Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CLPB
  • Mouse genes Clpb
  • Rat genes Clpb
  • Zfish genes clpb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Clpb

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016887	ATP hydrolysis activity	CLPB	IMP		Human	PMID:34115842
Molecular Function	GO:0140545	ATP-dependent protein disaggregase activity	CLPB	IDA		Human	PMID:32573439
Molecular Function	GO:0140545	ATP-dependent protein disaggregase activity	CLPB	IMP		Human	PMID:34115842
Molecular Function	GO:0005515	protein binding	CLPB	IPI	UniProtKB:Q8NHQ1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CLPB	IPI	UniProtKB:P35232|UniProtKB:Q7Z434|UniProtKB:Q92667|UniProtKB:Q99623|UniProtKB:Q9NVI7	Human	PMID:31522117
Cellular Component	GO:0005758	mitochondrial intermembrane space	CLPB	IDA		Human	PMID:31522117
Cellular Component	GO:0005758	mitochondrial intermembrane space	CLPB	IMP		Human	PMID:34115842
Cellular Component	GO:0005739	mitochondrion	Clpb	HDA		Mouse	PMID:18614015
Biological Process	GO:0140374	antiviral innate immune response	CLPB	IDA		Human	PMID:31522117
Biological Process	GO:0034605	cellular response to heat	CLPB	IDA		Human	PMID:2745427
Biological Process	GO:0021549	cerebellum development	clpb	IMP	ZFIN:ZDB-MRPHLNO-150429-1	Zfish	PMID:25597510
Biological Process	GO:0030851	granulocyte differentiation	CLPB	IMP		Human	PMID:34115842
Biological Process	GO:0030851	granulocyte differentiation	CLPB	IMP		Human	PMID:34140661
Biological Process	GO:0060322	head development	clpb	IMP	ZFIN:ZDB-MRPHLNO-150529-4	Zfish	PMID:25650066
Biological Process	GO:0039529	RIG-I signaling pathway	CLPB	IDA		Human	PMID:31522117
Biological Process	GO:0001966	thigmotaxis	clpb	IMP	ZFIN:ZDB-MRPHLNO-150529-4	Zfish	PMID:25650066

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern