Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CACNA2D2
  • Mouse genes Cacna2d2
  • Rat genes Cacna2d2
  • Zfish genes cacna2d2a,cacna2d2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cacna2d2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005245	voltage-gated calcium channel activity	Cacna2d2	IDA		Mouse	PMID:11487633
Molecular Function	GO:0005245	voltage-gated calcium channel activity	Cacna2d2	IDA		Rat	PMID:12606261|RGD:632381
Cellular Component	GO:0005891	voltage-gated calcium channel complex	Cacna2d2	IDA		Mouse	PMID:11487633
Biological Process	GO:0006816	calcium ion transport	Cacna2d2	IDA		Rat	PMID:12606261|RGD:632381
Biological Process	GO:0055001	muscle cell development	Cacna2d2	IMP	MGI:MGI:1856022	Mouse	PMID:17320843
Biological Process	GO:0007528	neuromuscular junction development	Cacna2d2	IMP	MGI:MGI:1856022	Mouse	PMID:17320843
Biological Process	GO:0035265	organ growth	Cacna2d2	IMP	MGI:MGI:1856022	Mouse	PMID:9349522
Biological Process	GO:0046622	positive regulation of organ growth	Cacna2d2	IMP	MGI:MGI:1856022	Mouse	PMID:9349522
Biological Process	GO:0008016	regulation of heart contraction	Cacna2d2	IMP		Rat	PMID:28469787|RGD:13513983
Biological Process	GO:0040014	regulation of multicellular organism growth	Cacna2d2	IMP	MGI:MGI:1856022	Mouse	PMID:17320843
Biological Process	GO:0060024	rhythmic synaptic transmission	Cacna2d2	IMP	MGI:MGI:1856022	Mouse	PMID:16474392

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern