Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CDK5RAP1
  • Mouse genes Cdk5rap1
  • Rat genes Cdk5rap1
  • Zfish genes cdk5rap1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cdk5rap1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0035597	N6-isopentenyladenosine methylthiotransferase activity	Cdk5rap1	IMP	MGI:MGI:5750452	Mouse	PMID:25738458
Molecular Function	GO:0044877	protein-containing complex binding	Cdk5rap1	IDA		Rat	PMID:10721722|RGD:632478
Cellular Component	GO:0005829	cytosol	CDK5RAP1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	CDK5RAP1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	Cdk5rap1	IMP	MGI:MGI:5750452	Mouse	MGI:MGI:5635958|PMID:25738458
Cellular Component	GO:0005739	mitochondrion	Cdk5rap1	IDA		Mouse	PMID:25738458
Cellular Component	GO:0005654	nucleoplasm	CDK5RAP1	IDA		Human	GO_REF:0000052
Biological Process	GO:0070900	mitochondrial tRNA modification	Cdk5rap1	IMP	MGI:MGI:5750452	Mouse	PMID:25738458
Biological Process	GO:0045736	negative regulation of cyclin-dependent protein serine/threonine kinase activity	CDK5RAP1	IDA		Human	PMID:11882646
Biological Process	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity	Cdk5rap1	IDA		Rat	PMID:10721722|RGD:632478
Biological Process	GO:0070131	positive regulation of mitochondrial translation	Cdk5rap1	IMP	MGI:MGI:5750452	Mouse	PMID:25738458
Biological Process	GO:0045903	positive regulation of translational fidelity	Cdk5rap1	IGI	NCBI_Gene:945260	Mouse	PMID:25738458
Biological Process	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity	Cdk5rap1	IDA		Rat	PMID:10721722|RGD:632478

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern