Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Dnmt1  DNA methyltransferase 1   (Synonyms: Cxxc9, Dnmt1o, MommeD2, MTase)
Results	Reference
1	J:203762 Burton A, Muller J, Tu S, Padilla-Longoria P, Guccione E, Torres-Padilla ME, Single-cell profiling of epigenetic modifiers identifies PRDM14 as an inducer of cell fate in the mammalian embryo. Cell Rep. 2013 Nov 14;5(3):687-701
1	J:224084 Elliott EN, Sheaffer KL, Schug J, Stappenbeck TS, Kaestner KH, Dnmt1 is essential to maintain progenitors in the perinatal intestinal epithelium. Development. 2015 Jun 15;142(12):2163-72
1*	J:140465 Guo G, Huss M, Tong GQ, Wang C, Li Sun L, Clarke ND, Robson P, Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. Dev Cell. 2010 Apr 20;18(4):675-85
1	J:93248 Hamatani T, Falco G, Carter MG, Akutsu H, Stagg CA, Sharov AA, Dudekula DB, VanBuren V, Ko MS, Age-associated alteration of gene expression patterns in mouse oocytes. Hum Mol Genet. 2004 Nov 1;13(19):2263-78
1	J:259618 Hatazawa Y, Ono Y, Hirose Y, Kanai S, Fujii NL, Machida S, Nishino I, Shimizu T, Okano M, Kamei Y, Ogawa Y, Reduced Dnmt3a increases Gdf5 expression with suppressed satellite cell differentiation and impaired skeletal muscle regeneration. FASEB J. 2018 Mar;32(3):1452-1467
1	J:264903 Hoang TV, Horowitz ER, Chaffee BR, Qi P, Flake RE, Bruney DG, Rasor BJ, Rosalez SE, Wagner BD, Robinson ML, Lens development requires DNMT1 but takes place normally in the absence of both DNMT3A and DNMT3B activity. Epigenetics. 2017 Jan 2;12(1):27-40
1	J:314906 Khang R, Jo A, Kang H, Kim H, Kwag E, Lee JY, Koo O, Park J, Kim HK, Jo DG, Hwang I, Ahn JY, Lee Y, Choi JY, Lee YS, Shin JH, Loss of zinc-finger protein 212 leads to Purkinje cell death and locomotive abnormalities with phospholipase D3 downregulation. Sci Rep. 2021 Nov 23;11(1):22745
1	J:169234 Kim JD, Kim H, Ekram MB, Yu S, Faulk C, Kim J, Rex1/Zfp42 as an epigenetic regulator for genomic imprinting. Hum Mol Genet. 2011 Apr 1;20(7):1353-62
1	J:92186 La Salle S, Mertineit C, Taketo T, Moens PB, Bestor TH, Trasler JM, Windows for sex-specific methylation marked by DNA methyltransferase expression profiles in mouse germ cells. Dev Biol. 2004 Apr 15;268(2):403-15
1	J:131948 Liu L, Bailey SM, Okuka M, Munoz P, Li C, Zhou L, Wu C, Czerwiec E, Sandler L, Seyfang A, Blasco MA, Keefe DL, Telomere lengthening early in development. Nat Cell Biol. 2007 Dec;9(12):1436-41
1*	J:104974 MacDonald JL, Gin CS, Roskams AJ, Stage-specific induction of DNA methyltransferases in olfactory receptor neuron development. Dev Biol. 2005 Dec 15;288(2):461-73
1	J:306136 Manti M, Pui HP, Edstrom S, Risal S, Lu H, Lindgren E, Ohlsson C, Jerlhag E, Benrick A, Deng Q, Stener-Victorin E, Excess of ovarian nerve growth factor impairs embryonic development and causes reproductive and metabolic dysfunction in adult female mice. FASEB J. 2020 Nov;34(11):14440-14457
1*	J:46642 Mertineit C, Yoder JA, Taketo T, Laird DW, Trasler JM, Bestor TH, Sex-specific exons control DNA methyltransferase in mammalian germ cells. Development. 1998 Mar;125(5):889-97
1	J:180117 Nasonkin IO, Lazo K, Hambright D, Brooks M, Fariss R, Swaroop A, Distinct nuclear localization patterns of DNA methyltransferases in developing and mature mammalian retina. J Comp Neurol. 2011 Jul 1;519(10):1914-30
1	J:92421 Rajkovic A, Pangas SA, Ballow D, Suzumori N, Matzuk MM, NOBOX deficiency disrupts early folliculogenesis and oocyte-specific gene expression. Science. 2004 Aug 20;305(5687):1157-9
1	J:76510 Ratnam S, Mertineit C, Ding F, Howell CY, Clarke HJ, Bestor TH, Chaillet JR, Trasler JM, Dynamics of Dnmt1 methyltransferase expression and intracellular localization during oogenesis and preimplantation development. Dev Biol. 2002 May 15;245(2):304-14
1	J:312335 Reyes-Aguirre LI, Lamas M, Oct4 Methylation-Mediated Silencing As an Epigenetic Barrier Preventing Muller Glia Dedifferentiation in a Murine Model of Retinal Injury. Front Neurosci. 2016;10:523
1	J:213445 Rutledge CE, Lau HT, Mangan H, Hardy LL, Sunnotel O, Guo F, MacNicol AM, Walsh CP, Lees-Murdock DJ, Efficient translation of Dnmt1 requires cytoplasmic polyadenylation and Musashi binding elements. PLoS One. 2014;9(2):e88385
1	J:279154 Shen J, Wang C, Li D, Xu T, Myers J, Ashton JM, Wang T, Zuscik MJ, McAlinden A, O'Keefe RJ, DNA methyltransferase 3b regulates articular cartilage homeostasis by altering metabolism. JCI Insight. 2017 Jun 15;2(12)
1	J:345314 Vukic M, Chouaref J, Della Chiara V, Dogan S, Ratner F, Hogenboom JZM, Epp TA, Chawengsaksophak K, Vonk KKD, Breukel C, Ariyurek Y, San Leon Granado D, Kloet SL, Daxinger L, CDCA7-associated global aberrant DNA hypomethylation translates to localized, tissue-specific transcriptional responses. Sci Adv. 2024 Feb 9;10(6):eadk3384
1	J:310870 Wang W, Zhao X, Shao Y, Duan X, Wang Y, Li J, Li J, Li D, Li X, Wong J, Mutation-induced DNMT1 cleavage drives neurodegenerative disease. Sci Adv. 2021 Sep 3;7(36):eabe8511
1*	J:330334 Zhang H, Jiang JC, Wu YW, Yu YS, Wang HN, Ding NZ, Fan HY, The RNA ligase RNA terminal phosphate cyclase B regulates mRNA alternative splicing and is required for mouse oocyte development and maintenance. Development. 2022 Oct 1;149(19):dev200497