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Gene Expression Literature Summary
Assay
Age
RT-PCR
Postnatal

16 matching records from 16 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Dio3  deiodinase, iodothyronine type III  
Results  Reference
1J:182286 Charalambous M, Ferron SR, da Rocha ST, Murray AJ, Rowland T, Ito M, Schuster-Gossler K, Hernandez A, Ferguson-Smith AC, Imprinted gene dosage is critical for the transition to independent life. Cell Metab. 2012 Feb 8;15(2):209-21
1J:124897 Dentice M, Luongo C, Huang S, Ambrosio R, Elefante A, Mirebeau-Prunier D, Zavacki AM, Fenzi G, Grachtchouk M, Hutchin M, Dlugosz AA, Bianco AC, Missero C, Larsen PR, Salvatore D, Sonic hedgehog-induced type 3 deiodinase blocks thyroid hormone action enhancing proliferation of normal and malignant keratinocytes. Proc Natl Acad Sci U S A. 2007 Sep 4;104(36):14466-71
1*J:201184 Ferrara AM, Liao XH, Gil-Ibanez P, Marcinkowski T, Bernal J, Weiss RE, Dumitrescu AM, Refetoff S, Changes in thyroid status during perinatal development of MCT8-deficient male mice. Endocrinology. 2013 Jul;154(7):2533-41
1J:227474 Fonseca TL, Fernandes GW, McAninch EA, Bocco BM, Abdalla SM, Ribeiro MO, Mohacsik P, Fekete C, Li D, Xing X, Wang T, Gereben B, Bianco AC, Perinatal deiodinase 2 expression in hepatocytes defines epigenetic susceptibility to liver steatosis and obesity. Proc Natl Acad Sci U S A. 2015 Nov 10;112(45):14018-23
1J:324530 Fonseca TL, Russo SC, Luongo C, Salvatore D, Bianco AC, Inactivation of Type 3 Deiodinase Results in Life-long Changes in the Brown Adipose Tissue Transcriptome in the Male Mouse. Endocrinology. 2022 May 1;163(5)
1J:303008 Ignacio DL, Silvestre DH, Anne-Palmer E, Bocco BM, Fonseca TL, Ribeiro MO, Gereben B, Bianco AC, Werneck-de-Castro JP, Early Developmental Disruption of Type 2 Deiodinase Pathway in Mouse Skeletal Muscle Does Not Impair Muscle Function. Thyroid. 2017 Apr;27(4):577-586
1J:216177 Labialle S, Marty V, Bortolin-Cavaille ML, Hoareau-Osman M, Pradere JP, Valet P, Martin PG, Cavaille J, The miR-379/miR-410 cluster at the imprinted Dlk1-Dio3 domain controls neonatal metabolic adaptation. EMBO J. 2014 Oct 1;33(19):2216-30
1J:132025 Labialle S, Yang L, Ruan X, Villemain A, Schmidt JV, Hernandez A, Wiltshire T, Cermakian N, Naumova AK, Coordinated diurnal regulation of genes from the Dlk1-Dio3 imprinted domain: implications for regulation of clusters of non-paralogous genes. Hum Mol Genet. 2008 Jan 1;17(1):15-26
1J:218428 Martinez ME, Charalambous M, Saferali A, Fiering S, Naumova AK, St Germain D, Ferguson-Smith AC, Hernandez A, Genomic imprinting variations in the mouse type 3 deiodinase gene between tissues and brain regions. Mol Endocrinol. 2014 Nov;28(11):1875-86
1J:177060 Medina MC, Molina J, Gadea Y, Fachado A, Murillo M, Simovic G, Pileggi A, Hernandez A, Edlund H, Bianco AC, The Thyroid Hormone-Inactivating Type III Deiodinase Is Expressed in Mouse and Human {beta}-Cells and Its Targeted Inactivation Impairs Insulin Secretion. Endocrinology. 2011 Oct;152(10):3717-27
1*J:208718 Selmi-Ruby S, Bouazza L, Obregon MJ, Conscience A, Flamant F, Samarut J, Borson-Chazot F, Rousset B, The targeted inactivation of TRbeta gene in thyroid follicular cells suggests a new mechanism of regulation of thyroid hormone production. Endocrinology. 2014 Feb;155(2):635-46
1*J:147577 Takahashi N, Okamoto A, Kobayashi R, Shirai M, Obata Y, Ogawa H, Sotomaru Y, Kono T, Deletion of Gtl2, imprinted non-coding RNA, with its differentially methylated region induces lethal parent-origin-dependent defects in mice. Hum Mol Genet. 2009 May 15;18(10):1879-88
1J:78148 Tsai CE, Lin SP, Ito M, Takagi N, Takada S, Ferguson-Smith AC, Genomic imprinting contributes to thyroid hormone metabolism in the mouse embryo. Curr Biol. 2002 Jul 23;12(14):1221-6
1J:207929 Yamaguchi S, Shen L, Liu Y, Sendler D, Zhang Y, Role of Tet1 in erasure of genomic imprinting. Nature. 2013 Dec 19;504(7480):460-4
1J:346630 Zhang X, He H, Yu H, Teng X, Wang Z, Li C, Li J, Yang H, Shen J, Wu T, Zhang F, Zhang Y, Wu Q, Maternal RNA transcription in Dlk1-Dio3 domain is critical for proper development of the mouse placental vasculature. Commun Biol. 2024 Mar 23;7(1):363
1J:281273 Zhu W, Botticelli EM, Kery RE, Mao Y, Wang X, Yang A, Wang X, Zhou J, Zhang X, Soberman RJ, Klibanski A, Zhou Y, Meg3-DMR, not the Meg3 gene, regulates imprinting of the Dlk1-Dio3 locus. Dev Biol. 2019 Nov 1;455(1):10-18

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory