Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Dyrk1a  dual-specificity tyrosine phosphorylation regulated kinase 1a   (Synonyms: 2310043O08Rik, D16Ertd272e, D16Ertd493e, Dyrk, Mnbh)
Results	Reference
1	J:311493 Brault V, Nguyen TL, Flores-Gutierrez J, Iacono G, Birling MC, Lalanne V, Meziane H, Manousopoulou A, Pavlovic G, Lindner L, Selloum M, Sorg T, Yu E, Garbis SD, Herault Y, Dyrk1a gene dosage in glutamatergic neurons has key effects in cognitive deficits observed in mouse models of MRD7 and Down syndrome. PLoS Genet. 2021 Sep;17(9):e1009777
1*	J:67406 Geiger JN, Knudsen GT, Panek L, Pandit AK, Yoder MD, Lord KA, Creasy CL, Burns BM, Gaines P, Dillon SB, Wojchowski DM, mDYRK3 kinase is expressed selectively in late erythroid progenitor cells and attenuates colony-forming unit-erythroid development. Blood. 2001 Feb 15;97(4):901-10
1*	J:80501 Gitton Y, Dahmane N, Baik S, Ruiz I Altaba A, Neidhardt L, Scholze M, Herrmann BG, Kahlem P, Benkahla A, Schrinner S, Yildirimman R, Herwig R, Lehrach H, Yaspo ML, A gene expression map of human chromosome 21 orthologues in the mouse. Nature. 2002 Dec 5;420(6915):586-90
1	J:182294 Guedj F, Pereira PL, Najas S, Barallobre MJ, Chabert C, Souchet B, Sebrie C, Verney C, Herault Y, Arbones M, Delabar JM, DYRK1A: A master regulatory protein controlling brain growth. Neurobiol Dis. 2012 Apr;46(1):190-203
1	J:343255 Hawley LE, Stringer M, Deal AJ, Folz A, Goodlett CR, Roper RJ, Sex-specific developmental alterations in DYRK1A expression in the brain of a Down syndrome mouse model. Neurobiol Dis. 2023 Nov 20;190:106359
1	J:221510 Kariyawasam D, Rachdi L, Carre A, Martin M, Houlier M, Janel N, Delabar JM, Scharfmann R, Polak M, DYRK1A BAC transgenic mouse: a new model of thyroid dysgenesis in Down syndrome. Endocrinology. 2015 Mar;156(3):1171-80
1	J:146836 Lepagnol-Bestel AM, Zvara A, Maussion G, Quignon F, Ngimbous B, Ramoz N, Imbeaud S, Loe-Mie Y, Benihoud K, Agier N, Salin PA, Cardona A, Khung-Savatovsky S, Kallunki P, Delabar JM, Puskas LG, Delacroix H, Aggerbeck L, Delezoide AL, Delattre O, Gorwood P,Moalic JM, Simonneau M, DYRK1A interacts with the REST/NRSF-SWI/SNF chromatin remodelling complex to deregulate gene clusters involved in the neuronal phenotypic traits of Down syndrome. Hum Mol Genet. 2009 Apr 15;18(8):1405-14
1	J:240247 Notwell JH, Heavner WE, Darbandi SF, Katzman S, McKenna WL, Ortiz-Londono CF, Tastad D, Eckler MJ, Rubenstein JL, McConnell SK, Chen B, Bejerano G, TBR1 regulates autism risk genes in the developing neocortex. Genome Res. 2016 Aug;26(8):1013-22
1	J:210093 Rachdi L, Kariyawasam D, Guez F, Aiello V, Arbones ML, Janel N, Delabar JM, Polak M, Scharfmann R, Dyrk1a haploinsufficiency induces diabetes in mice through decreased pancreatic beta cell mass. Diabetologia. 2014 May;57(5):960-9
1*	J:80502 Reymond A, Marigo V, Yaylaoglu MB, Leoni A, Ucla C, Scamuffa N, Caccioppoli C, Dermitzakis ET, Lyle R, Banfi S, Eichele G, Antonarakis SE, Ballabio A, Human chromosome 21 gene expression atlas in the mouse. Nature. 2002 Dec 5;420(6915):582-6
1*	J:37711 Song WJ, Sternberg LR, Kasten-Sportes C, Keuren ML, Chung SH, Slack AC, Miller DE, Glover TW, Chiang PW, Lou L, Kurnit DM, Isolation of human and murine homologues of the Drosophila minibrain gene: human homologue maps to 21q22.2 in the Down syndrome critical region. Genomics. 1996 Dec 15;38(3):331-9
1*	J:319245 Wang P, Wang L, Chen L, Sun X, Dual-specificity tyrosine-phosphorylation regulated kinase 1A Gene Transcription is regulated by Myocyte Enhancer Factor 2D. Sci Rep. 2017 Aug 3;7(1):7240