Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CA1
  • Mouse genes Car1
  • Rat genes Car1
  • Zfish genes ca2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Car1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004064	arylesterase activity	CA1	IMP		Human	PMID:7758465
Molecular Function	GO:0004089	carbonate dehydratase activity	CA1	IMP		Human	PMID:7758465
Molecular Function	GO:0004089	carbonate dehydratase activity	ca2	IMP	ZFIN:ZDB-MRPHLNO-100517-6	Zfish	PMID:19915126
Molecular Function	GO:0004089	carbonate dehydratase activity	ca2	IGI	ZFIN:ZDB-MRPHLNO-100517-5,ZFIN:ZDB-MRPHLNO-100517-6	Zfish	PMID:19915126
Molecular Function	GO:0016836	hydro-lyase activity	CA1	IDA		Human	PMID:2114290
Molecular Function	GO:0005515	protein binding	CA1	IPI	UniProtKB:Q12800	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CA1	IPI	UniProtKB:Q12800	Human	PMID:25910212
Cellular Component	GO:0070062	extracellular exosome	CA1	HDA		Human	PMID:23533145
Biological Process	GO:0015670	carbon dioxide transport	ca2	IMP	ZFIN:ZDB-MRPHLNO-100517-6	Zfish	PMID:19915126
Biological Process	GO:0015670	carbon dioxide transport	ca2	IGI	ZFIN:ZDB-MRPHLNO-100517-5,ZFIN:ZDB-MRPHLNO-100517-6	Zfish	PMID:19915126
Biological Process	GO:0071466	cellular response to xenobiotic stimulus	ca2	IDA		Zfish	PMID:18618001
Biological Process	GO:0042539	hypotonic salinity response	ca2	IDA		Zfish	PMID:17299134
Biological Process	GO:0006885	regulation of pH	ca2	IMP	ZFIN:ZDB-MRPHLNO-080923-3	Zfish	PMID:18322140
Biological Process	GO:0098719	sodium ion import across plasma membrane	ca2	IMP	ZFIN:ZDB-MRPHLNO-130611-3	Zfish	PMID:23565095
Biological Process	GO:0006814	sodium ion transport	ca2	IMP	ZFIN:ZDB-MRPHLNO-080923-3	Zfish	PMID:18322140

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern