Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes AGGF1
  • Mouse genes Aggf1
  • Rat genes Aggf1
  • Zfish genes aggf1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Aggf1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	AGGF1	IPI	UniProtKB:O43508	Human	PMID:14961121
Molecular Function	GO:0005515	protein binding	AGGF1	IPI	UniProtKB:Q8N8X9	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	AGGF1	IPI	UniProtKB:O43143	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGGF1	IPI	UniProtKB:Q8N8X9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGGF1	IPI	UniProtKB:Q96EZ8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGGF1	IPI	UniProtKB:Q9NVF7	Human	PMID:32296183
Cellular Component	GO:0005737	cytoplasm	AGGF1	IDA		Human	PMID:14961121
Cellular Component	GO:0005576	extracellular region	AGGF1	IDA		Human	PMID:14961121
Cellular Component	GO:0048471	perinuclear region of cytoplasm	AGGF1	IDA		Human	PMID:14961121
Biological Process	GO:0001525	angiogenesis	aggf1	IMP	ZFIN:ZDB-MRPHLNO-130320-1	Zfish	PMID:23197652
Biological Process	GO:0001525	angiogenesis	aggf1	IMP	ZFIN:ZDB-MRPHLNO-130320-2	Zfish	PMID:23197652
Biological Process	GO:0007155	cell adhesion	AGGF1	IDA		Human	PMID:14961121
Biological Process	GO:0060217	hemangioblast cell differentiation	aggf1	IMP	ZFIN:ZDB-MRPHLNO-130320-1	Zfish	PMID:24277077
Biological Process	GO:0045766	positive regulation of angiogenesis	AGGF1	IDA		Human	PMID:14961121
Biological Process	GO:0001938	positive regulation of endothelial cell proliferation	AGGF1	IDA		Human	PMID:14961121
Biological Process	GO:0051897	positive regulation of protein kinase B signaling	aggf1	IMP	ZFIN:ZDB-MRPHLNO-130320-1	Zfish	PMID:23197652
Biological Process	GO:0001570	vasculogenesis	aggf1	IMP	ZFIN:ZDB-MRPHLNO-130320-1	Zfish	PMID:23197652
Biological Process	GO:0001570	vasculogenesis	aggf1	IMP	ZFIN:ZDB-MRPHLNO-130320-2	Zfish	PMID:23197652
Biological Process	GO:0060841	venous blood vessel development	aggf1	IMP	ZFIN:ZDB-MRPHLNO-130320-1	Zfish	PMID:25564648
Biological Process	GO:0060841	venous blood vessel development	aggf1	IMP	ZFIN:ZDB-MRPHLNO-130320-1	Zfish	PMID:23197652
Biological Process	GO:0060841	venous blood vessel development	aggf1	IMP	ZFIN:ZDB-MRPHLNO-130320-2	Zfish	PMID:23197652

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern