Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes BIN2
  • Mouse genes Bin2
  • Rat genes Bin2
  • Zfish genes bin2a,bin2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Bin2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005543	phospholipid binding	BIN2	IDA		Human	PMID:23285027
Molecular Function	GO:0005515	protein binding	BIN2	IPI	UniProtKB:O00499	Human	PMID:10903846
Molecular Function	GO:0005515	protein binding	BIN2	IPI	UniProtKB:Q8TB24	Human	PMID:23185384
Molecular Function	GO:0005515	protein binding	BIN2	IPI	UniProtKB:Q92624	Human	PMID:32296183
Cellular Component	GO:0001891	phagocytic cup	BIN2	IDA		Human	PMID:23285027
Cellular Component	GO:0005886	plasma membrane	BIN2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0002102	podosome	BIN2	IDA		Human	PMID:23285027
Biological Process	GO:0060326	cell chemotaxis	BIN2	IMP		Human	PMID:23285027
Biological Process	GO:0006911	phagocytosis, engulfment	BIN2	IMP		Human	PMID:23285027
Biological Process	GO:0097320	plasma membrane tubulation	BIN2	IDA		Human	PMID:23285027
Biological Process	GO:0071800	podosome assembly	BIN2	IMP		Human	PMID:23285027

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern