Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ACOX2
  • Mouse genes Acox2
  • Rat genes Acox2
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Acox2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0033791	3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity	ACOX2	IDA		Human	PMID:27884763
Molecular Function	GO:0033791	3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity	Acox2	IDA		Rat	PMID:1400324|RGD:2299949
Molecular Function	GO:0033791	3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity	Acox2	IDA		Rat	PMID:8654595|RGD:2299971
Molecular Function	GO:0005504	fatty acid binding	Acox2	IDA		Rat	PMID:1400324|RGD:2299949
Molecular Function	GO:0005504	fatty acid binding	Acox2	IDA		Rat	PMID:8654595|RGD:2299971
Molecular Function	GO:0050660	flavin adenine dinucleotide binding	Acox2	IDA		Rat	PMID:8654595|RGD:2299971
Molecular Function	GO:0005515	protein binding	ACOX2	IPI	UniProtKB:P63172	Human	PMID:32296183
Cellular Component	GO:0005829	cytosol	ACOX2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ACOX2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005777	peroxisome	ACOX2	IDA		Human	PMID:2079609
Cellular Component	GO:0005777	peroxisome	ACOX2	IMP		Human	PMID:27884763
Cellular Component	GO:0005777	peroxisome	ACOX2	IDA		Human	PMID:8943006
Cellular Component	GO:0005777	peroxisome	Acox2	IDA		Rat	PMID:1400324|RGD:2299949
Cellular Component	GO:0005777	peroxisome	Acox2	IDA		Rat	PMID:14561759|RGD:1580664
Cellular Component	GO:0005777	peroxisome	Acox2	IDA		Rat	PMID:8654595|RGD:2299971
Cellular Component	GO:0005777	peroxisome	Acox2	IDA		Rat	PMID:8947475|RGD:724759
Biological Process	GO:0006635	fatty acid beta-oxidation	Acox2	IDA		Rat	PMID:1400324|RGD:2299949
Biological Process	GO:0006635	fatty acid beta-oxidation	Acox2	IDA		Rat	PMID:8654595|RGD:2299971
Biological Process	GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase	ACOX2	IDA		Human	PMID:27884763
Biological Process	GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase	ACOX2	IMP		Human	PMID:27884763
Biological Process	GO:0006631	fatty acid metabolic process	Acox2	IEP		Rat	PMID:8947475|RGD:724759
Biological Process	GO:0010942	positive regulation of cell death	ACOX2	IDA		Human	PMID:27884763
Biological Process	GO:1902884	positive regulation of response to oxidative stress	ACOX2	IDA		Human	PMID:27884763

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern