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Gene Expression Literature Summary
Assay
Age
Western blot
Postnatal

13 matching records from 13 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Plp1  proteolipid protein (myelin) 1   (Synonyms: DM20, Plp)
Results  Reference
1*J:57684 Bongarzone ER, Campagnoni CW, Kampf K, Jacobs EC, Handley VW, Schonmann V, Campagnoni AT, Identification of a new exon in the myelin proteolipid protein gene encoding novel protein isoforms that are restricted to the somata of oligodendrocytes and neurons. J Neurosci. 1999 Oct 1;19(19):8349-57
1J:333367 Cifuentes-Diaz C, Canali G, Garcia M, Druart M, Manett T, Savariradjane M, Guillaume C, Le Magueresse C, Goutebroze L, Differential impacts of Cntnap2 heterozygosity and Cntnap2 null homozygosity on axon and myelinated fiber development in mouse. Front Neurosci. 2023;17:1100121
1J:242754 Frohlich D, Suchowerska AK, Spencer ZH, von Jonquieres G, Klugmann CB, Bongers A, Delerue F, Stefen H, Ittner LM, Fath T, Housley GD, Klugmann M, In vivocharacterization of the aspartyl-tRNA synthetase DARS: Homing in on the leukodystrophy HBSL. Neurobiol Dis. 2017 Jan;97(Pt A):24-35
1J:317408 Grad M, Nir A, Levy G, Trangle SS, Shapira G, Shomron N, Assaf Y, Barak B, Altered White Matter and microRNA Expression in a Murine Model Related to Williams Syndrome Suggests That miR-34b/c Affects Brain Development via Ptpru and Dcx Modulation. Cells. 2022 Jan 4;11(1)
1J:159670 Kumar S, Biancotti JC, Matalon R, de Vellis J, Lack of aspartoacylase activity disrupts survival and differentiation of neural progenitors and oligodendrocytes in a mouse model of Canavan disease. J Neurosci Res. 2009 Nov 15;87(15):3415-27
1J:294401 Lee H, Thacker S, Sarn N, Dutta R, Eng C, Constitutional mislocalization of Pten drives precocious maturation in oligodendrocytes and aberrant myelination in model of autism spectrum disorder. Transl Psychiatry. 2019 Jan 17;9(1):13
1J:331420 Pijuan I, Balducci E, Soto-Sanchez C, Fernandez E, Barallobre MJ, Arbones ML, Impaired macroglial development and axonal conductivity contributes to the neuropathology of DYRK1A-related intellectual disability syndrome. Sci Rep. 2022 Nov 19;12(1):19912
1J:123227 See J, Mamontov P, Ahn K, Wine-Lee L, Crenshaw EB 3rd, Grinspan JB, BMP signaling mutant mice exhibit glial cell maturation defects. Mol Cell Neurosci. 2007 May;35(1):171-82
1J:94807 Southwood C, He C, Garbern J, Kamholz J, Arroyo E, Gow A, CNS myelin paranodes require Nkx6-2 homeoprotein transcriptional activity for normal structure. J Neurosci. 2004 Dec 15;24(50):11215-25
1*J:105188 Sporkel O, Uschkureit T, Bussow H, Stoffel W, Oligodendrocytes expressing exclusively the DM20 isoform of the proteolipid protein gene: myelination and development. Glia. 2002 Jan;37(1):19-30
1J:62287 Stecca B, Southwood CM, Gragerov A, Kelley KA, Friedrich VL Jr, Gow A, The evolution of lipophilin genes from invertebrates to tetrapods: DM-20 cannot replace proteolipid protein in CNS myelin. J Neurosci. 2000 Jun 1;20(11):4002-10
1J:167894 Vondran MW, Clinton-Luke P, Honeywell JZ, Dreyfus CF, BDNF+/- mice exhibit deficits in oligodendrocyte lineage cells of the basal forebrain. Glia. 2010 May;58(7):848-56
1J:168571 Zou J, Zhou L, Du XX, Ji Y, Xu J, Tian J, Jiang W, Zou Y, Yu S, Gan L, Luo M, Yang Q, Cui Y, Yang W, Xia X, Chen M, Zhao X, Shen Y, Chen PY, Worley PF, Xiao B, Rheb1 is required for mTORC1 and myelination in postnatal brain development. Dev Cell. 2011 Jan 18;20(1):97-108

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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory