Gene Expression Literature Summary
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Assay
Age
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Western blot
Postnatal
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| Jun jun proto-oncogene (Synonyms: c-jun, Junc) | |
| Results | Reference |
| 1 | J:343798 Cheng T, Agwu C, Shim K, Wang B, Jain S, Mahjoub MR, Aberrant centrosome biogenesis disrupts nephron and collecting duct progenitor growth and fate resulting in fibrocystic kidney disease. Development. 2023 Dec 15;150(24) |
| 1 | J:248325 Figlia G, Norrmen C, Pereira JA, Gerber D, Suter U, Dual function of the PI3K-Akt-mTORC1 axis in myelination of the peripheral nervous system. Elife. 2017 Sep 07;6:e29241 |
| 1 | J:314870 Gatius A, Tarabal O, Cayuela P, Casanovas A, Piedrafita L, Salvany S, Hernandez S, Soler RM, Esquerda JE, Caldero J, The Y172 Monoclonal Antibody Against p-c-Jun (Ser63) Is a Marker of the Postsynaptic Compartment of C-Type Cholinergic Afferent Synapses on Motoneurons. Front Cell Neurosci. 2019;13:582 |
| 1 | J:302370 Goodwani S, Fernandez C, Acton PJ, Buggia-Prevot V, McReynolds ML, Ma J, Hu CH, Hamby ME, Jiang Y, Le K, Soth MJ, Jones P, Ray WJ, Dual Leucine Zipper Kinase Is Constitutively Active in the Adult Mouse Brain and Has Both Stress-Induced and Homeostatic Functions. Int J Mol Sci. 2020 Jul 9;21(14):4849 |
| 1 | J:95744 Ha HY, Cho IH, Lee KW, Lee KW, Song JY, Kim KS, Yu YM, Lee JK, Song JS, Yang SD, Shin HS, Han PL, The axon guidance defect of the telencephalic commissures of the JSAP1-deficient brain was partially rescued by the transgenic expression of JIP1. Dev Biol. 2005 Jan 1;277(1):184-99 |
| 1 | J:307816 Heymans C, Delcorte O, Spourquet C, Villacorte-Tabelin M, Dupasquier S, Achouri Y, Mahibullah S, Lemoine P, Balda MS, Matter K, Pierreux CE, Spatio-temporal expression pattern and role of the tight junction protein MarvelD3 in pancreas development and function. Sci Rep. 2021 Jul 15;11(1):14519 |
| 1 | J:84743 Li G, Gustafson-Brown C, Hanks SK, Nason K, Arbeit JM, Pogliano K, Wisdom RM, Johnson RS, c-Jun is essential for organization of the epidermal leading edge. Dev Cell. 2003 Jun;4(6):865-77 |
| 1 | J:171254 Matsumoto A, Onoyama I, Sunabori T, Kageyama R, Okano H, Nakayama KI, Fbxw7-dependent Degradation of Notch Is Required for Control of 'Stemness' and Neuronal-Glial Differentiation in Neural Stem Cells. J Biol Chem. 2011 Apr 15;286(15):13754-64 |
| 1 | J:178271 Migliorini D, Bogaerts S, Defever D, Vyas R, Denecker G, Radaelli E, Zwolinska A, Depaepe V, Hochepied T, Skarnes WC, Marine JC, Cop1 constitutively regulates c-Jun protein stability and functions as a tumor suppressor in mice. J Clin Invest. 2011 Apr 1;121(4):1329-43 |
| 1 | J:267072 Newton K, Dugger DL, Sengupta-Ghosh A, Ferrando RE, Chu F, Tao J, Lam W, Haller S, Chan S, Sa S, Dunlap D, Eastham-Anderson J, Ngu H, Hung J, French DM, Webster JD, Bolon B, Liu J, Reja R, Kummerfeld S, Chen YJ, Modrusan Z, Lewcock JW, Dixit VM, Ubiquitin ligase COP1 coordinates transcriptional programs that control cell type specification in the developing mouse brain. Proc Natl Acad Sci U S A. 2018 Oct 30;115(44):11244-11249 |
| 1* | J:137068 Parkinson DB, Bhaskaran A, Arthur-Farraj P, Noon LA, Woodhoo A, Lloyd AC, Feltri ML, Wrabetz L, Behrens A, Mirsky R, Jessen KR, c-Jun is a negative regulator of myelination. J Cell Biol. 2008 May 19;181(4):625-37 |
| 1 | J:317434 Pernot M, Jaspard-Vinassa B, Abelanet A, Rubin S, Forfar I, Jeanningros S, Cetran L, Yu MH, Balse E, Hatem S, Dufourcq P, Couffinhal T, Duplaa C, Decrease of Pdzrn3 is required for heart maturation and protects against heart failure. Sci Rep. 2022 Jan 7;12(1):8 |
| 1 | J:268906 Xie SJ, Li JH, Chen HF, Tan YY, Liu SR, Zhang Y, Xu H, Yang JH, Liu S, Zheng LL, Huang MB, Guo YH, Zhang Q, Zhou H, Qu LH, Inhibition of the JNK/MAPK signaling pathway by myogenesis-associated miRNAs is required for skeletal muscle development. Cell Death Differ. 2018 Sep;25(9):1581-1597 |
| 1 | J:255722 Yamasaki T, Deki-Arima N, Kaneko A, Miyamura N, Iwatsuki M, Matsuoka M, Fujimori-Tonou N, Okamoto-Uchida Y, Hirayama J, Marth JD, Yamanashi Y, Kawasaki H, Yamanaka K, Penninger JM, Shibata S, Nishina H, Age-dependent motor dysfunction due to neuron-specific disruption of stress-activated protein kinase MKK7. Sci Rep. 2017 Aug 4;7(1):7348 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/28/2024 MGI 6.13 |
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