Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Afp  alpha fetoprotein   (Synonyms: alpha-foetoprotein)
Results	Reference
1	J:228779 Alpern D, Langer D, Ballester B, Le Gras S, Romier C, Mengus G, Davidson I, TAF4, a subunit of transcription factor II D, directs promoter occupancy of nuclear receptor HNF4A during post-natal hepatocyte differentiation. Elife. 2014;3:e03613
1	J:61931 Beppu H, Kawabata M, Hamamoto T, Chytil A, Minowa O, Noda T, Miyazono K, BMP type II receptor is required for gastrulation and early development of mouse embryos. Dev Biol. 2000 May 1;221(1):249-58
1*	J:152099 Bi Y, Huang J, He Y, Zhu GH, Su Y, He BC, Luo J, Wang Y, Kang Q, Luo Q, Chen L, Zuo GW, Jiang W, Liu B, Shi Q, Tang M, Zhang BQ, Weng Y, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells. J Cell Biochem. 2009 Jun 26;108(1):295-303
1	J:317045 Cheng W, Li HL, Xi SY, Zhang XF, Zhu Y, Le Xing, Mo YX, Li MM, Kong FE, Zhu WJ, Chen XG, Cui HQ, Cao ZM, Gong YF, Tang YQ, Zhang Y, Guan XY, Ma NF, Liu M, Growth differentiation factor 1-induced tumour plasticity provides a therapeutic window for immunotherapy in hepatocellular carcinoma. Nat Commun. 2021 Dec 8;12(1):7142
1	J:256166 Creasy KT, Jiang J, Ren H, Peterson ML, Spear BT, Zinc Fingers and Homeoboxes 2 (Zhx2) Regulates Sexually Dimorphic Cyp Gene Expression in the Adult Mouse Liver. Gene Expr. 2016;17(1):7-17
1	J:305124 Czepukojc B, Abuhaliema A, Barghash A, Tierling S, Nass N, Simon Y, Korbel C, Cadenas C, van Hul N, Sachinidis A, Hengstler JG, Helms V, Laschke MW, Walter J, Haybaeck J, Leclercq I, Kiemer AK, Kessler SM, IGF2 mRNA Binding Protein 2 Transgenic Mice Are More Prone to Develop a Ductular Reaction and to Progress Toward Cirrhosis. Front Med (Lausanne). 2019;6:179
1	J:243698 Decaens T, Godard C, de Reynies A, Rickman DS, Tronche F, Couty JP, Perret C, Colnot S, Stabilization of beta-catenin affects mouse embryonic liver growth and hepatoblast fate. Hepatology. 2008 Jan;47(1):247-58
1*	J:79500 Gabant P, Forrester L, Nichols J, Van Reeth T, De Mees C, Pajack B, Watt A, Smitz J, Alexandre H, Szpirer C, Szpirer J, Alpha-fetoprotein, the major fetal serum protein, is not essential for embryonic development but is required for female fertility. Proc Natl Acad Sci U S A. 2002 Oct 1;99(20):12865-70
1*	J:228828 Hamazaki J, Hirayama S, Murata S, Redundant Roles of Rpn10 and Rpn13 in Recognition of Ubiquitinated Proteins and Cellular Homeostasis. PLoS Genet. 2015 Jul;11(7):e1005401
1	J:173543 Harper J, Mould A, Andrews RM, Bikoff EK, Robertson EJ, The transcriptional repressor Blimp1/Prdm1 regulates postnatal reprogramming of intestinal enterocytes. Proc Natl Acad Sci U S A. 2011 Jun 28;108(26):10585-90
1*	J:159513 Huang J, Bi Y, Zhu GH, He Y, Su Y, He BC, Wang Y, Kang Q, Chen L, Zuo GW, Luo Q, Shi Q, Zhang BQ, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Retinoic acid signalling induces the differentiation of mouse fetal liver-derived hepatic progenitor cells. Liver Int. 2009 Nov;29(10):1569-81
1*	J:242505 Jiang J, Creasy KT, Purnell J, Peterson ML, Spear BT, Zhx2 (zinc fingers and homeoboxes 2) regulates major urinary protein gene expression in the mouse liver. J Biol Chem. 2017 Apr 21;292(16):6765-6774
1*	J:89458 Jochheim A, Hillemann T, Kania G, Scharf J, Attaran M, Manns MP, Wobus AM, Ott M, Quantitative gene expression profiling reveals a fetal hepatic phenotype of murine ES-derived hepatocytes. Int J Dev Biol. 2004 Feb;48(1):23-9
1*	J:288474 Karagianni P, Moulos P, Schmidt D, Odom DT, Talianidis I, Bookmarking by Non-pioneer Transcription Factors during Liver Development Establishes Competence for Future Gene Activation. Cell Rep. 2020 Feb 4;30(5):1319-1328.e6
1	J:95098 Kodama Y, Hijikata M, Kageyama R, Shimotohno K, Chiba T, The role of notch signaling in the development of intrahepatic bile ducts. Gastroenterology. 2004 Dec;127(6):1775-86
1*	J:181881 Lee JS, Ward WO, Knapp G, Ren H, Vallanat B, Abbott B, Ho K, Karp SJ, Corton JC, Transcriptional ontogeny of the developing liver. BMC Genomics. 2012;13:33
1*	J:254519 Li G, Ji T, Chen J, Fu Y, Hou L, Feng Y, Zhang T, Song T, Zhao J, Endo Y, Lin H, Cai X, Cang Y, CRL4(DCAF8) Ubiquitin Ligase Targets Histone H3K79 and Promotes H3K9 Methylation in the Liver. Cell Rep. 2017 Feb 7;18(6):1499-1511
1*	J:146970 Li T, Huang J, Jiang Y, Zeng Y, He F, Zhang MQ, Han Z, Zhang X, Multi-stage analysis of gene expression and transcription regulation in C57/B6 mouse liver development. Genomics. 2009 Mar;93(3):235-42
1*	J:302850 Liu M, Chen L, Ma NF, Chow RK, Li Y, Song Y, Chan TH, Fang S, Yang X, Xi S, Jiang L, Li Y, Zeng TT, Li Y, Yuan YF, Guan XY, CHD1L promotes lineage reversion of hepatocellular carcinoma through opening chromatin for key developmental transcription factors. Hepatology. 2016 May;63(5):1544-59
1*	J:94197 Long L, Spear BT, FoxA proteins regulate H19 endoderm enhancer E1 and exhibit developmental changes in enhancer binding in vivo. Mol Cell Biol. 2004 Nov;24(21):9601-9
1*	J:154021 Naidu S, Peterson ML, Spear BT, Alpha-fetoprotein related gene (ARG): a new member of the albumin gene family that is no longer functional in primates. Gene. 2010 Jan 1;449(1-2):95-102
1	J:333189 Nambiar SM, Lee J, Yanum JA, Garcia V, Jiang H, Dai G, Maternal hepatocytes heterogeneously and dynamically exhibit developmental phenotypes partially via yes-associated protein 1 during pregnancy. Am J Physiol Gastrointest Liver Physiol. 2023 Jan 1;324(1):G38-G50
1	J:219210 Nikolaou KC, Moulos P, Chalepakis G, Hatzis P, Oda H, Reinberg D, Talianidis I, Spontaneous development of hepatocellular carcinoma with cancer stem cell properties in PR-SET7-deficient livers. EMBO J. 2015 Feb 12;34(4):430-47
1*	J:316295 Ochiai W, Hirose A, Kawamura T, Komachi K, Yamamoto Y, Kitaoka S, Hatogai J, Kusunoki Y, Kon R, Ikarashi N, Sugiyama K, Role of the Drug-Metabolizing Enzyme CYP during Mouse Liver Development. Biol Pharm Bull. 2016;39(12):2015-2021
1	J:146853 Oikawa T, Kamiya A, Kakinuma S, Zeniya M, Nishinakamura R, Tajiri H, Nakauchi H, Sall4 regulates cell fate decision in fetal hepatic stem/progenitor cells. Gastroenterology. 2009 Mar;136(3):1000-11
1	J:315740 Prevot PP, Augereau C, Simion A, Van den Steen G, Dauguet N, Lemaigre FP, Jacquemin P, Let-7b and miR-495 stimulate differentiation and prevent metaplasia of pancreatic acinar cells by repressing HNF6. Gastroenterology. 2013 Sep;145(3):668-78.e3
1	J:180846 Saito K, Ogawa A, Toyofuku K, Hosoi Y, Soma M, Iha M, Kasuga K, Kojima I, Kobayashi M, Relationships between homeoprotein EGAM1C and the expression of the placental prolactin gene family in mouse placentae and trophoblast stem cells. Reproduction. 2011 Feb;141(2):259-68
1*	J:187541 Schievenbusch S, Sauer E, Curth HM, Schulte S, Demir M, Toex U, Goeser T, Nierhoff D, Neighbor of punc e 11: expression pattern of the new hepatic stem/progenitor cell marker during murine liver development. Stem Cells Dev. 2012 Sep 20;21(14):2656-66
1	J:65026 Scohy S, Gabant P, Szpirer C, Szpirer J, Identification of an enhancer and an alternative promoter in the first intron of the alpha-fetoprotein gene. Nucleic Acids Res. 2000 Oct 1;28(19):3743-51
1*	J:272586 Suzuki T, Kikuguchi C, Nishijima S, Nagashima T, Takahashi A, Okada M, Yamamoto T, Postnatal liver functional maturation requires Cnot complex-mediated decay of mRNAs encoding cell cycle and immature liver genes. Development. 2019 Feb 15;146(4):dev168146
1	J:138818 Tatarakis A, Margaritis T, Martinez-Jimenez CP, Kouskouti A, Mohan WS 2nd, Haroniti A, Kafetzopoulos D, Tora L, Talianidis I, Dominant and redundant functions of TFIID involved in the regulation of hepatic genes. Mol Cell. 2008 Aug 22;31(4):531-43
1*	J:137798 Tomizawa M, Toyama Y, Ito C, Toshimori K, Iwase K, Takiguchi M, Saisho H, Yokosuka O, Hepatoblast-like cells enriched from mouse embryonic stem cells in medium without glucose, pyruvate, arginine, and tyrosine. Cell Tissue Res. 2008 Jul;333(1):17-27
1*	J:73291 Torres-Padilla ME, Fougere-Deschatrette C, Weiss MC, Expression of HNF4alpha isoforms in mouse liver development is regulated by sequential promoter usage and constitutive 3' end splicing. Mech Dev. 2001 Dec;109(2):183-93
1	J:278909 Weng SY, Yang CY, Li CC, Sun TP, Tung SY, Yen JJ, Tsai TF, Chen CM, Chen SH, Hsiao M, Huang PH, Yang-Yen HF, Synergism between p53 and Mcl-1 in protecting from hepatic injury, fibrosis and cancer. J Hepatol. 2011 Apr;54(4):685-94
1*	J:140053 Xie Z, Zhang H, Tsai W, Zhang Y, Du Y, Zhong J, Szpirer C, Zhu M, Cao X, Barton MC, Grusby MJ, Zhang WJ, Zinc finger protein ZBTB20 is a key repressor of alpha-fetoprotein gene transcription in liver. Proc Natl Acad Sci U S A. 2008 Aug 5;105(31):10859-64
1	J:247907 Yao J, Guihard PJ, Wu X, Blazquez-Medela AM, Spencer MJ, Jumabay M, Tontonoz P, Fogelman AM, Bostrom KI, Yao Y, Vascular endothelium plays a key role in directing pulmonary epithelial cell differentiation. J Cell Biol. 2017 Oct 02;216(10):3369-3385