Function	GO:0005515	protein binding	CNOT8	IPI	UniProtKB:P62324	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	CNOT8	IPI	UniProtKB:A5YKK6	Human	PMID:16778766
Molecular Function	GO:0005515	protein binding	CNOT8	IPI	UniProtKB:O75175	Human	PMID:16778766
Molecular Function	GO:0005515	protein binding	CNOT8	IPI	UniProtKB:Q9NZN8	Human	PMID:16778766
Molecular Function	GO:0005515	protein binding	CNOT8	IPI	UniProtKB:Q96LI5	Human	PMID:17452450
Molecular Function	GO:0005515	protein binding	CNOT8	IPI	UniProtKB:Q9ULM6	Human	PMID:17452450
Molecular Function	GO:0005515	protein binding	CNOT8	IPI	UniProtKB:P62324	Human	PMID:20211142
Molecular Function	GO:0005515	protein binding	CNOT8	IPI	UniProtKB:Q86TB9	Human	PMID:20584987
Molecular Function	GO:0005515	protein binding	CNOT8	IPI	UniProtKB:P22893	Human	PMID:20595389
Molecular Function	GO:0005515	protein binding	CNOT8	IPI	UniProtKB:P62324	Human	PMID:21900206
Molecular Function	GO:0005515	protein binding	CNOT8	IPI	UniProtKB:A5YKK6	Human	PMID:22977175
Molecular Function	GO:0005515	protein binding	CNOT8	IPI	UniProtKB:P78543	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CNOT8	IPI	UniProtKB:Q14106	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CNOT8	IPI	UniProtKB:Q6IBC8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CNOT8	IPI	UniProtKB:A5YKK6	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	CNOT8	IPI	UniProtKB:Q9NZN8	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	CNOT8	IPI	UniProtKB:P62324	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	CNOT8	IPI	UniProtKB:Q96LI5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Cnot8	IPI	UniProtKB:Q04211	Mouse	MGI:MGI:4455093|PMID:20211142
Molecular Function	GO:0005515	protein binding	Cnot8	IPI	UniProtKB:O70552	Mouse	MGI:MGI:5918927|PMID:27065194
Cellular Component	GO:0030014	CCR4-NOT complex	CNOT8	IDA		Human	PMID:19558367
Cellular Component	GO:0005634	nucleus	CNOT8	IDA		Human	PMID:9820826
Biological Process	GO:0043928	exonucleolytic catabolism of deadenylated mRNA	CNOT8	IDA		Human	PMID:20065043
Biological Process	GO:0048666	neuron development	cnot8	IGI	ZFIN:ZDB-GENO-150325-2	Zfish	PMID:25478689
Biological Process	GO:0048666	neuron development	cnot8	IMP	ZFIN:ZDB-GENO-150325-1	Zfish	PMID:25478689
Biological Process	GO:0008284	positive regulation of cell population proliferation	CNOT8	IMP		Human	PMID:19605561
Biological Process	GO:0061014	positive regulation of mRNA catabolic process	CNOT8	IMP		Human	PMID:22977175

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern