Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ANKLE1
  • Mouse genes Ankle1
  • Rat genes Ankle1
  • Zfish genes zgc:85936
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ankle1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004519	endonuclease activity	ANKLE1	IDA		Human	PMID:22399800
Cellular Component	GO:0005737	cytoplasm	ANKLE1	IDA		Human	PMID:22399800
Cellular Component	GO:0005737	cytoplasm	ANKLE1	IDA		Human	PMID:27245214
Cellular Component	GO:0005829	cytosol	ANKLE1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	ANKLE1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	ANKLE1	IDA		Human	PMID:22399800
Cellular Component	GO:0005634	nucleus	ANKLE1	IMP		Human	PMID:27245214
Biological Process	GO:0006974	DNA damage response	ANKLE1	IDA		Human	PMID:22399800
Biological Process	GO:0045950	negative regulation of mitotic recombination	Ankle1	IGI	UniProtKB:O88700	Mouse	MGI:MGI:5800654|PMID:27010503
Biological Process	GO:0006611	protein export from nucleus	ANKLE1	IDA		Human	PMID:22399800
Biological Process	GO:0006611	protein export from nucleus	ANKLE1	IMP		Human	PMID:22399800
Biological Process	GO:1905456	regulation of lymphoid progenitor cell differentiation	Ankle1	IMP		Mouse	MGI:MGI:5800654|PMID:27010503
Biological Process	GO:1905453	regulation of myeloid progenitor cell differentiation	Ankle1	IMP		Mouse	MGI:MGI:5800654|PMID:27010503

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern