Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CD177
  • Mouse genes Cd177
  • Rat genes Cd177
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cd177

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0048306	calcium-dependent protein binding	CD177	IPI	UniProtKB:P16284	Human	PMID:17580308
Molecular Function	GO:0005178	integrin binding	CD177	IPI	UniProtKB:P05107,UniProtKB:P11215	Human	PMID:21193407
Molecular Function	GO:0005178	integrin binding	CD177	IPI	UniProtKB:P05107	Human	PMID:28807980
Molecular Function	GO:0002020	protease binding	CD177	IPI	UniProtKB:P24158	Human	PMID:17244676
Molecular Function	GO:0002020	protease binding	CD177	IPI	UniProtKB:P24158	Human	PMID:28240246
Molecular Function	GO:0005515	protein binding	CD177	IPI	UniProtKB:Q9Y2W7	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	CD177	IPI	UniProtKB:Q9Y2W7	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CD177	IPI	UniProtKB:Q9Y2W7	Human	PMID:32296183
Cellular Component	GO:0070062	extracellular exosome	CD177	HDA		Human	PMID:23533145
Cellular Component	GO:0005886	plasma membrane	CD177	IDA		Human	PMID:12675722
Cellular Component	GO:0005886	plasma membrane	CD177	IDA		Human	PMID:17244676
Cellular Component	GO:0005886	plasma membrane	CD177	IDA		Human	PMID:18462208
Cellular Component	GO:0005886	plasma membrane	CD177	IDA		Human	PMID:21193407
Cellular Component	GO:0005886	plasma membrane	CD177	IDA		Human	PMID:22266279
Cellular Component	GO:0005886	plasma membrane	CD177	IDA		Human	PMID:23461681
Cellular Component	GO:0005886	plasma membrane	CD177	IDA		Human	PMID:24926686
Cellular Component	GO:0005886	plasma membrane	CD177	IDA		Human	PMID:27227454
Cellular Component	GO:0005886	plasma membrane	CD177	IDA		Human	PMID:28240246
Cellular Component	GO:0005886	plasma membrane	CD177	IDA		Human	PMID:28807980
Cellular Component	GO:0044853	plasma membrane raft	CD177	IDA		Human	PMID:21193407
Cellular Component	GO:0030667	secretory granule membrane	CD177	IDA		Human	PMID:18462208
Cellular Component	GO:0070821	tertiary granule membrane	CD177	IDA		Human	PMID:18462208
Biological Process	GO:0007155	cell adhesion	CD177	IMP		Human	PMID:28807980
Biological Process	GO:0098742	cell-cell adhesion via plasma-membrane adhesion molecules	CD177	IMP		Human	PMID:17580308
Biological Process	GO:0045217	cell-cell junction maintenance	CD177	IMP		Human	PMID:23202369
Biological Process	GO:0007159	leukocyte cell-cell adhesion	CD177	IMP		Human	PMID:17580308
Biological Process	GO:0072672	neutrophil extravasation	CD177	IMP		Human	PMID:17580308
Biological Process	GO:0072672	neutrophil extravasation	CD177	IMP		Human	PMID:22266279
Biological Process	GO:1990266	neutrophil migration	CD177	IMP		Human	PMID:28807980
Biological Process	GO:0043315	positive regulation of neutrophil degranulation	CD177	IGI	UniProtKB:P05107,UniProtKB:P11215	Human	PMID:21193407
Biological Process	GO:0032930	positive regulation of superoxide anion generation	CD177	IGI	UniProtKB:P05107,UniProtKB:P11215	Human	PMID:21193407
Biological Process	GO:0034394	protein localization to cell surface	CD177	IMP		Human	PMID:17244676
Biological Process	GO:0034394	protein localization to cell surface	CD177	IMP		Human	PMID:18462208
Biological Process	GO:0030100	regulation of endocytosis	CD177	IDA		Human	PMID:28807980
Biological Process	GO:2001044	regulation of integrin-mediated signaling pathway	CD177	IMP		Human	PMID:28807980

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern