Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes AFF4
  • Mouse genes Aff4
  • Rat genes Aff4
  • Zfish genes aff4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Aff4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	AFF4	IPI	UniProtKB:O60563	Human	PMID:20153263
Molecular Function	GO:0005515	protein binding	AFF4	IPI	UniProtKB:P42568	Human	PMID:20153263
Molecular Function	GO:0005515	protein binding	AFF4	IPI	UniProtKB:Q03111	Human	PMID:20153263
Molecular Function	GO:0005515	protein binding	AFF4	IPI	UniProtKB:O60563	Human	PMID:21729782
Molecular Function	GO:0005515	protein binding	AFF4	IPI	UniProtKB:P42568	Human	PMID:21729782
Molecular Function	GO:0005515	protein binding	AFF4	IPI	UniProtKB:Q03111	Human	PMID:21729782
Molecular Function	GO:0005515	protein binding	AFF4	IPI	UniProtKB:P04608	Human	PMID:22190034
Molecular Function	GO:0005515	protein binding	AFF4	IPI	UniProtKB:P63010	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	AFF4	IPI	UniProtKB:Q08379	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	AFF4	IPI	UniProtKB:Q12933	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	AFF4	IPI	UniProtKB:Q5JR59	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	AFF4	IPI	UniProtKB:Q8IUQ4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	AFF4	IPI	UniProtKB:O60563	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	Aff4	IPI	UniProtKB:Q80VR2	Mouse	MGI:MGI:5448843|PMID:23273992
Cellular Component	GO:0000791	euchromatin	Aff4	IDA		Mouse	MGI:MGI:5582153|PMID:22195968
Cellular Component	GO:0001650	fibrillar center	AFF4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	AFF4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Aff4	IDA		Mouse	PMID:16024815
Cellular Component	GO:0008023	transcription elongation factor complex	AFF4	IDA		Human	PMID:22195968
Biological Process	GO:0034976	response to endoplasmic reticulum stress	Aff4	IEP		Rat	PMID:31466050|RGD:155631268
Biological Process	GO:0007286	spermatid development	Aff4	IMP	MGI:MGI:3586991	Mouse	PMID:16024815

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern