Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes AMPD2
  • Mouse genes Ampd2
  • Rat genes Ampd2
  • Zfish genes ampd2a,ampd2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ampd2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003876	AMP deaminase activity	AMPD2	IGI	SGD:S000004498	Human	PMID:23911318
Molecular Function	GO:0003876	AMP deaminase activity	Ampd2	IMP	MGI:MGI:5490144	Mouse	PMID:22212473
Molecular Function	GO:0003876	AMP deaminase activity	Ampd2	IMP	MGI:MGI:5490144	Mouse	PMID:23911318
Molecular Function	GO:0005515	protein binding	AMPD2	IPI	UniProtKB:P54274	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	AMPD2	IPI	UniProtKB:O95273	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	AMPD2	IPI	UniProtKB:O95273	Human	PMID:31515488
Cellular Component	GO:0005829	cytosol	AMPD2	IDA		Human	GO_REF:0000052
Biological Process	GO:0046033	AMP metabolic process	Ampd2	IMP		Mouse	MGI:MGI:5489878|PMID:22212473
Biological Process	GO:0046034	ATP metabolic process	Ampd2	IMP		Mouse	MGI:MGI:5489878|PMID:22212473
Biological Process	GO:0046034	ATP metabolic process	Ampd2	IGI	UniProtKB:O08739	Mouse	MGI:MGI:5506958|PMID:23911318
Biological Process	GO:0042632	cholesterol homeostasis	Ampd2	IMP	MGI:MGI:3848348	Mouse	PMID:25361754
Biological Process	GO:0042632	cholesterol homeostasis	Ampd2	IMP	MGI:MGI:3848343	Mouse	PMID:18974039
Biological Process	GO:0052652	cyclic purine nucleotide metabolic process	AMPD2	IMP		Human	PMID:23911318
Biological Process	GO:0097009	energy homeostasis	AMPD2	IGI	SGD:S000004498	Human	PMID:23911318
Biological Process	GO:0097009	energy homeostasis	Ampd2	IMP	MGI:MGI:5490144	Mouse	PMID:23911318
Biological Process	GO:0046039	GTP metabolic process	Ampd2	IMP		Mouse	MGI:MGI:5489878|PMID:22212473
Biological Process	GO:0046039	GTP metabolic process	Ampd2	IGI	UniProtKB:O08739	Mouse	MGI:MGI:5506958|PMID:23911318
Biological Process	GO:0006188	IMP biosynthetic process	AMPD2	IGI	SGD:S000004498	Human	PMID:23911318
Biological Process	GO:0006188	IMP biosynthetic process	Ampd2	IMP	MGI:MGI:5490144	Mouse	PMID:23911318
Biological Process	GO:0032264	IMP salvage	Ampd2	IMP	MGI:MGI:5490144	Mouse	PMID:22212473
Biological Process	GO:0009117	nucleotide metabolic process	Ampd2	IMP	MGI:MGI:5490144	Mouse	PMID:22212473
Biological Process	GO:0072015	podocyte development	Ampd2	IMP	MGI:MGI:3848348	Mouse	PMID:25361754

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern