Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ADGRF5
  • Mouse genes Adgrf5
  • Rat genes Adgrf5
  • Zfish genes adgrf11,adgrf8
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Adgrf5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	ADGRF5	IPI	UniProtKB:P55735-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ADGRF5	IPI	UniProtKB:Q13952-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ADGRF5	IPI	UniProtKB:Q53EP0-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ADGRF5	IPI	UniProtKB:Q9NPB3	Human	PMID:32296183
Cellular Component	GO:0045177	apical part of cell	Adgrf5	IDA		Mouse	PMID:23590306
Cellular Component	GO:0009986	cell surface	ADGRF5	IDA		Human	PMID:23684610
Cellular Component	GO:0031410	cytoplasmic vesicle	ADGRF5	IDA		Human	PMID:23684610
Biological Process	GO:0006112	energy reserve metabolic process	Adgrf5	IMP		Mouse	PMID:22971422
Biological Process	GO:0048821	erythrocyte development	Adgrf5	IGI	MGI:MGI:1925499	Mouse	PMID:28806758
Biological Process	GO:0045444	fat cell differentiation	Adgrf5	IMP		Mouse	PMID:22971422
Biological Process	GO:0003094	glomerular filtration	Adgrf5	IGI	MGI:MGI:1925499	Mouse	PMID:28806758
Biological Process	GO:0042593	glucose homeostasis	Adgrf5	IMP		Mouse	PMID:22971422
Biological Process	GO:0042116	macrophage activation	Adgrf5	IMP	MGI:MGI:5547987	Mouse	PMID:25778400
Biological Process	GO:0043031	negative regulation of macrophage activation	Adgrf5	IMP	MGI:MGI:5547987	Mouse	PMID:25778400
Biological Process	GO:0061626	pharyngeal arch artery morphogenesis	Adgrf5	IGI	MGI:MGI:1925499	Mouse	PMID:28806758
Biological Process	GO:0008654	phospholipid biosynthetic process	Adgrf5	IMP		Mouse	PMID:23590306
Biological Process	GO:0071073	positive regulation of phospholipid biosynthetic process	Adgrf5	IMP		Mouse	PMID:23590306
Biological Process	GO:0019216	regulation of lipid metabolic process	Adgrf5	IMP		Mouse	PMID:22971422
Biological Process	GO:0043129	surfactant homeostasis	Adgrf5	IMP		Mouse	PMID:28806758
Biological Process	GO:0043129	surfactant homeostasis	Adgrf5	IMP		Mouse	PMID:23590306
Biological Process	GO:0043129	surfactant homeostasis	Adgrf5	IMP	MGI:MGI:5490511	Mouse	PMID:23684610

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern