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Gene Expression Literature Summary
Assay
Age
In situ RNA (section)
Postnatal

17 matching records from 17 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Cxcr4  C-X-C motif chemokine receptor 4   (Synonyms: b2b220Clo, CD184, Cmkar4, fusin, PB-CKR, Sdf1r)
Results  Reference
1J:79852 Bagri A, Gurney T, He X, Zou YR, Littman DR, Tessier-Lavigne M, Pleasure SJ, The chemokine SDF1 regulates migration of dentate granule cells. Development. 2002 Sep;129(18):4249-60
1J:196059 Hodge RD, Garcia AJ 3rd, Elsen GE, Nelson BR, Mussar KE, Reiner SL, Ramirez JM, Hevner RF, Tbr2 expression in Cajal-Retzius cells and intermediate neuronal progenitors is required for morphogenesis of the dentate gyrus. J Neurosci. 2013 Feb 27;33(9):4165-80
1J:108714 Holt JE, Jackson A, Roman SD, Aitken RJ, Koopman P, McLaughlin EA, CXCR4/SDF1 interaction inhibits the primordial to primary follicle transition in the neonatal mouse ovary. Dev Biol. 2006 May 15;293(2):449-60
1*J:199186 Juuri E, Saito K, Lefebvre S, Michon F, Establishment of crown-root domain borders in mouse incisor. Gene Expr Patterns. 2013 Oct;13(7):255-64
1*J:81783 Lu M, Grove EA, Miller RJ, Abnormal development of the hippocampal dentate gyrus in mice lacking the CXCR4 chemokine receptor. Proc Natl Acad Sci U S A. 2002 May 14;99(10):7090-5
1J:68850 Lu Q, Sun EE, Klein RS, Flanagan JG, Ephrin-B reverse signaling is mediated by a novel PDZ-RGS protein and selectively inhibits G protein-coupled chemoattraction. Cell. 2001 Apr 6;105(1):69-79
1*J:162220 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T, BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
1J:199453 Mithal DS, Ren D, Miller RJ, CXCR4 signaling regulates radial glial morphology and cell fate during embryonic spinal cord development. Glia. 2013 Aug;61(8):1288-305
1J:241853 Parisot J, Flore G, Bertacchi M, Studer M, COUP-TFI mitotically regulates production and migration of dentate granule cells and modulates hippocampal Cxcr4 expression. Development. 2017 Jun 01;144(11):2045-2058
1J:308868 Senf K, Karius J, Stumm R, Neuhaus EM, Chemokine signaling is required for homeostatic and injury-induced neurogenesis in the olfactory epithelium. Stem Cells. 2021 May;39(5):617-635
1*J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
1J:88781 Tissir F, Wang CE, Goffinet AM, Expression of the chemokine receptor Cxcr4 mRNA during mouse brain development. Brain Res Dev Brain Res. 2004 Mar 22;149(1):63-71
1*J:272319 Tiveron MC, Boutin C, Daou P, Moepps B, Cremer H, Expression and function of CXCR7 in the mouse forebrain. J Neuroimmunol. 2010;224(1-2):72-9
1J:229448 Tsai HH, Niu J, Munji R, Davalos D, Chang J, Zhang H, Tien AC, Kuo CJ, Chan JR, Daneman R, Fancy SP, Oligodendrocyte precursors migrate along vasculature in the developing nervous system. Science. 2016 Jan 22;351(6271):379-84
1J:197621 Ueno M, Fujita Y, Tanaka T, Nakamura Y, Kikuta J, Ishii M, Yamashita T, Layer V cortical neurons require microglial support for survival during postnatal development. Nat Neurosci. 2013 May;16(5):543-51
1J:327277 Venkataramanappa S, Saaber F, Abe P, Schutz D, Kumar PA, Stumm R, Cxcr4 and Ackr3 regulate allocation of caudal ganglionic eminence-derived interneurons to superficial cortical layers. Cell Rep. 2022 Aug 2;40(5):111157
1J:312813 Yokohama-Tamaki T, Otsu K, Harada H, Shibata S, Obara N, Irie K, Taniguchi A, Nagasawa T, Aoki K, Caliari SR, Weisgerber DW, Harley BA, CXCR4/CXCL12 signaling impacts enamel progenitor cell proliferation and motility in the dental stem cell niche. Cell Tissue Res. 2015 Dec;362(3):633-42

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory