Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CDC45
  • Mouse genes Cdc45
  • Rat genes Cdc45
  • Zfish genes cdc45
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cdc45

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	CDC45	IPI	UniProtKB:P09884	Human	PMID:10518787
Molecular Function	GO:0005515	protein binding	CDC45	IPI	UniProtKB:P38936	Human	PMID:15232106
Molecular Function	GO:0005515	protein binding	CDC45	IPI	UniProtKB:Q92547	Human	PMID:17887956
Molecular Function	GO:0005515	protein binding	CDC45	IPI	UniProtKB:P49736	Human	PMID:19805216
Molecular Function	GO:0005515	protein binding	CDC45	IPI	UniProtKB:P15927	Human	PMID:23910567
Molecular Function	GO:0005515	protein binding	CDC45	IPI	UniProtKB:Q9HAW4	Human	PMID:23910567
Molecular Function	GO:0005515	protein binding	CDC45	IPI	UniProtKB:P38936	Human	PMID:25241761
Molecular Function	GO:0005515	protein binding	CDC45	IPI	UniProtKB:Q53EZ4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CDC45	IPI	UniProtKB:P49736	Human	PMID:26167883
Molecular Function	GO:0005515	protein binding	CDC45	IPI	UniProtKB:Q53EZ4	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	CDC45	IPI	UniProtKB:P61018	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDC45	IPI	UniProtKB:Q53EZ4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDC45	IPI	UniProtKB:Q96D03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDC45	IPI	UniProtKB:Q9UGI0	Human	PMID:32296183
Cellular Component	GO:0005813	centrosome	CDC45	IDA		Human	GO_REF:0000052
Cellular Component	GO:0036064	ciliary basal body	CDC45	IDA		Human	PMID:29257953
Cellular Component	GO:0071162	CMG complex	CDC45	IPI		Human	PMID:22474384
Cellular Component	GO:0005654	nucleoplasm	CDC45	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	CDC45	IDA		Human	PMID:21383955
Cellular Component	GO:0005634	nucleus	CDC45	IDA		Human	PMID:22474384
Biological Process	GO:0006268	DNA unwinding involved in DNA replication	CDC45	IDA		Human	PMID:22474384

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern