Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes BCAT2
  • Mouse genes Bcat2
  • Rat genes Bcat2
  • Zfish genes bcat2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Bcat2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004084	branched-chain-amino-acid transaminase activity	Bcat2	IDA		Mouse	PMID:14755340
Molecular Function	GO:0004084	branched-chain-amino-acid transaminase activity	Bcat2	IDA		Rat	PMID:11733007|RGD:1582175
Molecular Function	GO:0004084	branched-chain-amino-acid transaminase activity	Bcat2	IDA		Rat	PMID:9165094|RGD:67954
Molecular Function	GO:0052656	L-isoleucine transaminase activity	BCAT2	IDA		Human	PMID:8702755
Molecular Function	GO:0052654	L-leucine transaminase activity	BCAT2	IDA		Human	PMID:8702755
Molecular Function	GO:0052655	L-valine transaminase activity	BCAT2	IDA		Human	PMID:8702755
Cellular Component	GO:0005737	cytoplasm	Bcat2	IDA		Rat	PMID:11733007|RGD:1582175
Cellular Component	GO:0005739	mitochondrion	BCAT2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	Bcat2	HDA		Mouse	PMID:14651853
Cellular Component	GO:0005739	mitochondrion	Bcat2	IDA		Mouse	PMID:14755340
Cellular Component	GO:0005739	mitochondrion	Bcat2	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005739	mitochondrion	Bcat2	IDA		Rat	PMID:11733007|RGD:1582175
Cellular Component	GO:0005739	mitochondrion	Bcat2	IDA		Rat	PMID:9165094|RGD:67954
Cellular Component	GO:0005654	nucleoplasm	BCAT2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Bcat2	IDA		Rat	PMID:11733007|RGD:1582175
Biological Process	GO:0009083	branched-chain amino acid catabolic process	Bcat2	IMP	MGI:MGI:3028726	Mouse	PMID:14755340
Biological Process	GO:0009083	branched-chain amino acid catabolic process	Bcat2	IDA		Rat	PMID:11733007|RGD:1582175
Biological Process	GO:0009081	branched-chain amino acid metabolic process	Bcat2	IMP	MGI:MGI:3772355	Mouse	PMID:20237068
Biological Process	GO:1990830	cellular response to leukemia inhibitory factor	Bcat2	IEP		Mouse	PMID:20439489
Biological Process	GO:0006550	isoleucine catabolic process	Bcat2	IMP	MGI:MGI:3772355	Mouse	PMID:17767905
Biological Process	GO:0006550	isoleucine catabolic process	Bcat2	IDA		Rat	PMID:11733007|RGD:1582175
Biological Process	GO:0006549	isoleucine metabolic process	Bcat2	IMP	MGI:MGI:3028726	Mouse	PMID:14755340
Biological Process	GO:0007595	lactation	Bcat2	IEP		Rat	PMID:11171603|RGD:62398
Biological Process	GO:0007595	lactation	Bcat2	IEP		Rat	PMID:11787736|RGD:1599445
Biological Process	GO:0009098	leucine biosynthetic process	Bcat2	IDA		Rat	PMID:11733007|RGD:1582175
Biological Process	GO:0006551	leucine metabolic process	Bcat2	IMP	MGI:MGI:3772355	Mouse	PMID:17767905
Biological Process	GO:0006551	leucine metabolic process	Bcat2	IMP	MGI:MGI:3028726	Mouse	PMID:14755340
Biological Process	GO:0010817	regulation of hormone levels	Bcat2	IMP	MGI:MGI:3772355	Mouse	PMID:17767905
Biological Process	GO:0006573	valine metabolic process	Bcat2	IMP	MGI:MGI:3028726	Mouse	PMID:14755340
Biological Process	GO:0006573	valine metabolic process	Bcat2	IMP	MGI:MGI:3772355	Mouse	PMID:17767905

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern