Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Mbp  myelin basic protein   (Synonyms: golli-mbp, Hmbpr, jve)
Results	Reference
1*	J:253968 Abdelhamed Z, Vuong SM, Hill L, Shula C, Timms A, Beier D, Campbell K, Mangano FT, Stottmann RW, Goto J, A mutation in Ccdc39 causes neonatal hydrocephalus with abnormal motile cilia development in mice. Development. 2018 Jan 9;145(1):dev154500
1	J:164021 Bremer J, O'Connor T, Tiberi C, Rehrauer H, Weis J, Aguzzi A, Ablation of Dicer from murine Schwann cells increases their proliferation while blocking myelination. PLoS One. 2010;5(8):e12450
1	J:187211 Bribian A, Fontana X, Llorens F, Gavin R, Reina M, Garcia-Verdugo JM, Torres JM, de Castro F, del Rio JA, Role of the cellular prion protein in oligodendrocyte precursor cell proliferation and differentiation in the developing and adult mouse CNS. PLoS One. 2012;7(4):e33872
1*	J:140877 Charnay Y, Imhof A, Vallet PG, Hakkoum D, Lathuiliere A, Poku N, Aronow B, Kovari E, Bouras C, Giannakopoulos P, Clusterin expression during fetal and postnatal CNS development in mouse. Neuroscience. 2008 Aug 26;155(3):714-24
1	J:154602 Chen Y, Wu H, Wang S, Koito H, Li J, Ye F, Hoang J, Escobar SS, Gow A, Arnett HA, Trapp BD, Karandikar NJ, Hsieh J, Lu QR, The oligodendrocyte-specific G protein-coupled receptor GPR17 is a cell-intrinsic timer of myelination. Nat Neurosci. 2009 Nov;12(11):1398-406
1	J:96523 Cho KS, Yang L, Lu B, Feng Ma H, Huang X, Pekny M, Chen DF, Re-establishing the regenerative potential of central nervous system axons in postnatal mice. J Cell Sci. 2005 Mar 1;118(Pt 5):863-72
1	J:305180 Choi I, Choi DJ, Yang H, Woo JH, Chang MY, Kim JY, Sun W, Park SM, Jou I, Lee SH, Joe EH, PINK1 expression increases during brain development and stem cell differentiation, and affects the development of GFAP-positive astrocytes. Mol Brain. 2016 Jan 8;9:5
1	J:333367 Cifuentes-Diaz C, Canali G, Garcia M, Druart M, Manett T, Savariradjane M, Guillaume C, Le Magueresse C, Goutebroze L, Differential impacts of Cntnap2 heterozygosity and Cntnap2 null homozygosity on axon and myelinated fiber development in mouse. Front Neurosci. 2023;17:1100121
1	J:291492 Dobrowolski M, Cave C, Levy-Myers R, Lee C, Park S, Choi BR, Xiao B, Yang W, Sockanathan S, GDE3 regulates oligodendrocyte precursor proliferation via release of soluble CNTFRalpha. Development. 2020 Jan 23;147(2):dev180695
1	J:250520 Dubey M, Bugiani M, Ridder MC, Postma NL, Brouwers E, Polder E, Jacobs JG, Baayen JC, Klooster J, Kamermans M, Aardse R, de Kock CP, Dekker MP, van Weering JR, Heine VM, Abbink TE, Scheper GC, Boor I, Lodder JC, Mansvelder HD, van der Knaap MS, Mice with megalencephalic leukoencephalopathy with cysts: a developmental angle. Ann Neurol. 2015 Jan;77(1):114-31
1	J:248325 Figlia G, Norrmen C, Pereira JA, Gerber D, Suter U, Dual function of the PI3K-Akt-mTORC1 axis in myelination of the peripheral nervous system. Elife. 2017 Sep 07;6:e29241
1	J:242754 Frohlich D, Suchowerska AK, Spencer ZH, von Jonquieres G, Klugmann CB, Bongers A, Delerue F, Stefen H, Ittner LM, Fath T, Housley GD, Klugmann M, In vivocharacterization of the aspartyl-tRNA synthetase DARS: Homing in on the leukodystrophy HBSL. Neurobiol Dis. 2017 Jan;97(Pt A):24-35
1	J:195809 Fujikura K, Setsu T, Tanigaki K, Abe T, Kiyonari H, Terashima T, Sakisaka T, Kif14 mutation causes severe brain malformation and hypomyelination. PLoS One. 2013;8(1):e53490
1*	J:106808 Gabanella F, Carissimi C, Usiello A, Pellizzoni L, The activity of the spinal muscular atrophy protein is regulated during development and cellular differentiation. Hum Mol Genet. 2005 Dec 1;14(23):3629-42
1*	J:174479 Gil V, Bichler Z, Lee JK, Seira O, Llorens F, Bribian A, Morales R, Claverol-Tinture E, Soriano E, Sumoy L, Zheng B, Del Rio JA, Developmental expression of the oligodendrocyte myelin glycoprotein in the mouse telencephalon. Cereb Cortex. 2010 Aug;20(8):1769-79
1	J:317408 Grad M, Nir A, Levy G, Trangle SS, Shapira G, Shomron N, Assaf Y, Barak B, Altered White Matter and microRNA Expression in a Murine Model Related to Williams Syndrome Suggests That miR-34b/c Affects Brain Development via Ptpru and Dcx Modulation. Cells. 2022 Jan 4;11(1)
1*	J:324216 Gross I, Brandt N, Vonk D, Koper F, Wohlbrand L, Rabus R, Witt M, Heep A, Plosch T, Hipp MS, Brauer AU, Plasticity-Related Gene 5 Is Expressed in a Late Phase of Neurodifferentiation After Neuronal Cell-Fate Determination. Front Cell Neurosci. 2022;16:797588
1	J:153219 Grossmann KS, Wende H, Paul FE, Cheret C, Garratt AN, Zurborg S, Feinberg K, Besser D, Schulz H, Peles E, Selbach M, Birchmeier W, Birchmeier C, The tyrosine phosphatase Shp2 (PTPN11) directs Neuregulin-1/ErbB signaling throughout Schwann cell development. Proc Natl Acad Sci U S A. 2009 Sep 29;106(39):16704-9
1	J:189718 Gu Z, Liu Y, Zhang Y, Jin S, Chen Q, Goltzman D, Karaplis A, Miao D, Absence of PTHrP nuclear localization and carboxyl terminus sequences leads to abnormal brain development and function. PLoS One. 2012;7(7):e41542
1	J:96967 Hahn KL, Johnson J, Beres BJ, Howard S, Wilson-Rawls J, Lunatic fringe null female mice are infertile due to defects in meiotic maturation. Development. 2005 Feb;132(4):817-28
1	J:230934 Hashimoto M, Murata K, Ishida J, Kanou A, Kasuya Y, Fukamizu A, Severe Hypomyelination and Developmental Defects Are Caused in Mice Lacking Protein Arginine Methyltransferase 1 (PRMT1) in the Central Nervous System. J Biol Chem. 2016 Jan 29;291(5):2237-45
1	J:337770 Hu M, Bodnar B, Zhang Y, Xie F, Li F, Li S, Zhao J, Zhao R, Gedupoori N, Mo Y, Lin L, Li X, Meng W, Yang X, Wang H, Barbe MF, Srinivasan S, Bethea JR, Mo X, Xu H, Hu W, Defective neurite elongation and branching in Nibp/Trappc9 deficient zebrafish and mice. Int J Biol Sci. 2023;19(10):3226-3248
1*	J:34465 Jaegle M, Mandemakers W, Broos L, Zwart R, Karis A, Visser P , Grosveld F , Meijer D, The POU factor Oct-6 and Schwann cell differentiation. Science. 1996 26;273(5274):507-10
1	J:306095 Ji F, Wang W, Feng C, Gao F, Jiao J, Brain-specific Wt1 deletion leads to depressive-like behaviors in mice via the recruitment of Tet2 to modulate Epo expression. Mol Psychiatry. 2020 May 11;
1	J:240829 Jiang M, Liu L, He X, Wang H, Lin W, Wang H, Yoon SO, Wood TL, Lu QR, Regulation of PERK-eIF2alpha signalling by tuberous sclerosis complex-1 controls homoeostasis and survival of myelinating oligodendrocytes. Nat Commun. 2016 Jul 15;7:12185
1	J:309368 Jiang W, Yang W, Yang W, Zhang J, Pang D, Gan L, Luo L, Fan Y, Liu Y, Chen M, Identification of Tmem10 as a novel late-stage oligodendrocytes marker for detecting hypomyelination. Int J Biol Sci. 2013;10(1):33-42
1	J:144171 Kao SC, Wu H, Xie J, Chang CP, Ranish JA, Graef IA, Crabtree GR, Calcineurin/NFAT signaling is required for neuregulin-regulated Schwann cell differentiation. Science. 2009 Jan 30;323(5914):651-4
1	J:159670 Kumar S, Biancotti JC, Matalon R, de Vellis J, Lack of aspartoacylase activity disrupts survival and differentiation of neural progenitors and oligodendrocytes in a mouse model of Canavan disease. J Neurosci Res. 2009 Nov 15;87(15):3415-27
1*	J:49781 Landry CF, Pribyl TM, Ellison JA, Givogri MI, Kampf K, Campagnoni CW, Campagnoni AT, Embryonic expression of the myelin basic protein gene: identification of a promoter region that targets transgene expression to pioneer neurons. J Neurosci. 1998 Sep 15;18(18):7315-27
1	J:294401 Lee H, Thacker S, Sarn N, Dutta R, Eng C, Constitutional mislocalization of Pten drives precocious maturation in oligodendrocytes and aberrant myelination in model of autism spectrum disorder. Transl Psychiatry. 2019 Jan 17;9(1):13
1	J:188328 Li X, Newbern JM, Wu Y, Morgan-Smith M, Zhong J, Charron J, Snider WD, MEK Is a Key Regulator of Gliogenesis in the Developing Brain. Neuron. 2012 Sep 20;75(6):1035-50
1	J:280216 Liu W, Tang FL, Erion J, Xiao H, Ye J, Xiong WC, Vps35 haploinsufficiency results in degenerative-like deficit in mouse retinal ganglion neurons and impairment of optic nerve injury-induced gliosis. Mol Brain. 2014 Feb 11;7:10
1*	J:15845 Mathisen PM, Pease S, Garvey J, Hood L, Readhead C, Identification of an embryonic isoform of myelin basic protein that is expressed widely in the mouse embryo. Proc Natl Acad Sci U S A. 1993 Nov 1;90(21):10125-9
1	J:155532 Ohno M, Hiraoka Y, Matsuoka T, Tomimoto H, Takao K, Miyakawa T, Oshima N, Kiyonari H, Kimura T, Kita T, Nishi E, Nardilysin regulates axonal maturation and myelination in the central and peripheral nervous system. Nat Neurosci. 2009 Dec;12(12):1506-13
1*	J:142504 Park J, Liu B, Chen T, Li H, Hu X, Gao J, Zhu Y, Zhu Q, Qiang B, Yuan J, Peng X, Qiu M, Disruption of Nectin-like 1 cell adhesion molecule leads to delayed axonal myelination in the CNS. J Neurosci. 2008 Nov 26;28(48):12815-9
1	J:331420 Pijuan I, Balducci E, Soto-Sanchez C, Fernandez E, Barallobre MJ, Arbones ML, Impaired macroglial development and axonal conductivity contributes to the neuropathology of DYRK1A-related intellectual disability syndrome. Sci Rep. 2022 Nov 19;12(1):19912
1	J:123227 See J, Mamontov P, Ahn K, Wine-Lee L, Crenshaw EB 3rd, Grinspan JB, BMP signaling mutant mice exhibit glial cell maturation defects. Mol Cell Neurosci. 2007 May;35(1):171-82
1	J:94807 Southwood C, He C, Garbern J, Kamholz J, Arroyo E, Gow A, CNS myelin paranodes require Nkx6-2 homeoprotein transcriptional activity for normal structure. J Neurosci. 2004 Dec 15;24(50):11215-25
1*	J:286891 Sumi K, Uno K, Noike H, Tomohiro T, Hatanaka Y, Furukawa-Hibi Y, Nabeshima T, Miyamoto Y, Nitta A, Behavioral impairment in SHATI/NAT8L knockout mice via dysfunction of myelination development. Sci Rep. 2017 Dec 4;7(1):16872
1	J:273172 Upadhyay A, Hosseinibarkooie S, Schneider S, Kaczmarek A, Torres-Benito L, Mendoza-Ferreira N, Overhoff M, Rombo R, Grysko V, Kye MJ, Kononenko NL, Wirth B, Neurocalcin Delta Knockout Impairs Adult Neurogenesis Whereas Half Reduction Is Not Pathological. Front Mol Neurosci. 2019;12:19
1	J:323376 Vacher CM, Lacaille H, O'Reilly JJ, Salzbank J, Bakalar D, Sebaoui S, Liere P, Clarkson-Paredes C, Sasaki T, Sathyanesan A, Kratimenos P, Ellegood J, Lerch JP, Imamura Y, Popratiloff A, Hashimoto-Torii K, Gallo V, Schumacher M, Penn AA, Placental endocrine function shapes cerebellar development and social behavior. Nat Neurosci. 2021 Oct;24(10):1392-1401
1	J:167894 Vondran MW, Clinton-Luke P, Honeywell JZ, Dreyfus CF, BDNF+/- mice exhibit deficits in oligodendrocyte lineage cells of the basal forebrain. Glia. 2010 May;58(7):848-56
1	J:337816 Wang W, Su L, Ji F, Zhang D, Wang Y, Zhao J, Jiao RD, Zhang M, Huang E, Jiang H, Zhang J, Jiao J, The human FOXM1 homolog promotes basal progenitor cell proliferation and cortical folding in mouse. EMBO Rep. 2022 Feb 3;23(3):e53602
1	J:344239 Wang Y, Wang W, Su L, Ji F, Zhang M, Xie Y, Zhang T, Jiao J, BACH1 changes microglial metabolism and affects astrogenesis during mouse brain development. Dev Cell. 2024 Jan 8;59(1):108-124.e7
1	J:208015 Xiang J, Yang H, Zhao T, Sun M, Xu X, Zhou XF, Li SH, Li XJ, Huntingtin-associated protein 1 regulates postnatal neurogenesis and neurotrophin receptor sorting. J Clin Invest. 2014 Jan 2;124(1):85-98
1*	J:137506 Yoshikawa F, Sato Y, Tohyama K, Akagi T, Hashikawa T, Nagakura-Takagi Y, Sekine Y, Morita N, Baba H, Suzuki Y, Sugano S, Sato A, Furuichi T, Opalin, a transmembrane sialylglycoprotein located in the central nervous system myelin paranodal loop membrane. J Biol Chem. 2008 Jul 25;283(30):20830-40
1	J:320720 Yu Z, Yang Z, Ren G, Wang Y, Luo X, Zhu F, Yu S, Jia L, Chen M, Worley PF, Xiao B, GATOR2 complex-mediated amino acid signaling regulates brain myelination. Proc Natl Acad Sci U S A. 2022 Jan 18;119(3):e2110917119
1	J:347284 Zhang Y, Song Z, Wu R, Kong X, Zhang H, Li S, Gong X, Gong S, Cheng J, Yuan F, Wu H, Wang S, Yuan Z, PRRC2B modulates oligodendrocyte progenitor cell development and myelination by stabilizing Sox2 mRNA. Cell Rep. 2024 Mar 26;43(3):113930
1	J:306852 Zhu H, Meissner LE, Byrnes C, Tuymetova G, Tifft CJ, Proia RL, The Complement Regulator Susd4 Influences Nervous-System Function and Neuronal Morphology in Mice. iScience. 2020 Mar 27;23(3):100957
1	J:168041 Zhu Y, Park J, Hu X, Zheng K, Li H, Cao Q, Feng GS, Qiu M, Control of oligodendrocyte generation and proliferation by Shp2 protein tyrosine phosphatase. Glia. 2010 Sep;58(12):1407-14
1	J:168571 Zou J, Zhou L, Du XX, Ji Y, Xu J, Tian J, Jiang W, Zou Y, Yu S, Gan L, Luo M, Yang Q, Cui Y, Yang W, Xia X, Chen M, Zhao X, Shen Y, Chen PY, Worley PF, Xiao B, Rheb1 is required for mTORC1 and myelination in postnatal brain development. Dev Cell. 2011 Jan 18;20(1):97-108