Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CBR4
  • Mouse genes Cbr4
  • Rat genes Cbr4
  • Zfish genes cbr4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cbr4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004316	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity	CBR4	IDA		Human	PMID:19571038
Molecular Function	GO:0004316	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity	CBR4	IMP	UniProtKB:Q92506	Human	PMID:25203508
Molecular Function	GO:0003955	NAD(P)H dehydrogenase (quinone) activity	CBR4	IDA		Human	PMID:20837989
Molecular Function	GO:0070402	NADPH binding	CBR4	IDA		Human	PMID:19000905
Molecular Function	GO:0070402	NADPH binding	CBR4	IDA		Human	PMID:25203508
Molecular Function	GO:0008753	NADPH dehydrogenase (quinone) activity	CBR4	IDA		Human	PMID:19000905
Molecular Function	GO:0005515	protein binding	CBR4	IPI	UniProtKB:Q92506	Human	PMID:19571038
Molecular Function	GO:0005515	protein binding	CBR4	IPI	UniProtKB:Q92506	Human	PMID:25203508
Molecular Function	GO:0005515	protein binding	CBR4	IPI	UniProtKB:Q2QGD7	Human	PMID:32296183
Molecular Function	GO:0048038	quinone binding	CBR4	IDA		Human	PMID:19000905
Cellular Component	GO:0005759	mitochondrial matrix	CBR4	IDA		Human	PMID:19000905
Cellular Component	GO:0005759	mitochondrial matrix	CBR4	IDA		Human	PMID:19571038
Cellular Component	GO:0005739	mitochondrion	Cbr4	HDA		Mouse	PMID:18614015
Cellular Component	GO:1990204	oxidoreductase complex	CBR4	IDA		Human	PMID:19571038
Cellular Component	GO:1990204	oxidoreductase complex	CBR4	IMP		Human	PMID:25203508
Biological Process	GO:0044597	daunorubicin metabolic process	CBR4	IMP		Human	PMID:20837989
Biological Process	GO:0044598	doxorubicin metabolic process	CBR4	IMP		Human	PMID:20837989
Biological Process	GO:0006633	fatty acid biosynthetic process	CBR4	IMP	UniProtKB:Q92506	Human	PMID:25203508
Biological Process	GO:0051290	protein heterotetramerization	CBR4	IDA		Human	PMID:25203508
Biological Process	GO:0051289	protein homotetramerization	CBR4	IDA		Human	PMID:19000905

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern