Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CCM2L
  • Mouse genes Ccm2l
  • Rat genes Ccm2l
  • Zfish genes ccm2l
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ccm2l

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	CCM2L	IPI	UniProtKB:P20618	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCM2L	IPI	UniProtKB:Q13554-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCM2L	IPI	UniProtKB:Q9BYU1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCM2L	IPI	UniProtKB:Q9NZ43	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Ccm2l	IPI	PR:Q6S5J6	Mouse	PMID:22898778
Molecular Function	GO:0005515	protein binding	Ccm2l	IPI	PR:E9Q7X6	Mouse	PMID:22898778
Biological Process	GO:0009948	anterior/posterior axis specification	ccm2l	IGI	ZFIN:ZDB-GENO-160218-8,ZFIN:ZDB-MRPHLNO-160205-1	Zfish	PMID:26540726
Biological Process	GO:0009948	anterior/posterior axis specification	ccm2l	IGI	ZFIN:ZDB-MRPHLNO-160205-1,ZFIN:ZDB-MRPHLNO-160205-3	Zfish	PMID:26540726
Biological Process	GO:0009948	anterior/posterior axis specification	ccm2l	IGI	ZFIN:ZDB-GENO-160218-8,ZFIN:ZDB-MRPHLNO-160205-1,ZFIN:ZDB-MRPHLNO-160205-3	Zfish	PMID:26540726
Biological Process	GO:0009948	anterior/posterior axis specification	ccm2l	IGI	ZFIN:ZDB-GENO-160218-9,ZFIN:ZDB-MRPHLNO-160205-1	Zfish	PMID:26540726
Biological Process	GO:0003209	cardiac atrium morphogenesis	Ccm2l	IGI	MGI:MGI:1924696	Mouse	PMID:22898778
Biological Process	GO:0055017	cardiac muscle tissue growth	Ccm2l	IGI	MGI:MGI:1924696	Mouse	PMID:22898778
Biological Process	GO:0090269	fibroblast growth factor production	Ccm2l	IGI	MGI:MGI:1924696	Mouse	PMID:22898778
Biological Process	GO:0060047	heart contraction	ccm2l	IGI	ZFIN:ZDB-GENO-160218-8,ZFIN:ZDB-MRPHLNO-160205-1	Zfish	PMID:26540726
Biological Process	GO:0060047	heart contraction	ccm2l	IGI	ZFIN:ZDB-GENO-160218-9,ZFIN:ZDB-MRPHLNO-160205-1	Zfish	PMID:26540726
Biological Process	GO:0007507	heart development	ccm2l	IMP	ZFIN:ZDB-MRPHLNO-160205-1	Zfish	PMID:26540726
Biological Process	GO:0007507	heart development	ccm2l	IGI	ZFIN:ZDB-GENO-160218-9,ZFIN:ZDB-MRPHLNO-160205-1	Zfish	PMID:26540726
Biological Process	GO:0007507	heart development	ccm2l	IGI	ZFIN:ZDB-GENO-160218-8,ZFIN:ZDB-MRPHLNO-160205-1	Zfish	PMID:26540726
Biological Process	GO:0007507	heart development	ccm2l	IGI	ZFIN:ZDB-GENO-160218-8,ZFIN:ZDB-MRPHLNO-160205-1,ZFIN:ZDB-MRPHLNO-160205-3	Zfish	PMID:26540726
Biological Process	GO:0007507	heart development	ccm2l	IGI	ZFIN:ZDB-MRPHLNO-160205-1,ZFIN:ZDB-MRPHLNO-160205-3	Zfish	PMID:26540726
Biological Process	GO:0007507	heart development	ccm2l	IMP	ZFIN:ZDB-MRPHLNO-160205-2	Zfish	PMID:26540726
Biological Process	GO:0003007	heart morphogenesis	ccm2l	IGI	ZFIN:ZDB-MRPHLNO-060821-1,ZFIN:ZDB-MRPHLNO-130531-2	Zfish	PMID:23328253
Biological Process	GO:0003007	heart morphogenesis	ccm2l	IMP	ZFIN:ZDB-MRPHLNO-130531-1	Zfish	PMID:23328253
Biological Process	GO:0003007	heart morphogenesis	ccm2l	IMP	ZFIN:ZDB-MRPHLNO-130531-2	Zfish	PMID:23328253
Biological Process	GO:0003007	heart morphogenesis	ccm2l	IGI	ZFIN:ZDB-MRPHLNO-060821-1,ZFIN:ZDB-MRPHLNO-130531-1	Zfish	PMID:23328253
Biological Process	GO:0034109	homotypic cell-cell adhesion	Ccm2l	IDA		Mouse	PMID:22898778
Biological Process	GO:0034111	negative regulation of homotypic cell-cell adhesion	Ccm2l	IDA		Mouse	PMID:22898778
Biological Process	GO:0032091	negative regulation of protein binding	Ccm2l	IDA		Mouse	PMID:22898778
Biological Process	GO:0090271	positive regulation of fibroblast growth factor production	Ccm2l	IGI	MGI:MGI:1924696	Mouse	PMID:22898778
Biological Process	GO:0003222	ventricular trabecula myocardium morphogenesis	Ccm2l	IGI	MGI:MGI:1924696	Mouse	PMID:22898778
Biological Process	GO:0042060	wound healing	Ccm2l	IMP	MGI:MGI:5439489	Mouse	PMID:22898778

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern