Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Nefh  neurofilament, heavy polypeptide   (Synonyms: mKIAA0845, NEFH, NF200, NF-H)
Results	Reference
1	J:82462 Agerman K, Hjerling-Leffler J, Blanchard MP, Scarfone E, Canlon B, Nosrat C, Ernfors P, BDNF gene replacement reveals multiple mechanisms for establishing neurotrophin specificity during sensory nervous system development. Development. 2003 Apr;130(8):1479-91
1	J:308269 Brodie-Kommit J, Clark BS, Shi Q, Shiau F, Kim DW, Langel J, Sheely C, Ruzycki PA, Fries M, Javed A, Cayouette M, Schmidt T, Badea T, Glaser T, Zhao H, Singer J, Blackshaw S, Hattar S, Atoh7-independent specification of retinal ganglion cell identity. Sci Adv. 2021 Mar;7(11)
1	J:270087 Brokhman I, Xu J, Coles BLK, Razavi R, Engert S, Lickert H, Babona-Pilipos R, Morshead CM, Sibley E, Chen C, van der Kooy D, Dual embryonic origin of the mammalian enteric nervous system. Dev Biol. 2019 Jan 15;445(2):256-270
1	J:284139 Chaimowicz C, Ruffault PL, Cheret C, Woehler A, Zampieri N, Fortin G, Garratt AN, Birchmeier C, Teashirt 1 (Tshz1) is essential for the development, survival and function of hypoglossal and phrenic motor neurons in mouse. Development. 2019 Sep 6;146(17):dev174045
1	J:265843 Chowdhury R, Laboissonniere LA, Wester AK, Muller M, Trimarchi JM, The Trim family of genes and the retina: Expression and functional characterization. PLoS One. 2018;13(9):e0202867
1	J:222780 Defourny J, Mateo Sanchez S, Schoonaert L, Robberecht W, Davy A, Nguyen L, Malgrange B, Cochlear supporting cell transdifferentiation and integration into hair cell layers by inhibition of ephrin-B2 signalling. Nat Commun. 2015;6:7017
1	J:226226 Defourny J, Poirrier AL, Lallemend F, Mateo Sanchez S, Neef J, Vanderhaeghen P, Soriano E, Peuckert C, Kullander K, Fritzsch B, Nguyen L, Moonen G, Moser T, Malgrange B, Ephrin-A5/EphA4 signalling controls specific afferent targeting to cochlear hair cells. Nat Commun. 2013;4:1438
1*	J:202451 Del Rio T, Nishitani AM, Yu WM, Goodrich LV, In vivo analysis of lrig genes reveals redundant and independent functions in the inner ear. PLoS Genet. 2013 Sep;9(9):e1003824
1	J:253766 Dvorakova M, Jahan I, Macova I, Chumak T, Bohuslavova R, Syka J, Fritzsch B, Pavlinkova G, Incomplete and delayed Sox2 deletion defines residual ear neurosensory development and maintenance. Sci Rep. 2016 Dec 5;6:38253
1	J:60774 Feng G, Laskowski MB, Feldheim DA, Wang H, Lewis R, Frisen J, Flanagan JG, Sanes JR, Roles for ephrins in positionally selective synaptogenesis between motor neurons and muscle fibers. Neuron. 2000 Feb;25(2):295-306
1	J:32903 Gan L, Xiang M, Zhou L, Wagner DS, Klein WH, Nathans J, POU domain factor Brn-3b is required for the development of a large set of retinal ganglion cells. Proc Natl Acad Sci U S A. 1996 Apr 30;93(9):3920-5
1	J:264107 Ghimire SR, Ratzan EM, Deans MR, A non-autonomous function of the core PCP protein VANGL2 directs peripheral axon turning in the developing cochlea. Development. 2018 Jun 14;145(12):dev159012
1	J:132854 Gould TW, Yonemura S, Oppenheim RW, Ohmori S, Enomoto H, The neurotrophic effects of glial cell line-derived neurotrophic factor on spinal motoneurons are restricted to fusimotor subtypes. J Neurosci. 2008 Feb 27;28(9):2131-46
1	J:254641 Groman-Lupa S, Adewumi J, Park KU, Brzezinski Iv JA, The Transcription Factor Prdm16 Marks a Single Retinal Ganglion Cell Subtype in the Mouse Retina. Invest Ophthalmol Vis Sci. 2017 Oct 1;58(12):5421-5433
1*	J:263979 Harley RJ, Murdy JP, Wang Z, Kelly MC, Ropp TF, Park SH, Maness PF, Manis PB, Coate TM, Neuronal cell adhesion molecule (NrCAM) is expressed by sensory cells in the cochlea and is necessary for proper cochlear innervation and sensory domain patterning during development. Dev Dyn. 2018 Mar 14;
1	J:160258 Holley M, Rhodes C, Kneebone A, Herde MK, Fleming M, Steel KP, Emx2 and early hair cell development in the mouse inner ear. Dev Biol. 2010 Apr 15;340(2):547-56
1	J:173361 Itoh A, Horiuchi M, Wakayama K, Xu J, Bannerman P, Pleasure D, Itoh T, ZPK/DLK, a mitogen-activated protein kinase kinase kinase, is a critical mediator of programmed cell death of motoneurons. J Neurosci. 2011 May 18;31(20):7223-8
1	J:279215 Jung JS, Zhang KD, Wang Z, McMurray M, Tkaczuk A, Ogawa Y, Hertzano R, Coate TM, Semaphorin-5B Controls Spiral Ganglion Neuron Branch Refinement during Development. J Neurosci. 2019 Aug 14;39(33):6425-6438
1*	J:299026 Kannan-Sundhari A, Abad C, Maloof ME, Ayad NG, Young JI, Liu XZ, Walz K, Bromodomain Protein BRD4 Is Essential for Hair Cell Function and Survival. Front Cell Dev Biol. 2020;8:576654
1	J:298091 Kao CS, van Bruggen R, Kim JR, Chen XXL, Chan C, Lee J, Cho WI, Zhao M, Arndt C, Maksimovic K, Khan M, Tan Q, Wilson MD, Park J, Selective neuronal degeneration in MATR3 S85C knock-in mouse model of early-stage ALS. Nat Commun. 2020 Oct 20;11(1):5304
1	J:270927 Kridsada K, Niu J, Haldipur P, Wang Z, Ding L, Li JJ, Lindgren AG, Herrera E, Thomas GM, Chizhikov VV, Millen KJ, Luo W, Roof Plate-Derived Radial Glial-like Cells Support Developmental Growth of Rapidly Adapting Mechanoreceptor Ascending Axons. Cell Rep. 2018 Jun 5;23(10):2928-2941
1	J:323375 Lee H, Lee JJ, Park NY, Dubey SK, Kim T, Ruan K, Lim SB, Park SH, Ha S, Kovlyagina I, Kim KT, Kim S, Oh Y, Kim H, Kang SU, Song MR, Lloyd TE, Maragakis NJ, Hong YB, Eoh H, Lee G, Multi-omic analysis of selectively vulnerable motor neuron subtypes implicates altered lipid metabolism in ALS. Nat Neurosci. 2021 Dec;24(12):1673-1685
1*	J:202344 Lesko MH, Driskell RR, Kretzschmar K, Goldie SJ, Watt FM, Sox2 modulates the function of two distinct cell lineages in mouse skin. Dev Biol. 2013 Oct 1;382(1):15-26
1*	J:273017 Li C, Bademci G, Subasioglu A, Diaz-Horta O, Zhu Y, Liu J, Mitchell TG, Abad C, Seyhan S, Duman D, Cengiz FB, Tokgoz-Yilmaz S, Blanton SH, Farooq A, Walz K, Zhai RG, Tekin M, Dysfunction of GRAP, encoding the GRB2-related adaptor protein, is linked to sensorineural hearing loss. Proc Natl Acad Sci U S A. 2019 Jan 22;116(4):1347-1352
1	J:321803 Niu F, Han P, Zhang J, She Y, Yang L, Yu J, Zhuang M, Tang K, Shi Y, Yang B, Liu C, Peng B, Ji SJ, The m(6)A reader YTHDF2 is a negative regulator for dendrite development and maintenance of retinal ganglion cells. Elife. 2022 Feb 18;11:e75827
1	J:134978 Pan L, Deng M, Xie X, Gan L, ISL1 and BRN3B co-regulate the differentiation of murine retinal ganglion cells. Development. 2008 Jun;135(11):1981-90
1*	J:232723 Qu C, Bian D, Li X, Xiao J, Wu C, Li Y, Jiang T, Zhou X, Qu J, Chen JG, Transient Expression of Fez Family Zinc Finger 2 Protein Regulates the Brn3b Gene in Developing Retinal Ganglion Cells. J Biol Chem. 2016 Apr 1;291(14):7661-8
1	J:216471 Sapkota D, Chintala H, Wu F, Fliesler SJ, Hu Z, Mu X, Onecut1 and Onecut2 redundantly regulate early retinal cell fates during development. Proc Natl Acad Sci U S A. 2014 Sep 30;111(39):E4086-95
1	J:272727 Shrestha BR, Chia C, Wu L, Kujawa SG, Liberman MC, Goodrich LV, Sensory Neuron Diversity in the Inner Ear Is Shaped by Activity. Cell. 2018 Aug 23;174(5):1229-1246.e17
1	J:319547 Taib S, Lamande N, Martin S, Coulpier F, Topilko P, Brunet I, Myelinating Schwann cells and Netrin-1 control intra-nervous vascularization of the developing mouse sciatic nerve. Elife. 2022 Jan 12;11:e64773
1	J:67382 Wang SW, Kim BS, Ding K, Wang H, Sun D, Johnson RL, Klein WH, Gan L, Requirement for math5 in the development of retinal ganglion cells. Genes Dev. 2001 Jan 1;15(1):24-9
1	J:220735 Wu F, Kaczynski TJ, Sethuramanujam S, Li R, Jain V, Slaughter M, Mu X, Two transcription factors, Pou4f2 and Isl1, are sufficient to specify the retinal ganglion cell fate. Proc Natl Acad Sci U S A. 2015 Mar 31;112(13):E1559-68
1	J:185531 Wu H, Lu Y, Barik A, Joseph A, Taketo MM, Xiong WC, Mei L, beta-Catenin gain of function in muscles impairs neuromuscular junction formation. Development. 2012 Jul;139(13):2392-404
1	J:207904 Yu WM, Appler JM, Kim YH, Nishitani AM, Holt JR, Goodrich LV, A Gata3-Mafb transcriptional network directs post-synaptic differentiation in synapses specialized for hearing. Elife. 2013;2:e01341