Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Jag1  jagged 1   (Synonyms: ABE2, Gsfabe2, Headturner, Htu, Ozz, Serrate-1)
Results	Reference
1	J:251150 Aoki H, Ogino H, Tomita H, Hara A, Kunisada T, Disruption of Rest Leads to the Early Onset of Cataracts with the Aberrant Terminal Differentiation of Lens Fiber Cells. PLoS One. 2016;11(9):e0163042
1	J:249355 Bicker F, Vasic V, Horta G, Ortega F, Nolte H, Kavyanifar A, Keller S, Stankovic ND, Harter PN, Benedito R, Lutz B, Bauerle T, Hartwig J, Baumgart J, Kruger M, Radyushkin K, Alberi L, Berninger B, Schmidt MHH, Neurovascular EGFL7 regulates adult neurogenesis in the subventricular zone and thereby affects olfactory perception. Nat Commun. 2017 Jun 28;8:15922
1	J:185338 Boucherat O, Chakir J, Jeannotte L, The loss of Hoxa5 function promotes Notch-dependent goblet cell metaplasia in lung airways. Biol Open. 2012;q:677-691
1	J:164021 Bremer J, O'Connor T, Tiberi C, Rehrauer H, Weis J, Aguzzi A, Ablation of Dicer from murine Schwann cells increases their proliferation while blocking myelination. PLoS One. 2010;5(8):e12450
1	J:310741 Briot A, Jaroszewicz A, Warren CM, Lu J, Touma M, Rudat C, Hofmann JJ, Airik R, Weinmaster G, Lyons K, Wang Y, Kispert A, Pellegrini M, Iruela-Arispe ML, Repression of Sox9 by Jag1 is continuously required to suppress the default chondrogenic fate of vascular smooth muscle cells. Dev Cell. 2014 Dec 22;31(6):707-21
1	J:108618 Carson C, Murdoch B, Roskams AJ, Notch 2 and Notch 1/3 segregate to neuronal and glial lineages of the developing olfactory epithelium. Dev Dyn. 2006 Jun;235(6):1678-88
1	J:224823 Chen AC, Donovan A, Ned-Sykes R, Andrews NC, Noncanonical role of transferrin receptor 1 is essential for intestinal homeostasis. Proc Natl Acad Sci U S A. 2015 Sep 15;112(37):11714-9
1	J:206194 Corada M, Orsenigo F, Morini MF, Pitulescu ME, Bhat G, Nyqvist D, Breviario F, Conti V, Briot A, Iruela-Arispe ML, Adams RH, Dejana E, Sox17 is indispensable for acquisition and maintenance of arterial identity. Nat Commun. 2013;4:2609
1*	J:93160 Cormier S, Vandormael-Pournin S, Babinet C, Cohen-Tannoudji M, Developmental expression of the Notch signaling pathway genes during mouse preimplantation development. Gene Expr Patterns. 2004 Oct;4(6):713-7
1	J:271384 D'Amato G, Luxan G, del Monte-Nieto G, Martinez-Poveda B, Torroja C, Walter W, Bochter MS, Benedito R, Cole S, Martinez F, Hadjantonakis AK, Uemura A, Jimenez-Borreguero LJ, de la Pompa JL, Sequential Notch activation regulates ventricular chamber development. Nat Cell Biol. 2016 Jan;18(1):7-20
1	J:131874 Di-Poi N, Zakany J, Duboule D, Distinct Roles and Regulations for Hoxd Genes in Metanephric Kidney Development. PLoS Genet. 2007 Dec 21;3(12):e232
1	J:257440 Dvoriantchikova G, Tao W, Pappas S, Gaidosh G, Tse DT, Ivanov D, Pelaez D, Molecular Profiling of the Developing Lacrimal Gland Reveals Putative Role of Notch Signaling in Branching Morphogenesis. Invest Ophthalmol Vis Sci. 2017 Feb 1;58(2):1098-1109
1	J:143603 Esibizione D, Cui CY, Schlessinger D, Candidate EDA targets revealed by expression profiling of primary keratinocytes from Tabby mutant mice. Gene. 2008 Dec 31;427(1-2):42-6
1	J:218171 Falix FA, Weeda VB, Labruyere WT, Poncy A, de Waart DR, Hakvoort TB, Lemaigre F, Gaemers IC, Aronson DC, Lamers WH, Hepatic Notch2 deficiency leads to bile duct agenesis perinatally and secondary bile duct formation after weaning. Dev Biol. 2014 Dec 15;396(2):201-13
1	J:56675 Felli MP, Maroder M, Mitsiadis TA, Campese AF, Bellavia D, Vacca A, Mann RS, Frati L, Lendahl U, Gulino A, Screpanti I, Expression pattern of notch1, 2 and 3 and Jagged1 and 2 in lymphoid and stromal thymus components: distinct ligand-receptor interactions in intrathymic T cell development. Int Immunol. 1999 Jul;11(7):1017-25
1	J:307272 Godin P, Tsoi M, Paquet M, Boerboom D, YAP and TAZ are required for the postnatal development and the maintenance of the structural integrity of the oviduct. Reproduction. 2020 Aug;160(2):307-318
1*	J:152922 Golson ML, Le Lay J, Gao N, Bramswig N, Loomes KM, Oakey R, May CL, White P, Kaestner KH, Jagged1 is a competitive inhibitor of Notch signaling in the embryonic pancreas. Mech Dev. 2009 Aug-Sep;126(8-9):687-99
1*	J:187652 Guo M, Zhang H, Bian F, Li G, Mu X, Wen J, Mao G, Teng Z, Xia G, Zhang M, P4 down-regulates Jagged2 and Notch1 expression during primordial folliculogenesis. Front Biosci (Elite Ed). 2012 Jun 1;4:2631-44
1	J:251433 Ha T, Moon KH, Dai L, Hatakeyama J, Yoon K, Park HS, Kong YY, Shimamura K, Kim JW, The Retinal Pigment Epithelium Is a Notch Signaling Niche in the Mouse Retina. Cell Rep. 2017 Apr 11;19(2):351-363
1	J:96967 Hahn KL, Johnson J, Beres BJ, Howard S, Wilson-Rawls J, Lunatic fringe null female mice are infertile due to defects in meiotic maturation. Development. 2005 Feb;132(4):817-28
1	J:235665 He S, Limi S, McGreal RS, Xie Q, Brennan LA, Kantorow WL, Kokavec J, Majumdar R, Hou H Jr, Edelmann W, Liu W, Ashery-Padan R, Zavadil J, Kantorow M, Skoultchi AI, Stopka T, Cvekl A, Chromatin remodeling enzyme Snf2h regulates embryonic lens differentiation and denucleation. Development. 2016 Jun 1;143(11):1937-47
1	J:294650 Hemker SL, Cerqueira DM, Bodnar AJ, Cargill KR, Clugston A, Anslow MJ, Sims-Lucas S, Kostka D, Ho J, Deletion of hypoxia-responsive microRNA-210 results in a sex-specific decrease in nephron number. FASEB J. 2020 Apr;34(4):5782-5799
1	J:189213 Hofmann JJ, Briot A, Enciso J, Zovein AC, Ren S, Zhang ZW, Radtke F, Simons M, Wang Y, Iruela-Arispe ML, Endothelial deletion of murine Jag1 leads to valve calcification and congenital heart defects associated with Alagille syndrome. Development. 2012 Dec;139(23):4449-60
1	J:59312 Jensen J, Pedersen EE, Galante P, Hald J, Heller RS, Ishibashi M, Kageyama R, Guillemot F, Serup P, Madsen OD, Control of endodermal endocrine development by Hes-1. Nat Genet. 2000 Jan;24(1):36-44
1	J:95098 Kodama Y, Hijikata M, Kageyama R, Shimotohno K, Chiba T, The role of notch signaling in the development of intrahepatic bile ducts. Gastroenterology. 2004 Dec;127(6):1775-86
1	J:96080 Kong Y, Glickman J, Subramaniam M, Shahsafaei A, Allamneni KP, Aster JC, Sklar J, Sunday ME, Functional diversity of notch family genes in fetal lung development. Am J Physiol Lung Cell Mol Physiol. 2004 May;286(5):L1075-83
1*	J:51632 Lewis AK, Frantz GD, Carpenter DA, de Sauvage FJ, Gao WQ, Distinct expression patterns of notch family receptors and ligands during development of the mammalian inner ear. Mech Dev. 1998 Nov;78(1-2):159-63
1*	J:79434 Loomes KM, Taichman DB, Glover CL, Williams PT, Markowitz JE, Piccoli DA, Baldwin HS, Oakey RJ, Characterization of Notch receptor expression in the developing mammalian heart and liver. Am J Med Genet. 2002 Oct 1;112(2):181-9
1*	J:58809 Loomes KM, Underkoffler LA, Morabito J, Gottlieb S, Piccoli DA, Spinner NB, Baldwin HS, Oakey RJ, The expression of Jagged1 in the developing mammalian heart correlates with cardiovascular disease in Alagille syndrome. Hum Mol Genet. 1999 Dec;8(13):2443-9
1*	J:192269 Mukhopadhyay A, Krishnaswami SR, Cowing-Zitron C, Hung NJ, Reilly-Rhoten H, Burns J, Yu BD, Negative regulation of Shh levels by Kras and Fgfr2 during hair follicle development. Dev Biol. 2013 Jan 15;373(2):373-82
1	J:214133 Nantie LB, Himes AD, Getz DR, Raetzman LT, Notch signaling in postnatal pituitary expansion: proliferation, progenitors, and cell specification. Mol Endocrinol. 2014 May;28(5):731-44
1	J:229930 Nechiporuk T, McGann J, Mullendorff K, Hsieh J, Wurst W, Floss T, Mandel G, The REST remodeling complex protects genomic integrity during embryonic neurogenesis. Elife. 2016;5:e09584
1	J:146853 Oikawa T, Kamiya A, Kakinuma S, Zeniya M, Nishinakamura R, Tajiri H, Nakauchi H, Sall4 regulates cell fate decision in fetal hepatic stem/progenitor cells. Gastroenterology. 2009 Mar;136(3):1000-11
1	J:173578 Parker MA, Jiang K, Kempfle JS, Mizutari K, Simmons CL, Bieber R, Adams J, Edge AS, TAK1 Expression in the Cochlea: A Specific Marker for Adult Supporting Cells. J Assoc Res Otolaryngol. 2011 Aug;12(4):471-83
1	J:323229 Rosendahl AH, Monnius M, Laitala A, Railo A, Miinalainen I, Heljasvaara R, Maki JM, Myllyharju J, Deletion of hypoxia-inducible factor prolyl 4-hydroxylase 2 in FoxD1-lineage mesenchymal cells leads to congenital truncal alopecia. J Biol Chem. 2022 Mar 2;298(4):101787
1	J:330449 Rusidze M, Faure MC, Sicard P, Raymond-Letron I, Giton F, Vessieres E, Prevot V, Henrion D, Arnal JF, Cornil CA, Lenfant F, Loss of function of the maternal membrane oestrogen receptor ERalpha alters expansion of trophoblast cells and impacts mouse fertility. Development. 2022 Oct 1;149(19):dev200683
1*	J:87397 Sumazaki R, Shiojiri N, Isoyama S, Masu M, Keino-Masu K, Osawa M, Nakauchi H, Kageyama R, Matsui A, Conversion of biliary system to pancreatic tissue in Hes1-deficient mice. Nat Genet. 2004 Jan;36(1):83-7
1	J:79222 Taichman DB, Loomes KM, Schachtner SK, Guttentag S, Vu C, Williams P, Oakey RJ, Baldwin HS, Notch1 and Jagged1 expression by the developing pulmonary vasculature. Dev Dyn. 2002 Oct;225(2):166-75
1	J:236406 Takada Y, Fukuda A, Chiba T, Seno H, Brg1 plays an essential role in development and homeostasis of the duodenum through regulation of Notch signaling. Development. 2016 Oct 1;143(19):3532-3539
1	J:91008 Tanimizu N, Miyajima A, Notch signaling controls hepatoblast differentiation by altering the expression of liver-enriched transcription factors. J Cell Sci. 2004 Jul 1;117(Pt 15):3165-74
1	J:175774 Tsao PN, Wei SC, Wu MF, Huang MT, Lin HY, Lee MC, Lin KM, Wang IJ, Kaartinen V, Yang LT, Cardoso WV, Notch signaling prevents mucous metaplasia in mouse conducting airways during postnatal development. Development. 2011 Aug;138(16):3533-43
1	J:213069 Vanorny DA, Prasasya RD, Chalpe AJ, Kilen SM, Mayo KE, Notch signaling regulates ovarian follicle formation and coordinates follicular growth. Mol Endocrinol. 2014 Apr;28(4):499-511
1	J:263687 Wang CX, Cui GS, Liu X, Xu K, Wang M, Zhang XX, Jiang LY, Li A, Yang Y, Lai WY, Sun BF, Jiang GB, Wang HL, Tong WM, Li W, Wang XJ, Yang YG, Zhou Q, METTL3-mediated m6A modification is required for cerebellar development. PLoS Biol. 2018 Jun;16(6):e2004880
1	J:295894 Wei G, Gao N, Chen J, Fan L, Zeng Z, Gao G, Li L, Fang G, Hu K, Pang X, Fan HY, Clevers H, Liu M, Zhang X, Li D, Erk and MAPK signaling is essential for intestinal development through Wnt pathway modulation. Development. 2020 Sep 2;147(17):dev185678
1	J:212272 Wu J, Bao J, Kim M, Yuan S, Tang C, Zheng H, Mastick GS, Xu C, Yan W, Two miRNA clusters, miR-34b/c and miR-449, are essential for normal brain development, motile ciliogenesis, and spermatogenesis. Proc Natl Acad Sci U S A. 2014 Jul 15;111(28):E2851-7
1	J:327590 Xia S, Menden HL, Townley N, Mabry SM, Johnston J, Nyp MF, Heruth DP, Korfhagen T, Sampath V, Delta-like 4 is required for pulmonary vascular arborization and alveolarization in the developing lung. JCI Insight. 2021 Apr 8;6(7)
1	J:119916 Yang HS, Hinds PW, pRb-mediated control of epithelial cell proliferation and Indian hedgehog expression in mouse intestinal development. BMC Dev Biol. 2007;7:6
1	J:152966 Zhao X, D' Arca D, Lim WK, Brahmachary M, Carro MS, Ludwig T, Cardo CC, Guillemot F, Aldape K, Califano A, Iavarone A, Lasorella A, The N-Myc-DLL3 Cascade Is Suppressed by the Ubiquitin Ligase Huwe1 to Inhibit Proliferation and Promote Neurogenesis in the Developing Brain. Dev Cell. 2009 Aug;17(2):210-21
1	J:148015 Zong Y, Panikkar A, Xu J, Antoniou A, Raynaud P, Lemaigre F, Stanger BZ, Notch signaling controls liver development by regulating biliary differentiation. Development. 2009 May;136(10):1727-39