Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Map1lc3b  microtubule-associated protein 1 light chain 3 beta   (Synonyms: 1010001C15Rik, Atg8, LC3b, Map1lc3)
Results	Reference
1	J:171267 Banks GT, Haas MA, Line S, Shepherd HL, Alqatari M, Stewart S, Rishal I, Philpott A, Kalmar B, Kuta A, Groves M, Parkinson N, Acevedo-Arozena A, Brandner S, Bannerman D, Greensmith L, Hafezparast M, Koltzenburg M, Deacon R, Fainzilber M, Fisher EM, Behavioral and Other Phenotypes in a Cytoplasmic Dynein Light Intermediate Chain 1 Mutant Mouse. J Neurosci. 2011 Apr 6;31(14):5483-5494
1	J:272052 Cheng X, Ma X, Zhu Q, Song D, Ding X, Li L, Jiang X, Wang X, Tian R, Su H, Shen Z, Chen S, Liu T, Gong W, Liu W, Sun Q, Pacer Is a Mediator of mTORC1 and GSK3-TIP60 Signaling in Regulation of Autophagosome Maturation and Lipid Metabolism. Mol Cell. 2019 Feb 21;73(4):788-802.e7
1	J:302676 Cheong H, Wu J, Gonzales LK, Guttentag SH, Thompson CB, Lindsten T, Analysis of a lung defect in autophagy-deficient mouse strains. Autophagy. 2014 Jan;10(1):45-56
1	J:262653 D'Ignazio L, Michel M, Beyer M, Thompson K, Forabosco A, Schlessinger D, Pelosi E, Lhx8 ablation leads to massive autophagy of mouse oocytes associated with DNA damage. Biol Reprod. 2018 Apr 1;98(4):532-542
1*	J:225886 de Iriarte Rodriguez R, Pulido S, Rodriguez-de la Rosa L, Magarinos M, Varela-Nieto I, Age-regulated function of autophagy in the mouse inner ear. Hear Res. 2015 Dec;330(Pt A):39-50
1	J:307971 De Risi M, Tufano M, Alvino FG, Ferraro MG, Torromino G, Gigante Y, Monfregola J, Marrocco E, Pulcrano S, Tunisi L, Lubrano C, Papy-Garcia D, Tuchman Y, Salleo A, Santoro F, Bellenchi GC, Cristino L, Ballabio A, Fraldi A, De Leonibus E, Altered heparan sulfate metabolism during development triggers dopamine-dependent autistic-behaviours in models of lysosomal storage disorders. Nat Commun. 2021 Jun 9;12(1):3495
1	J:290823 Feng J, Zhang Y, Ren X, Li D, Fu H, Liu C, Zhou W, Liu Q, Liu Q, Wu M, Leucine-rich repeat containing 4 act as an autophagy inhibitor that restores sensitivity of glioblastoma to temozolomide. Oncogene. 2020 Jun;39(23):4551-4566
1	J:306853 Feng Q, Luo Y, Zhang XN, Yang XF, Hong XY, Sun DS, Li XC, Hu Y, Li XG, Zhang JF, Li X, Yang Y, Wang Q, Liu GP, Wang JZ, MAPT/Tau accumulation represses autophagy flux by disrupting IST1-regulated ESCRT-III complex formation: a vicious cycle in Alzheimer neurodegeneration. Autophagy. 2020 Apr;16(4):641-658
1	J:330579 Gambarotto L, Metti S, Chrisam M, Cerqua C, Sabatelli P, Armani A, Zanon C, Spizzotin M, Castagnaro S, Strappazzon F, Grumati P, Cescon M, Braghetta P, Trevisson E, Cecconi F, Bonaldo P, Ambra1 deficiency impairs mitophagy in skeletal muscle. J Cachexia Sarcopenia Muscle. 2022 Aug;13(4):2211-2224
1	J:346909 Ha HT, Liu S, Nguyen XT, Vo LK, Leong NC, Nguyen DT, Balamurugan S, Lim PY, Wu Y, Seong E, Nguyen TQ, Oh J, Wenk MR, Cazenave-Gassiot A, Yapici Z, Ong WY, Burmeister M, Nguyen LN, Lack of SPNS1 results in accumulation of lysolipids and lysosomal storage disease in mouse models. JCI Insight. 2024 Mar 7;:e175462
1	J:316639 He MY, Wang G, Han SS, Jin Y, Li H, Wu X, Ma ZL, Cheng X, Tang X, Yang X, Liu GS, Nrf2 signalling and autophagy are involved in diabetes mellitus-induced defects in the development of mouse placenta. Open Biol. 2016 Jul;6(7)
1	J:235665 He S, Limi S, McGreal RS, Xie Q, Brennan LA, Kantorow WL, Kokavec J, Majumdar R, Hou H Jr, Edelmann W, Liu W, Ashery-Padan R, Zavadil J, Kantorow M, Skoultchi AI, Stopka T, Cvekl A, Chromatin remodeling enzyme Snf2h regulates embryonic lens differentiation and denucleation. Development. 2016 Jun 1;143(11):1937-47
1	J:224310 Ishihara T, Ban-Ishihara R, Maeda M, Matsunaga Y, Ichimura A, Kyogoku S, Aoki H, Katada S, Nakada K, Nomura M, Mizushima N, Mihara K, Ishihara N, Dynamics of mitochondrial DNA nucleoids regulated by mitochondrial fission is essential for maintenance of homogeneously active mitochondria during neonatal heart development. Mol Cell Biol. 2015 Jan;35(1):211-23
1*	J:284681 Ivankovic D, Drew J, Lesept F, White IJ, Lopez Domenech G, Tooze SA, Kittler JT, Axonal autophagosome maturation defect through failure of ATG9A sorting underpins pathology in AP-4 deficiency syndrome. Autophagy. 2020 Mar;16(3):391-407
1	J:335218 Knaus LS, Basilico B, Malzl D, Gerykova Bujalkova M, Smogavec M, Schwarz LA, Gorkiewicz S, Amberg N, Pauler FM, Knittl-Frank C, Tassinari M, Maulide N, Rulicke T, Menche J, Hippenmeyer S, Novarino G, Large neutral amino acid levels tune perinatal neuronal excitability and survival. Cell. 2023 Apr 27;186(9):1950-1967.e25
1	J:222854 Laguna A, Schintu N, Nobre A, Alvarsson A, Volakakis N, Jacobsen JK, Gomez-Galan M, Sopova E, Joodmardi E, Yoshitake T, Deng Q, Kehr J, Ericson J, Svenningsson P, Shupliakov O, Perlmann T, Dopaminergic control of autophagic-lysosomal function implicates Lmx1b in Parkinson's disease. Nat Neurosci. 2015 Jun;18(6):826-35
1	J:329967 Li H, Li C, Zhai W, Zhang X, Li L, Wu B, Yu B, Zhang P, Li J, Cui CP, Zhang L, Destabilization of TP53 by USP10 is essential for neonatal autophagy and survival. Cell Rep. 2022 Oct 4;41(1):111435
1	J:301660 Li M, Lu G, Hu J, Shen X, Ju J, Gao Y, Qu L, Xia Y, Chen Y, Bai Y, EVA1A/TMEM166 Regulates Embryonic Neurogenesis by Autophagy. Stem Cell Reports. 2016 Mar 8;6(3):396-410
1	J:163712 Marino G, Fernandez AF, Cabrera S, Lundberg YW, Cabanillas R, Rodriguez F, Salvador-Montoliu N, Vega JA, Germana A, Fueyo A, Freije JM, Lopez-Otin C, Autophagy is essential for mouse sense of balance. J Clin Invest. 2010 Jul 1;120(7):2331-44
1	J:233172 Mehanna S, Suzuki C, Shibata M, Sunabori T, Imanaka T, Araki K, Yamamura K, Uchiyama Y, Ohmuraya M, Cathepsin D in pancreatic acinar cells is implicated in cathepsin B and L degradation, but not in autophagic activity. Biochem Biophys Res Commun. 2016 Jan 15;469(3):405-11
1	J:243986 Ohgaki R, Ohmori T, Hara S, Nakagomi S, Kanai-Azuma M, Kaneda-Nakashima K, Okuda S, Nagamori S, Kanai Y, Essential Roles of L-Type Amino Acid Transporter 1 in Syncytiotrophoblast Development by Presenting Fusogenic 4F2hc. Mol Cell Biol. 2017 Jun 01;37(11)
1	J:303303 Pan M, Yin Y, Wang X, Wang Q, Zhang L, Hu H, Wang C, Mice deficient in UXT exhibit retinitis pigmentosa-like features via aberrant autophagy activation. Autophagy. 2020 Aug 2;:1-16
1	J:212629 Papanicolaou KN, Kikuchi R, Ngoh GA, Coughlan KA, Dominguez I, Stanley WC, Walsh K, Mitofusins 1 and 2 are essential for postnatal metabolic remodeling in heart. Circ Res. 2012 Sep 28;111(8):1012-26
1	J:186307 Peng C, Ye J, Yan S, Kong S, Shen Y, Li C, Li Q, Zheng Y, Deng K, Xu T, Tao W, Ablation of vacuole protein sorting 18 (Vps18) gene leads to neurodegeneration and impaired neuronal migration by disrupting multiple vesicle transport pathways to lysosomes. J Biol Chem. 2012 Sep 21;287(39):32861-73
1*	J:170578 Perera S, Holt MR, Mankoo BS, Gautel M, Developmental regulation of MURF ubiquitin ligases and autophagy proteins nbr1, p62/SQSTM1 and LC3 during cardiac myofibril assembly and turnover. Dev Biol. 2011 Mar 1;351(1):46-61
1	J:342544 Radzishevsky I, Odeh M, Bodner O, Zubedat S, Shaulov L, Litvak M, Esaki K, Yoshikawa T, Agranovich B, Li WH, Radzishevsky A, Gottlieb E, Avital A, Wolosker H, Impairment of serine transport across the blood-brain barrier by deletion of Slc38a5 causes developmental delay and motor dysfunction. Proc Natl Acad Sci U S A. 2023 Oct 17;120(42):e2302780120
1	J:197614 Wang C, Liang CC, Bian ZC, Zhu Y, Guan JL, FIP200 is required for maintenance and differentiation of postnatal neural stem cells. Nat Neurosci. 2013 May;16(5):532-42
1*	J:217554 Wang S, Li B, Qiao H, Lv X, Liang Q, Shi Z, Xia W, Ji F, Jiao J, Autophagy-related gene Atg5 is essential for astrocyte differentiation in the developing mouse cortex. EMBO Rep. 2014 Oct;15(10):1053-61
1*	J:221937 Watson JA, Bhattacharyya BJ, Vaden JH, Wilson JA, Icyuz M, Howard AD, Phillips E, DeSilva TM, Siegal GP, Bean AJ, King GD, Phillips SE, Miller RJ, Wilson SM, Motor and Sensory Deficits in the teetering Mice Result from Mutation of the ESCRT Component HGS. PLoS Genet. 2015 Jun;11(6):e1005290
1*	J:299531 Wei L, Zheng YY, Sun J, Wang P, Tao T, Li Y, Chen X, Sang Y, Chong D, Zhao W, Zhou Y, Wang Y, Jiang Z, Qiu T, Li CJ, Zhu MS, Zhang X, GGPP depletion initiates metaflammation through disequilibrating CYB5R3-dependent eicosanoid metabolism. J Biol Chem. 2020 Nov 20;295(47):15988-16001
1	J:280538 Yeganeh B, Lee J, Ermini L, Lok I, Ackerley C, Post M, Autophagy is required for lung development and morphogenesis. J Clin Invest. 2019 Jun 4;129(7):2904-2919