Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Kit  KIT proto-oncogene receptor tyrosine kinase   (Synonyms: belly-spot, CD117, c-KIT, Dominant white spotting, Gsfsco1, Gsfsco5, Gsfsow3, SCO1, SCO5, SOW3, Steel Factor Receptor, Tr-kit)
Results	Reference
1	J:12586 Arceci RJ, Pampfer S, Pollard JW, Role and expression of colony stimulating factor-1 and steel factor receptors and their ligands during pregnancy in the mouse. Reprod Fertil Dev. 1992;4:619-32
1*	J:109310 Ballow D, Meistrich ML, Matzuk M, Rajkovic A, Sohlh1 is essential for spermatogonial differentiation. Dev Biol. 2006 Jun 1;294(1):161-7
1	J:116633 Beckett EA, Ro S, Bayguinov Y, Sanders KM, Ward SM, Kit signaling is essential for development and maintenance of interstitial cells of Cajal and electrical rhythmicity in the embryonic gastrointestinal tract. Dev Dyn. 2007 Jan;236(1):60-72
1*	J:86230 Cusella De Angelis MG, Balconi G, Bernasconi S, Zanetta L, Boratto R, Galli D, Dejana E, Cossu G, Skeletal myogenic progenitors in the endothelium of lung and yolk sac. Exp Cell Res. 2003 Nov 1;290(2):207-16
1	J:342617 Dali O, D'Cruz S, Legoff L, Diba Lahmidi M, Heitz C, Merret PE, Kernanec PY, Pakdel F, Smagulova F, Transgenerational epigenetic effects imposed by neonicotinoid thiacloprid exposure. Life Sci Alliance. 2024 Feb;7(2)
1	J:265597 Gao X, Ma W, Nie J, Zhang C, Zhang J, Yao G, Han J, Xu J, Hu B, Du Y, Shi Q, Yang Z, Huang X, Zhang Y, A G-quadruplex DNA structure resolvase, RHAU, is essential for spermatogonia differentiation. Cell Death Dis. 2015 Jan 22;6:e1610
1*	J:306806 Hauser BR, Aure MH, Kelly MC, Hoffman MP, Chibly AM, Generation of a Single-Cell RNAseq Atlas of Murine Salivary Gland Development. iScience. 2020 Dec 18;23(12):101838
1	J:344559 Hughes CHK, Smith OE, Meinsohn MC, Brunelle M, Gevry N, Murphy BD, Steroidogenic factor 1 (SF-1; Nr5a1) regulates the formation of the ovarian reserve. Proc Natl Acad Sci U S A. 2023 Aug 8;120(32):e2220849120
1	J:289708 Jiang X, Yin S, Fan S, Bao J, Jiao Y, Ali A, Iqbal F, Xu J, Zhang Y, Shi Q, Npat-dependent programmed Sertoli cell proliferation is indispensable for testis cord development and germ cell mitotic arrest. FASEB J. 2019 Aug;33(8):9075-9086
1	J:277950 Kang HM, Huang S, Reidy K, Han SH, Chinga F, Susztak K, Sox9-Positive Progenitor Cells Play a Key Role in Renal Tubule Epithelial Regeneration in Mice. Cell Rep. 2016 Feb 2;14(4):861-871
1	J:338829 Lee J, Kim Y, Ataliotis P, Kim HG, Kim DW, Bennett DC, Brown NA, Layman LC, Kim SH, Coordination of canonical and noncanonical Hedgehog signalling pathways mediated by WDR11 during primordial germ cell development. Sci Rep. 2023 Jul 29;13(1):12309
1*	J:95901 Li Q, Ishikawa TO, Miyoshi H, Oshima M, Taketo MM, A targeted mutation of Nkd1 impairs mouse spermatogenesis. J Biol Chem. 2005 Jan 28;280(4):2831-9
1*	J:258384 Li R, Vannitamby A, Yue SSK, Handelsman D, Hutson J, Mouse minipuberty coincides with gonocyte transformation into spermatogonial stem cells: a model for human minipuberty. Reprod Fertil Dev. 2017 Nov;29(12):2430-2436
1	J:130359 Liang H, Coles AH, Zhu Z, Zayas J, Jurecic R, Kang J, Jones SN, Noncanonical Wnt signaling promotes apoptosis in thymocyte development. J Exp Med. 2007 Dec 24;204(13):3077-84
1	J:244859 Liu W, Wang F, Xu Q, Shi J, Zhang X, Lu X, Zhao ZA, Gao Z, Ma H, Duan E, Gao F, Gao S, Yi Z, Li L, BCAS2 is involved in alternative mRNA splicing in spermatogonia and the transition to meiosis. Nat Commun. 2017 Jan 27;8:14182
1	J:334438 Lombaert IM, Abrams SR, Li L, Eswarakumar VP, Sethi AJ, Witt RL, Hoffman MP, Combined KIT and FGFR2b signaling regulates epithelial progenitor expansion during organogenesis. Stem Cell Reports. 2013 Dec;1(6):604-19
1*	J:112870 Mager J, Schultz RM, Brunk BP, Bartolomei MS, Identification of candidate maternal-effect genes through comparison of multiple microarray data sets. Mamm Genome. 2006 Sep;17(9):941-9
1	J:194288 Manosalva I, Gonzalez A, Kageyama R, Hes1 in the somatic cells of the murine ovary is necessary for oocyte survival and maturation. Dev Biol. 2013 Mar 15;375(2):140-51
1*	J:39086 Marcos MA, Morales-Alcelay S, Godin IE, Dieterlen-Lievre F, Copin SG, Gaspar ML, Antigenic phenotype and gene expression pattern of lymphohemopoietic progenitors during early mouse ontogeny. J Immunol. 1997 Mar 15;158(6):2627-37
1*	J:36245 McClanahan T, Culpepper J, Campbell D, Wagner J, Franz-Bacon K, Mattson J, Tsai S, Luh J, Guimaraes MJ, Mattei MG, Rosnet O, Birnbaum D, Hannum CH, Biochemical and genetic characterization of multiple splice variants of the Flt3 ligand. Blood. 1996 Nov 1;88(9):3371-82
1*	J:12563 McClanahan T, Dalrymple S, Barkett M, Lee F, Hematopoietic growth factor receptor genes as markers of lineage commitment during in vitro development of hematopoietic cells [see comments]. Blood. 1993 Jun 1;81(11):2903-15
1*	J:328290 Nakagawa T, Jorg DJ, Watanabe H, Mizuno S, Han S, Ikeda T, Omatsu Y, Nishimura K, Fujita M, Takahashi S, Kondoh G, Simons BD, Yoshida S, Nagasawa T, A multistate stem cell dynamics maintains homeostasis in mouse spermatogenesis. Cell Rep. 2021 Oct 19;37(3):109875
1	J:320380 Patel VN, Pineda DL, Berenstein E, Hauser BR, Choi S, Prochazkova M, Zheng C, Goldsmith CM, van Kuppevelt TH, Kulkarni A, Song Y, Linhardt RJ, Chibly AM, Hoffman MP, Loss of Hs3st3a1 or Hs3st3b1 enzymes alters heparan sulfate to reduce epithelial morphogenesis and adult salivary gland function. Matrix Biol. 2021 Sep;103-104:37-57
1	J:168860 Payne CJ, Gallagher SJ, Foreman O, Dannenberg JH, Depinho RA, Braun RE, Sin3a is required by sertoli cells to establish a niche for undifferentiated spermatogonia, germ cell tumors, and spermatid elongation. Stem Cells. 2010 Aug;28(8):1424-34
1*	J:241573 Pui HP, Saga Y, Gonocytes-to-spermatogonia transition initiates prior to birth in murine testes and it requires FGF signaling. Mech Dev. 2017 Apr;144(Pt B):125-139
1	J:92421 Rajkovic A, Pangas SA, Ballow D, Suzumori N, Matzuk MM, NOBOX deficiency disrupts early folliculogenesis and oocyte-specific gene expression. Science. 2004 Aug 20;305(5687):1157-9
1	J:325352 Sahut-Barnola I, Lefrancois-Martinez AM, Dufour D, Botto JM, Kamilaris C, Faucz FR, Stratakis CA, Val P, Martinez A, Steroidogenic Factor-1 Lineage Origin of Skin Lesions in Carney Complex Syndrome. J Invest Dermatol. 2022 May 12;
1	J:80260 Son WY, Han CT, Lee JH, Jung KY, Lee HM, Choo YK, Developmental expression patterns of alpha1H T-type Ca2+ channels during spermatogenesis and organogenesis in mice. Dev Growth Differ. 2002 Jun;44(3):181-90
1	J:288454 Sun G, Liang X, Qin K, Qin Y, Shi X, Cong P, Mo D, Liu X, Chen Y, He Z, Functional Analysis of KIT Gene Structural Mutations Causing the Porcine Dominant White Phenotype Using Genome Edited Mouse Models. Front Genet. 2020;11:138
1*	J:98774 Takayama T, Mishima T, Mori M, Jin H, Tsukamoto H, Takahashi K, Takizawa T, Kinoshita K, Suzuki M, Sato I, Matsubara S, Araki Y, Takizawa T, Sexually Dimorphic Expression of the Novel Germ Cell Antigen TEX101 During Mouse Gonad Development. Biol Reprod. 2005 Jun;72(6):1315-23
1*	J:143535 Toyoda S, Miyazaki T, Miyazaki S, Yoshimura T, Yamamoto M, Tashiro F, Yamato E, Miyazaki J, Sohlh2 affects differentiation of KIT positive oocytes and spermatogonia. Dev Biol. 2009 Jan 1;325(1):238-48
1	J:332220 Uchida A, Imaimatsu K, Suzuki H, Han X, Ushioda H, Uemura M, Imura-Kishi K, Hiramatsu R, Takase HM, Hirate Y, Ogura A, Kanai-Azuma M, Kudo A, Kanai Y, SOX17-positive rete testis epithelium is required for Sertoli valve formation and normal spermiogenesis in the male mouse. Nat Commun. 2022 Dec 21;13(1):7860
1	J:292794 Xia X, Zhou X, Quan Y, Hu Y, Xing F, Li Z, Xu B, Xu C, Zhang A, Germline deletion of Cdyl causes teratozoospermia and progressive infertility in male mice. Cell Death Dis. 2019 Mar 8;10(3):229
1*	J:18760 Yamazaki M, Tsujimura T, Morii E, Isozaki K, Onoue H, Nomura S, Kitamura Y, C-kit gene is expressed by skin mast cells in embryos but not in puppies of Wsh/Wsh mice: age-dependent abolishment of c-kit gene expression. Blood. 1994 Jun 15;83(12):3509-16
1*	J:43157 Yoder MC, Hiatt K, Dutt P, Mukherjee P, Bodine DM, Orlic D, Characterization of definitive lymphohematopoietic stem cells in the day 9 murine yolk sac. Immunity. 1997 Sep;7(3):335-44
1	J:205485 Yu C, Zhang YL, Pan WW, Li XM, Wang ZW, Ge ZJ, Zhou JJ, Cang Y, Tong C, Sun QY, Fan HY, CRL4 complex regulates mammalian oocyte survival and reprogramming by activation of TET proteins. Science. 2013 Dec 20;342(6165):1518-21