Assay
Age
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In situ reporter (knock in)
Postnatal
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Efnb2 ephrin B2 (Synonyms: ELF-2, Epl5, Eplg5, Htk-L, Lerk5, LERK-5, NLERK-1) | |
Results | Reference |
1 | J:240790 Aghajanian H, Cho YK, Manderfield LJ, Herling MR, Gupta M, Ho VC, Li L, Degenhardt K, Aharonov A, Tzahor E, Epstein JA, Coronary vasculature patterning requires a novel endothelial ErbB2 holoreceptor. Nat Commun. 2016 Jun 30;7:12038 |
1 | J:221761 Bennett KM, Afanador MD, Lal CV, Xu H, Persad E, Legan SK, Chenaux G, Dellinger M, Savani RC, Dravis C, Henkemeyer M, Schwarz MA, Ephrin-B2 reverse signaling increases alpha5beta1 integrin-mediated fibronectin deposition and reduces distal lung compliance. Am J Respir Cell Mol Biol. 2013 Oct;49(4):680-7 |
1* | J:191212 Benson MD, Opperman LA, Westerlund J, Fernandez CR, San Miguel S, Henkemeyer M, Chenaux G, Ephrin-B stimulation of calvarial bone formation. Dev Dyn. 2012 Dec;241(12):1901-10 |
1 | J:267128 Chalothorn D, Faber JE, Formation and maturation of the native cerebral collateral circulation. J Mol Cell Cardiol. 2010 Aug;49(2):251-9 |
1 | J:91492 Cowan CA, Yokoyama N, Saxena A, Chumley MJ, Silvany RE, Baker LA, Srivastava D, Henkemeyer M, Ephrin-B2 reverse signaling is required for axon pathfinding and cardiac valve formation but not early vascular development. Dev Biol. 2004 Jul 15;271(2):263-71 |
1 | J:222780 Defourny J, Mateo Sanchez S, Schoonaert L, Robberecht W, Davy A, Nguyen L, Malgrange B, Cochlear supporting cell transdifferentiation and integration into hair cell layers by inhibition of ephrin-B2 signalling. Nat Commun. 2015;6:7017 |
1 | J:116671 Dravis C, Wu T, Chumley MJ, Yokoyama N, Wei S, Wu DK, Marcus DC, Henkemeyer M, EphB2 and ephrin-B2 regulate the ionic homeostasis of vestibular endolymph. Hear Res. 2007 Jan;223(1-2):93-104 |
1 | J:157054 Egawa G, Osawa M, Uemura A, Miyachi Y, Nishikawa S, Transient expression of ephrin b2 in perinatal skin is required for maintenance of keratinocyte homeostasis. J Invest Dermatol. 2009 Oct;129(10):2386-95 |
1 | J:115909 Foo SS, Turner CJ, Adams S, Compagni A, Aubyn D, Kogata N, Lindblom P, Shani M, Zicha D, Adams RH, Ephrin-B2 controls cell motility and adhesion during blood-vessel-wall assembly. Cell. 2006 Jan 13;124(1):161-73 |
1 | J:67371 Gale NW, Baluk P, Pan L, Kwan M, Holash J, DeChiara TM, McDonald DM, Yancopoulos GD, Ephrin-B2 selectively marks arterial vessels and neovascularization sites in the adult, with expression in both endothelial and smooth-muscle cells. Dev Biol. 2001 Feb 15;230(2):151-60 |
1* | J:198558 Li W, Mukouyama YS, Tissue-specific venous expression of the EPH family receptor EphB1 in the skin vasculature. Dev Dyn. 2013 Aug;242(8):976-88 |
1 | J:312382 Lyons O, Walker J, Seet C, Ikram M, Kuchta A, Arnold A, Hernandez-Vasquez M, Frye M, Vizcay-Barrena G, Fleck RA, Patel AS, Padayachee S, Mortimer P, Jeffery S, Berland S, Mansour S, Ostergaard P, Makinen T, Modarai B, Saha P, Smith A, Mutations in EPHB4 cause human venous valve aplasia. JCI Insight. 2021 Sep 22;6(18):e140952 |
1 | J:95885 Makinen T, Adams RH, Bailey J, Lu Q, Ziemiecki A, Alitalo K, Klein R, Wilkinson GA, PDZ interaction site in ephrinB2 is required for the remodeling of lymphatic vasculature. Genes Dev. 2005 Feb 1;19(3):397-410 |
1* | J:86844 Takahashi T, Takahashi K, Gerety S, Wang H, Anderson DJ, Daniel TO, Temporally compartmentalized expression of ephrin-B2 during renal glomerular development. J Am Soc Nephrol. 2001 Dec;12(12):2673-82 |
1 | J:176056 Thakar S, Chenaux G, Henkemeyer M, Critical roles for EphB and ephrin-B bidirectional signalling in retinocollicular mapping. Nat Commun. 2011;2:431 |
1 | J:139011 Wilkinson GA, Schittny JC, Reinhardt DP, Klein R, Role for ephrinB2 in postnatal lung alveolar development and elastic matrix integrity. Dev Dyn. 2008 Aug;237(8):2220-34 |
1 | J:202407 Xiao Y, Woo WM, Nagao K, Li W, Terunuma A, Mukouyama YS, Oro AE, Vogel JC, Brownell I, Perivascular hair follicle stem cells associate with a venule annulus. J Invest Dermatol. 2013 Oct;133(10):2324-31 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/14/2024 MGI 6.23 |
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