Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CHTOP
  • Mouse genes Chtop
  • Rat genes Chtop,Chtopl1
  • Zfish genes chtopa,chtopb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Chtop

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008327	methyl-CpG binding	CHTOP	IDA		Human	PMID:25284789
Molecular Function	GO:0005515	protein binding	CHTOP	IPI	UniProtKB:Q13838	Human	PMID:14667819
Molecular Function	GO:0005515	protein binding	CHTOP	IPI	UniProtKB:Q99873	Human	PMID:19858291
Molecular Function	GO:0005515	protein binding	CHTOP	IPI	UniProtKB:Q13838	Human	PMID:23299939
Molecular Function	GO:0005515	protein binding	CHTOP	IPI	UniProtKB:Q86V81	Human	PMID:23299939
Molecular Function	GO:0005515	protein binding	CHTOP	IPI	UniProtKB:Q9UBU9	Human	PMID:23299939
Molecular Function	GO:0005515	protein binding	CHTOP	IPI	UniProtKB:P78362	Human	PMID:23602568
Molecular Function	GO:0005515	protein binding	CHTOP	IPI	UniProtKB:O14744	Human	PMID:25284789
Molecular Function	GO:0005515	protein binding	CHTOP	IPI	UniProtKB:P84090	Human	PMID:25284789
Molecular Function	GO:0005515	protein binding	CHTOP	IPI	UniProtKB:Q99873	Human	PMID:25284789
Molecular Function	GO:0005515	protein binding	CHTOP	IPI	UniProtKB:Q9BQA1	Human	PMID:25284789
Molecular Function	GO:0005515	protein binding	CHTOP	IPI	UniProtKB:P84090	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CHTOP	IPI	UniProtKB:Q16637	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CHTOP	IPI	UniProtKB:Q5VWX1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CHTOP	IPI	UniProtKB:P84090	Human	PMID:30021884
Molecular Function	GO:0005515	protein binding	CHTOP	IPI	UniProtKB:Q13838	Human	PMID:30021884
Molecular Function	GO:0005515	protein binding	CHTOP	IPI	UniProtKB:P78362	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	Chtop	IPI	UniProtKB:Q9JIF0	Mouse	MGI:MGI:4420157|PMID:19858291
Molecular Function	GO:0005515	protein binding	Chtop	IPI	UniProtKB:Q8CIG8	Mouse	MGI:MGI:4420157|PMID:19858291
Molecular Function	GO:0003723	RNA binding	CHTOP	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	CHTOP	HDA		Human	PMID:22681889
Cellular Component	GO:0016607	nuclear speck	CHTOP	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016607	nuclear speck	CHTOP	IDA		Human	PMID:23299939
Cellular Component	GO:0000346	transcription export complex	CHTOP	IDA		Human	PMID:23299939
Biological Process	GO:0001701	in utero embryonic development	Chtop	IMP	MGI:MGI:4842477	Mouse	PMID:27996060
Biological Process	GO:0006406	mRNA export from nucleus	CHTOP	IDA		Human	PMID:23299939
Biological Process	GO:0032781	positive regulation of ATP-dependent activity	CHTOP	IDA		Human	PMID:23299939
Biological Process	GO:0008284	positive regulation of cell population proliferation	CHTOP	IMP		Human	PMID:25284789
Biological Process	GO:0051096	positive regulation of helicase activity	CHTOP	IDA		Human	PMID:23299939
Biological Process	GO:0031062	positive regulation of histone methylation	CHTOP	IMP		Human	PMID:25284789

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern