Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Igf1r  insulin-like growth factor I receptor   (Synonyms: A330103N21Rik, CD221, hyft, IGF-1R, line 186)
Results	Reference
1	J:338901 Boogerd CJ, Perini I, Kyriakopoulou E, Han SJ, La P, van der Swaan B, Berkhout JB, Versteeg D, Monshouwer-Kloots J, van Rooij E, Cardiomyocyte proliferation is suppressed by ARID1A-mediated YAP inhibition during cardiac maturation. Nat Commun. 2023 Aug 5;14(1):4716
1*	J:98507 Caton J, Bringas P Jr, Zeichner-David M, IGFs increase enamel formation by inducing expression of enamel mineralizing specific genes. Arch Oral Biol. 2005 Feb;50(2):123-9
1	J:314222 Celaya AM, Rodriguez-de la Rosa L, Bermudez-Munoz JM, Zubeldia JM, Roma-Mateo C, Avendano C, Pallardo FV, Varela-Nieto I, IGF-1 Haploinsufficiency Causes Age-Related Chronic Cochlear Inflammation and Increases Noise-Induced Hearing Loss. Cells. 2021 Jul 3;10(7)
1	J:224562 Chen Q, Sinha K, Deng JM, Yasuda H, Krahe R, Behringer RR, de Crombrugghe B, Mesenchymal Deletion of Histone Demethylase NO66 in Mice Promotes Bone Formation. J Bone Miner Res. 2015 Sep;30(9):1608-17
1	J:223357 Chen Q, Zhang L, de Crombrugghe B, Krahe R, Mesenchyme-specific overexpression of nucleolar protein 66 in mice inhibits skeletal growth and bone formation. FASEB J. 2015 Jun;29(6):2555-65
1*	J:225886 de Iriarte Rodriguez R, Pulido S, Rodriguez-de la Rosa L, Magarinos M, Varela-Nieto I, Age-regulated function of autophagy in the mouse inner ear. Hear Res. 2015 Dec;330(Pt A):39-50
1*	J:46439 Freeman TC, Dixon AK, Campbell EA, Tait TM, Richardson PJ, Rice KM, Maslen GL, Metcalfe AD, Streuli CH, Bentley DR, Expression Mapping of Mouse Genes. MGI Direct Data Submission. 1998;
1	J:330322 Gao F, Li C, Smith SM, Peinado N, Kohbodi G, Tran E, Loh YE, Li W, Borok Z, Minoo P, Decoding the IGF1 signaling gene regulatory network behind alveologenesis from a mouse model of bronchopulmonary dysplasia. Elife. 2022 Oct 10;11:e77522
1	J:190464 Keniry A, Oxley D, Monnier P, Kyba M, Dandolo L, Smits G, Reik W, The H19 lincRNA is a developmental reservoir of miR-675 that suppresses growth and Igf1r. Nat Cell Biol. 2012 Jul;14(7):659-65
1	J:326523 Kheirollahi V, Khadim A, Kiliaris G, Korfei M, Barroso MM, Alexopoulos I, Vazquez-Armendariz AI, Wygrecka M, Ruppert C, Guenther A, Seeger W, Herold S, El Agha E, Transcriptional Profiling of Insulin-like Growth Factor Signaling Components in Embryonic Lung Development and Idiopathic Pulmonary Fibrosis. Cells. 2022 Jun 20;11(12)
1	J:327072 Kim WK, Olson AW, Mi J, Wang J, Lee DH, Le V, Hiroto A, Aldahl J, Nenninger CH, Buckley AJ, Cardiff R, You S, Sun Z, Aberrant androgen action in prostatic progenitor cells induces oncogenesis and tumor development through IGF1 and Wnt axes. Nat Commun. 2022 Jul 28;13(1):4364
1	J:241923 Lopez IP, Pineiro-Hermida S, Pais RS, Torrens R, Hoeflich A, Pichel JG, Involvement of Igf1r in Bronchiolar Epithelial Regeneration: Role during Repair Kinetics after Selective Club Cell Ablation. PLoS One. 2016;11(11):e0166388
1	J:333829 Lopez-Tello J, Sferruzzi-Perri AN, Characterization of placental endocrine function and fetal brain development in a mouse model of small for gestational age. Front Endocrinol (Lausanne). 2023;14:1116770
1	J:239654 Marongiu M, Marcia L, Pelosi E, Lovicu M, Deiana M, Zhang Y, Puddu A, Loi A, Uda M, Forabosco A, Schlessinger D, Crisponi L, FOXL2 modulates cartilage, skeletal development and IGF1-dependent growth in mice. BMC Dev Biol. 2015 Jul 02;15:27
1	J:92077 Mazerbourg S, Bouley DM, Sudo S, Klein CA, Zhang JV, Kawamura K, Goodrich LV, Rayburn H, Tessier-Lavigne M, Hsueh AJ, Leucine-rich repeat-containing, g protein-coupled receptor 4 null mice exhibit intrauterine growth retardation associated with embryonic and perinatal lethality. Mol Endocrinol. 2004 Sep;18(9):2241-54
1	J:86618 Nef S, Verma-Kurvari S, Merenmies J, Vassalli JD, Efstratiadis A, Accili D, Parada LF, Testis determination requires insulin receptor family function in mice. Nature. 2003 Nov 20;426(6964):291-5
1	J:178908 Okano T, Xuan S, Kelley MW, Insulin-like growth factor signaling regulates the timing of sensory cell differentiation in the mouse cochlea. J Neurosci. 2011 Dec 7;31(49):18104-18
1*	J:35225 Rappolee DA, Sturm KS, Behrendtsen O, Schultz GA, Pedersen RA, Werb Z, Insulin-like growth factor II acts through an endogenous growth pathway regulated by imprinting in early mouse embryos. Genes Dev. 1992 Jun;6(6):939-52
1	J:223633 Sanchez-Calderon H, Rodriguez-de la Rosa L, Milo M, Pichel JG, Holley M, Varela-Nieto I, RNA microarray analysis in prenatal mouse cochlea reveals novel IGF-I target genes: implication of MEF2 and FOXM1 transcription factors. PLoS One. 2010;5(1):e8699
1*	J:171727 Schlesinger J, Schueler M, Grunert M, Fischer JJ, Zhang Q, Krueger T, Lange M, Tonjes M, Dunkel I, Sperling SR, The cardiac transcription network modulated by Gata4, Mef2a, Nkx2.5, Srf, histone modifications, and microRNAs. PLoS Genet. 2011 Feb;7(2):e1001313
1	J:241448 Shin JY, Mendez-Lopez I, Hong M, Wang Y, Tanji K, Wu W, Shugol L, Krauss RS, Dauer WT, Worman HJ, Lamina-associated polypeptide 1 is dispensable for embryonic myogenesis but required for postnatal skeletal muscle growth. Hum Mol Genet. 2017 Jan 01;26(1):65-78
1*	J:10840 Telford NA, Hogan A, Franz CR, Schultz GA, Expression of genes for insulin and insulin-like growth factors and receptors in early postimplantation mouse embryos and embryonal carcinoma cells. Mol Reprod Dev. 1990 Oct;27(2):81-92
1*	J:197015 Thompson PJ, Norton KA, Niri FH, Dawe CE, McDermid HE, CECR2 is involved in spermatogenesis and forms a complex with SNF2H in the testis. J Mol Biol. 2012 Feb 3;415(5):793-806
1	J:156412 Tunster SJ, Tycko B, John RM, The imprinted Phlda2 gene regulates extraembryonic energy stores. Mol Cell Biol. 2010 Jan;30(1):295-306
1	J:121631 Xie L, Chen H, Overbeek PA, Reneker LW, Elevated insulin signaling disrupts the growth and differentiation pattern of the mouse lens. Mol Vis. 2007;13:397-407
1	J:74920 Yamane A, Mayo ML, Shuler C, The expression of insulin-like growth factor-I, II and their cognate receptor 1 and 2 during mouse tongue embryonic and neonatal development. Zoolog Sci. 2000;17:935-945