Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes BCKDK
  • Mouse genes Bckdk
  • Rat genes Bckdk
  • Zfish genes bckdk
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Bckdk

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0047323	[3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity	Bckdk	IMP		Rat	PMID:1377677|RGD:68712
Molecular Function	GO:0047323	[3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity	Bckdk	IMP		Rat	PMID:7649998|RGD:69775
Molecular Function	GO:0005524	ATP binding	Bckdk	IDA		Rat	PMID:1377677|RGD:68712
Molecular Function	GO:0005515	protein binding	BCKDK	IPI	UniProtKB:Q9WMX2:PRO_0000037548	Human	PMID:18985028
Molecular Function	GO:0005515	protein binding	BCKDK	IPI	UniProtKB:P40763	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	BCKDK	IPI	UniProtKB:P02549	Human	PMID:32296183
Molecular Function	GO:0004672	protein kinase activity	Bckdk	IDA		Mouse	PMID:9611264
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Bckdk	IDA		Rat	PMID:1377677|RGD:68712
Cellular Component	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex	Bckdk	IDA		Rat	PMID:1377677|RGD:68712
Cellular Component	GO:0005739	mitochondrion	BCKDK	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	BCKDK	HDA		Human	PMID:20833797
Cellular Component	GO:0005739	mitochondrion	Bckdk	HDA		Mouse	PMID:14651853
Cellular Component	GO:0005739	mitochondrion	Bckdk	HDA		Mouse	PMID:18614015
Biological Process	GO:0009083	branched-chain amino acid catabolic process	Bckdk	IDA		Rat	PMID:1377677|RGD:68712
Biological Process	GO:0006550	isoleucine catabolic process	Bckdk	IMP		Rat	PMID:27472223|RGD:39131293
Biological Process	GO:0006552	leucine catabolic process	Bckdk	IMP		Rat	PMID:27472223|RGD:39131293
Biological Process	GO:0016310	phosphorylation	Bckdk	IDA		Rat	PMID:1377677|RGD:68712
Biological Process	GO:0007283	spermatogenesis	Bckdk	IMP		Rat	PMID:27472223|RGD:39131293
Biological Process	GO:0006574	valine catabolic process	Bckdk	IMP		Rat	PMID:27472223|RGD:39131293

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern