Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Hsd3b1  hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1   (Synonyms: D3Ertd383e)
Results	Reference
1*	J:39896 Abbaszade IG, Arensburg J, Park CH, Kasa-Vubu JZ, Orly J, Payne AH, Isolation of a new mouse 3beta-hydroxysteroid dehydrogenase isoform, 3beta-HSD VI, expressed during early pregnancy. Endocrinology. 1997 Apr;138(4):1392-9
1	J:331266 Abou Nader N, Menard A, Levasseur A, St-Jean G, Boerboom D, Zamberlam G, Boyer A, Targeted Disruption of Lats1 and Lats2 in Mice Impairs Testis Development and Alters Somatic Cell Fate. Int J Mol Sci. 2022 Nov 5;23(21)
1	J:54396 Baker PJ, Sha JA, McBride MW, Peng L, Payne AH, O'Shaughnessy PJ, Expression of 3beta-hydroxysteroid dehydrogenase type I and type VI isoforms in the mouse testis during development. Eur J Biochem. 1999 Mar;260(3):911-7
1	J:308912 Bergeron F, Boulende Sab A, Bouchard MF, Taniguchi H, Souchkova O, Brousseau C, Tremblay JJ, Pilon N, Viger RS, Phosphorylation of GATA4 serine 105 but not serine 261 is required for testosterone production in the male mouse. Andrology. 2019 May;7(3):357-372
1*	J:210262 Boucher E, Provost PR, Tremblay Y, Ontogeny of adrenal-like glucocorticoid synthesis pathway and of 20alpha-hydroxysteroid dehydrogenase in the mouse lung. BMC Res Notes. 2014;7:119
1	J:189958 Buaas FW, Gardiner JR, Clayton S, Val P, Swain A, In vivo evidence for the crucial role of SF1 in steroid-producing cells of the testis, ovary and adrenal gland. Development. 2012 Dec;139(24):4561-70
1	J:223361 Kaftanovskaya EM, Lopez C, Ferguson L, Myhr C, Agoulnik AI, Genetic ablation of androgen receptor signaling in fetal Leydig cell lineage affects Leydig cell functions in adult testis. FASEB J. 2015 Jun;29(6):2327-37
1	J:138575 Kim AC, Reuter AL, Zubair M, Else T, Serecky K, Bingham NC, Lavery GG, Parker KL, Hammer GD, Targeted disruption of beta-catenin in Sf1-expressing cells impairs development and maintenance of the adrenal cortex. Development. 2008 Aug;135(15):2593-602
1	J:222787 Liu C, Peng J, Matzuk MM, Yao HH, Lineage specification of ovarian theca cells requires multicellular interactions via oocyte and granulosa cells. Nat Commun. 2015;6:6934
1	J:237537 Liu C, Rodriguez K, Yao HH, Mapping lineage progression of somatic progenitor cells in the mouse fetal testis. Development. 2016 Oct 15;143(20):3700-3710
1	J:333829 Lopez-Tello J, Sferruzzi-Perri AN, Characterization of placental endocrine function and fetal brain development in a mouse model of small for gestational age. Front Endocrinol (Lausanne). 2023;14:1116770
1	J:306136 Manti M, Pui HP, Edstrom S, Risal S, Lu H, Lindgren E, Ohlsson C, Jerlhag E, Benrick A, Deng Q, Stener-Victorin E, Excess of ovarian nerve growth factor impairs embryonic development and causes reproductive and metabolic dysfunction in adult female mice. FASEB J. 2020 Nov;34(11):14440-14457
1	J:269227 Mathieu M, Drelon C, Rodriguez S, Tabbal H, Septier A, Damon-Soubeyrand C, Dumontet T, Berthon A, Sahut-Barnola I, Djari C, Batisse-Lignier M, Pointud JC, Richard D, Kerdivel G, Calmejane MA, Boeva V, Tauveron I, Lefrancois-Martinez AM, Martinez A, Val P, Steroidogenic differentiation and PKA signaling are programmed by histone methyltransferase EZH2 in the adrenal cortex. Proc Natl Acad Sci U S A. 2018 Dec 26;115(52):E12265-E12274
1	J:278935 Novoselova TV, Hussain M, King PJ, Guasti L, Metherell LA, Charalambous M, Clark AJL, Chan LF, MRAP deficiency impairs adrenal progenitor cell differentiation and gland zonation. FASEB J. 2018 Jun 7;:fj201701274RR
1*	J:46691 O'Shaughnessy PJ, Baker P, Sohnius U, Haavisto AM, Charlton HM, Huhtaniemi I, Fetal development of Leydig cell activity in the mouse is independent of pituitary gonadotroph function. Endocrinology. 1998 Mar;139(3):1141-6
1	J:222045 Padua MB, Jiang T, Morse DA, Fox SC, Hatch HM, Tevosian SG, Combined loss of the GATA4 and GATA6 transcription factors in male mice disrupts testicular development and confers adrenal-like function in the testes. Endocrinology. 2015 May;156(5):1873-86
1*	J:31483 Park CH, Abbaszade IG, Payne AH, Expression of multiple forms of 3 beta-hydroxysteroid dehydrogenase in the mouse liver during fetal and postnatal development. Mol Cell Endocrinol. 1996 Feb 5;116(2):157-64
1	J:205146 Praktiknjo SD, Llamas B, Scott-Boyer MP, Picard S, Robert F, Langlais D, Haibe-Kains B, Faubert D, Silversides DW, Deschepper CF, Novel effects of chromosome Y on cardiac regulation, chromatin remodeling, and neonatal programming in male mice. Endocrinology. 2013 Dec;154(12):4746-56
1	J:327192 Rossitto M, Dejardin S, Rands CM, Le Gras S, Migale R, Rafiee MR, Neirijnck Y, Pruvost A, Nguyen AL, Bossis G, Cammas F, Le Gallic L, Wilhelm D, Lovell-Badge R, Boizet-Bonhoure B, Nef S, Poulat F, TRIM28-dependent SUMOylation protects the adult ovary from activation of the testicular pathway. Nat Commun. 2022 Jul 29;13(1):4412
1	J:308864 Rotgers E, Nicol B, Rodriguez K, Rattan S, Flaws JA, Yao HH, Constitutive expression of Steroidogenic factor-1 (NR5A1) disrupts ovarian functions, fertility, and metabolic homeostasis in female mice. FASEB J. 2021 Aug;35(8):e21770
1*	J:115979 Schulte DM, Shapiro I, Reincke M, Beuschlein F, Expression and spatio-temporal distribution of differentiation and proliferation markers during mouse adrenal development. Gene Expr Patterns. 2007 Jan;7(1-2):72-81
1	J:222173 Solano ME, Kowal MK, O'Rourke GE, Horst AK, Modest K, Plosch T, Barikbin R, Remus CC, Berger RG, Jago C, Ho H, Sass G, Parker VJ, Lydon JP, DeMayo FJ, Hecher K, Karimi K, Arck PC, Progesterone and HMOX-1 promote fetal growth by CD8+ T cell modulation. J Clin Invest. 2015 Apr;125(4):1726-38
1	J:133934 Tomizuka K, Horikoshi K, Kitada R, Sugawara Y, Iba Y, Kojima A, Yoshitome A, Yamawaki K, Amagai M, Inoue A, Oshima T, Kakitani M, R-spondin1 plays an essential role in ovarian development through positively regulating Wnt-4 signaling. Hum Mol Genet. 2008 May 1;17(9):1278-91
1	J:286995 Wang YQ, Cheng JM, Wen Q, Tang JX, Li J, Chen SR, Liu YX, An exploration of the role of Sertoli cells on fetal testis development using cell ablation strategy. Mol Reprod Dev. 2020 Feb;87(2):223-230
1	J:340792 Whiley PAF, Luu MCM, O'Donnell L, Handelsman DJ, Loveland KL, Testis exposure to unopposed/elevated activin A in utero affects somatic and germ cells and alters steroid levels mimicking phthalate exposure. Front Endocrinol (Lausanne). 2023;14:1234712