Assay
Age
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Western blot
Postnatal
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Ttn titin (Synonyms: 1100001C23Rik, 2310036G12Rik, 2310057K23Rik, 2310074I15Rik, connectin, D330041I19Rik, D830007G01Rik, L56, mdm, shru) | |
Results | Reference |
1 | J:143692 Bang ML, Centner T, Fornoff F, Geach AJ, Gotthardt M, McNabb M, Witt CC, Labeit D, Gregorio CC, Granzier H, Labeit S, The complete gene sequence of titin, expression of an unusual approximately 700-kDa titin isoform, and its interaction with obscurin identify a novel Z-line to I-band linking system. Circ Res. 2001 Nov 23;89(11):1065-72 |
1 | J:291994 de Groot NE, van den Hoogenhof MMG, Najafi A, van der Made I, van der Velden J, Beqqali A, Pinto YM, Creemers EE, Heterozygous loss of Rbm24 in the adult mouse heart increases sarcomere slack length but does not affect function. Sci Rep. 2020 May 6;10(1):7687 |
1* | J:152736 Gramlich M, Michely B, Krohne C, Heuser A, Erdmann B, Klaassen S, Hudson B, Magarin M, Kirchner F, Todiras M, Granzier H, Labeit S, Thierfelder L, Gerull B, Stress-induced dilated cardiomyopathy in a knock-in mouse model mimicking human titin-based disease. J Mol Cell Cardiol. 2009 Sep;47(3):352-8 |
1* | J:296804 Swist S, Unger A, Li Y, Voge A, von Frieling-Salewsky M, Skarlen A, Cacciani N, Braun T, Larsson L, Linke WA, Maintenance of sarcomeric integrity in adult muscle cells crucially depends on Z-disc anchored titin. Nat Commun. 2020 Sep 8;11(1):4479 |
1 | J:111284 Weinert S, Bergmann N, Luo X, Erdmann B, Gotthardt M, M line-deficient titin causes cardiac lethality through impaired maturation of the sarcomere. J Cell Biol. 2006 May 22;173(4):559-70 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/21/2024 MGI 6.23 |
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