Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ACER2
  • Mouse genes Acer2
  • Rat genes Acer2
  • Zfish genes acer2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Acer2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0071633	dihydroceramidase activity	ACER2	IMP		Human	PMID:20207939
Molecular Function	GO:0071633	dihydroceramidase activity	ACER2	IDA		Human	PMID:20628055
Molecular Function	GO:0071633	dihydroceramidase activity	Acer2	IMP		Mouse	MGI:MGI:6116621|PMID:29401619
Molecular Function	GO:0017040	N-acylsphingosine amidohydrolase activity	ACER2	IDA		Human	PMID:16940153
Molecular Function	GO:0017040	N-acylsphingosine amidohydrolase activity	ACER2	IDA		Human	PMID:20089856
Cellular Component	GO:0005794	Golgi apparatus	ACER2	IDA		Human	PMID:16940153
Cellular Component	GO:0000139	Golgi membrane	ACER2	IDA		Human	PMID:20089856
Biological Process	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	ACER2	IMP		Human	PMID:20628055
Biological Process	GO:0071466	cellular response to xenobiotic stimulus	ACER2	IEP		Human	PMID:20628055
Biological Process	GO:0046514	ceramide catabolic process	ACER2	IMP		Human	PMID:16940153
Biological Process	GO:0046514	ceramide catabolic process	ACER2	IMP		Human	PMID:20207939
Biological Process	GO:0006974	DNA damage response	ACER2	IDA		Human	PMID:26943039
Biological Process	GO:0030330	DNA damage response, signal transduction by p53 class mediator	ACER2	IMP		Human	PMID:28294157
Biological Process	GO:0030330	DNA damage response, signal transduction by p53 class mediator	ACER2	IMP		Human	PMID:29229990
Biological Process	GO:0033629	negative regulation of cell adhesion mediated by integrin	ACER2	IDA		Human	PMID:18945876
Biological Process	GO:0001953	negative regulation of cell-matrix adhesion	ACER2	IDA		Human	PMID:18945876
Biological Process	GO:0010942	positive regulation of cell death	ACER2	IMP		Human	PMID:20628055
Biological Process	GO:0008284	positive regulation of cell population proliferation	ACER2	IDA		Human	PMID:16940153
Biological Process	GO:0042981	regulation of apoptotic process	ACER2	IMP		Human	PMID:26943039
Biological Process	GO:0042981	regulation of apoptotic process	ACER2	IMP		Human	PMID:28294157
Biological Process	GO:0042981	regulation of apoptotic process	ACER2	IMP		Human	PMID:29229990
Biological Process	GO:0010506	regulation of autophagy	ACER2	IMP		Human	PMID:28294157
Biological Process	GO:0060049	regulation of protein glycosylation	ACER2	IMP		Human	PMID:20089856
Biological Process	GO:0032526	response to retinoic acid	ACER2	IDA		Human	PMID:18945876
Biological Process	GO:0046512	sphingosine biosynthetic process	ACER2	IDA		Human	PMID:16940153
Biological Process	GO:0046512	sphingosine biosynthetic process	ACER2	IDA		Human	PMID:20089856
Biological Process	GO:0046512	sphingosine biosynthetic process	ACER2	IMP		Human	PMID:20207939
Biological Process	GO:0046512	sphingosine biosynthetic process	ACER2	IDA		Human	PMID:20628055
Biological Process	GO:0046512	sphingosine biosynthetic process	Acer2	IMP		Mouse	MGI:MGI:6116621|PMID:29401619

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern