Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes APBB3
  • Mouse genes Apbb3
  • Rat genes Apbb3
  • Zfish genes apbb3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Apbb3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001540	amyloid-beta binding	Apbb3	IPI	RGD:2139	Rat	PMID:9461550|RGD:634556
Molecular Function	GO:0050750	low-density lipoprotein particle receptor binding	APBB3	IPI	UniProtKB:G3V928	Human	PMID:12153398
Molecular Function	GO:0005515	protein binding	APBB3	IPI	UniProtKB:P05067	Human	PMID:10081969
Molecular Function	GO:0005515	protein binding	APBB3	IPI	UniProtKB:P00533	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	APBB3	IPI	UniProtKB:Q9UN19	Human	PMID:25814554
Molecular Function	GO:0005515	protein binding	APBB3	IPI	UniProtKB:P05067	Human	PMID:31413325
Molecular Function	GO:0005515	protein binding	APBB3	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	APBB3	IPI	UniProtKB:P27986-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	APBB3	IPI	UniProtKB:P05067	Human	PMID:9461550
Molecular Function	GO:0005515	protein binding	Apbb3	IPI	RGD:2128	Rat	PMID:9461550|RGD:634556
Molecular Function	GO:0005515	protein binding	Apbb3	IPI	RGD:69257	Rat	PMID:9461550|RGD:634556
Cellular Component	GO:0015629	actin cytoskeleton	APBB3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	APBB3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	APBB3	IDA		Human	PMID:12153398
Cellular Component	GO:0016020	membrane	APBB3	IDA		Human	PMID:12153398
Cellular Component	GO:0005634	nucleus	APBB3	IDA		Human	PMID:12153398
Cellular Component	GO:0005634	nucleus	Apbb3	IDA		Rat	PMID:12089154|RGD:127285400
Biological Process	GO:1901988	negative regulation of cell cycle phase transition	Apbb3	IDA		Rat	PMID:12089154|RGD:127285400
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Apbb3	IDA		Rat	PMID:12089154|RGD:127285400
Biological Process	GO:0050714	positive regulation of protein secretion	APBB3	IDA		Human	PMID:12153398

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern