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Gene Expression Literature Summary
Assay
Age
In situ RNA (section)
Postnatal

15 matching records from 15 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Pdgfa  platelet derived growth factor, alpha  
Results  Reference
1*J:29762 Bidwell MC, Eitzman BA, Walmer DK, McLachlan JA, Gray KD, Analysis of messenger ribonucleic acid and protein for the ligands and receptors of the platelet-derived growth factor signaling pathway in the placenta, extraembryonic membranes, and uterus during the latter half of murine gestation. Endocrinology. 1995 Nov;136(11):5189-201
1J:33629 Bostrom H, Willetts K, Pekny M, Leveen P, Lindahl P, Hedstrand H, Pekna M, Hellstrom M, Gebre-Medhin S, Schalling M, Nilsson M, Kurland S, Tornell J, Heath JK, Betsholtz C, PDGF-A signaling is a critical event in lung alveolar myofibroblast development and alveogenesis. Cell. 1996 Jun 14;85(6):863-73
1J:139978 Dakubo GD, Beug ST, Mazerolle CJ, Thurig S, Wang Y, Wallace VA, Control of glial precursor cell development in the mouse optic nerve by sonic hedgehog from retinal ganglion cells. Brain Res. 2008 Sep 4;1228:27-42
1J:131554 Kang J, Gu Y, Li P, Johnson BL, Sucov HM, Thomas PS, PDGF-A as an epicardial mitogen during heart development. Dev Dyn. 2008 Mar;237(3):692-701
1J:63212 Karlsson L, Lindahl P, Heath JK, Betsholtz C, Abnormal gastrointestinal development in PDGF-A and PDGFR-(alpha) deficient mice implicates a novel mesenchymal structure with putative instructive properties in villus morphogenesis. Development. 2000 Aug;127(16):3457-66
1J:347128 Kumar N, Prakash PG, Wentland C, Kurian SM, Jethva G, Brinkmann V, Mollenkopf HJ, Krammer T, Toussaint C, Saliba AE, Biebl M, Jurgensen C, Wiedenmann B, Meyer TF, Gurumurthy RK, Chumduri C, Decoding spatiotemporal transcriptional dynamics and epithelial fibroblast crosstalk during gastroesophageal junction development through single cell analysis. Nat Commun. 2024 Apr 9;15(1):3064
1*J:3676 Palmieri SL, Payne J, Stiles CD, Biggers JD, Mercola M, Expression of mouse PDGF-A and PDGF alpha-receptor genes during pre- and post-implantation development: evidence for a developmental shift from an autocrine to a paracrine mode of action. Mech Dev. 1992 Dec;39(3):181-91
1J:37334 Reneker LW, Overbeek PA, Lens-specific expression of PDGF-A alters lens growth and development. Dev Biol. 1996 Dec 15;180(2):554-65
1J:49721 Seifert RA, Alpers CE, Bowen-Pope DF, Expression of platelet-derived growth factor and its receptors in the developing and adult mouse kidney. Kidney Int. 1998 Sep;54(3):731-46
1*J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
1J:197621 Ueno M, Fujita Y, Tanaka T, Nakamura Y, Kikuta J, Ishii M, Yamashita T, Layer V cortical neurons require microglial support for survival during postnatal development. Nat Neurosci. 2013 May;16(5):543-51
1J:84053 Wang T, Tamakoshi T, Uezato T, Shu F, Kanzaki-Kato N, Fu Y, Koseki H, Yoshida N, Sugiyama T, Miura N, Forkhead transcription factor Foxf2 (LUN)-deficient mice exhibit abnormal development of secondary palate. Dev Biol. 2003 Jul 1;259(1):83-94
1J:95139 Xu X, Bringas P Jr, Soriano P, Chai Y, PDGFR-alpha signaling is critical for tooth cusp and palate morphogenesis. Dev Dyn. 2005 Jan;232(1):75-84
1*J:193306 Yeh HJ, Ruit KG, Wang YX, Parks WC, Snider WD, Deuel TF, PDGF A-chain gene is expressed by mammalian neurons during development and in maturity. Cell. 1991 Jan 11;64(1):209-16
1J:303269 Zepp JA, Morley MP, Loebel C, Kremp MM, Chaudhry FN, Basil MC, Leach JP, Liberti DC, Niethamer TK, Ying Y, Jayachandran S, Babu A, Zhou S, Frank DB, Burdick JA, Morrisey EE, Genomic, epigenomic, and biophysical cues controlling the emergence of the lung alveolus. Science. 2021 Mar 12;371(6534)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory