Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ADAP2
  • Mouse genes Adap2
  • Rat genes Adap2
  • Zfish genes adap2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Adap2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005545	1-phosphatidylinositol binding	Adap2	IDA		Rat	PMID:12018390|RGD:1299471
Molecular Function	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding	ADAP2	IDA		Human	PMID:14690521
Molecular Function	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	ADAP2	IDA		Human	PMID:14690521
Molecular Function	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	Adap2	IDA		Rat	PMID:12018390|RGD:1299471
Molecular Function	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	Adap2	IDA		Rat	PMID:12018390|RGD:1299471
Molecular Function	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	Adap2	IDA		Rat	PMID:12018390|RGD:1299471
Molecular Function	GO:0005515	protein binding	ADAP2	IPI	UniProtKB:Q9Y6K9	Human	PMID:20098747
Cellular Component	GO:0005737	cytoplasm	ADAP2	IDA		Human	PMID:14690521
Cellular Component	GO:0016020	membrane	Adap2	IDA		Rat	PMID:12018390|RGD:1299471
Cellular Component	GO:0005740	mitochondrial envelope	Adap2	IDA		Rat	PMID:12018390|RGD:1299471
Cellular Component	GO:0005886	plasma membrane	ADAP2	IDA		Human	PMID:14690521
Biological Process	GO:0003171	atrioventricular valve development	adap2	IMP	ZFIN:ZDB-MRPHLNO-140710-3	Zfish	PMID:24711647
Biological Process	GO:0007507	heart development	ADAP2	IEP		Human	PMID:16138909
Biological Process	GO:0007507	heart development	adap2	IMP	ZFIN:ZDB-MRPHLNO-140710-3	Zfish	PMID:24711647
Biological Process	GO:0007507	heart development	adap2	IMP	ZFIN:ZDB-MRPHLNO-140710-4	Zfish	PMID:24711647
Biological Process	GO:0003146	heart jogging	adap2	IMP	ZFIN:ZDB-MRPHLNO-140710-3	Zfish	PMID:24711647
Biological Process	GO:0001947	heart looping	adap2	IMP	ZFIN:ZDB-MRPHLNO-140710-3	Zfish	PMID:24711647
Biological Process	GO:0048017	inositol lipid-mediated signaling	ADAP2	IDA		Human	PMID:14690521

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern