Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes APTX
  • Mouse genes Aptx
  • Rat genes Aptx
  • Zfish genes aptx
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Aptx

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	APTX	IDA		Human	PMID:15044383
Molecular Function	GO:0003684	damaged DNA binding	APTX	IDA		Human	PMID:14755728
Molecular Function	GO:0033699	DNA 5'-adenosine monophosphate hydrolase activity	APTX	IDA		Human	PMID:16547001
Molecular Function	GO:0033699	DNA 5'-adenosine monophosphate hydrolase activity	APTX	IDA		Human	PMID:16964241
Molecular Function	GO:0033699	DNA 5'-adenosine monophosphate hydrolase activity	APTX	IDA		Human	PMID:17276982
Molecular Function	GO:0033699	DNA 5'-adenosine monophosphate hydrolase activity	APTX	IDA		Human	PMID:17519253
Molecular Function	GO:0033699	DNA 5'-adenosine monophosphate hydrolase activity	Aptx	IMP		Mouse	MGI:MGI:3665365|PMID:16964241
Molecular Function	GO:0003690	double-stranded DNA binding	APTX	IDA		Human	PMID:16547001
Molecular Function	GO:0003690	double-stranded DNA binding	APTX	IDA		Human	PMID:17276982
Molecular Function	GO:0003725	double-stranded RNA binding	APTX	IDA		Human	PMID:16547001
Molecular Function	GO:0008967	phosphoglycolate phosphatase activity	APTX	IDA		Human	PMID:17519253
Molecular Function	GO:0051219	phosphoprotein binding	APTX	IPI	UniProtKB:Q14676	Human	PMID:20008512
Molecular Function	GO:0005515	protein binding	APTX	IPI	UniProtKB:P18887	Human	PMID:14755728
Molecular Function	GO:0005515	protein binding	APTX	IPI	UniProtKB:P04637	Human	PMID:15044383
Molecular Function	GO:0005515	protein binding	APTX	IPI	UniProtKB:P09874	Human	PMID:15044383
Molecular Function	GO:0005515	protein binding	APTX	IPI	UniProtKB:P18887	Human	PMID:15044383
Molecular Function	GO:0005515	protein binding	APTX	IPI	UniProtKB:P18887	Human	PMID:15380105
Molecular Function	GO:0005515	protein binding	APTX	IPI	UniProtKB:Q13426	Human	PMID:15380105
Molecular Function	GO:0005515	protein binding	APTX	IPI	UniProtKB:P09874	Human	PMID:15555565
Molecular Function	GO:0005515	protein binding	APTX	IPI	UniProtKB:P18887	Human	PMID:15555565
Molecular Function	GO:0005515	protein binding	APTX	IPI	UniProtKB:Q13426	Human	PMID:16439205
Molecular Function	GO:0005515	protein binding	APTX	IPI	UniProtKB:P18887	Human	PMID:16713569
Molecular Function	GO:0005515	protein binding	APTX	IPI	UniProtKB:Q13426	Human	PMID:16713569
Molecular Function	GO:0005515	protein binding	APTX	IPI	UniProtKB:P17480	Human	PMID:16777843
Molecular Function	GO:0005515	protein binding	APTX	IPI	UniProtKB:P19338	Human	PMID:16777843
Molecular Function	GO:0005515	protein binding	APTX	IPI	UniProtKB:Q8ND90	Human	PMID:25416956
Cellular Component	GO:0000785	chromatin	APTX	IDA		Human	PMID:20008512
Cellular Component	GO:0000785	chromatin	APTX	IDA		Human	PMID:15044383
Cellular Component	GO:0005730	nucleolus	APTX	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005730	nucleolus	APTX	IDA		Human	PMID:15044383
Cellular Component	GO:0005730	nucleolus	APTX	IDA		Human	PMID:16777843
Cellular Component	GO:0005654	nucleoplasm	APTX	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	APTX	IDA		Human	PMID:15044383
Cellular Component	GO:0005654	nucleoplasm	APTX	IDA		Human	PMID:16777843
Biological Process	GO:0006266	DNA ligation	Aptx	IDA		Mouse	PMID:16964241
Biological Process	GO:0031647	regulation of protein stability	APTX	IMP		Human	PMID:16777843
Biological Process	GO:0000012	single strand break repair	APTX	IMP		Human	PMID:15044383
Biological Process	GO:0000012	single strand break repair	APTX	IDA		Human	PMID:17519253
Biological Process	GO:0000012	single strand break repair	Aptx	IMP		Mouse	MGI:MGI:3665365|PMID:16964241

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern