Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Notch1  notch 1   (Synonyms: 9930111A19Rik, lin-12, Mis6, Motch A, N1, Tan1)
Results	Reference
1	J:173382 Basch ML, Ohyama T, Segil N, Groves AK, Canonical Notch Signaling Is Not Necessary for Prosensory Induction in the Mouse Cochlea: Insights from a Conditional Mutant of RBPj{kappa}. J Neurosci. 2011 Jun 1;31(22):8046-58
1	J:226335 Bhattacharya S, Wheeler H, Leid M, Ganguli-Indra G, Indra AK, Transcription Factor CTIP2 Maintains Hair Follicle Stem Cell Pool and Contributes to Altered Expression of LHX2 and NFATC1. J Invest Dermatol. 2015 Nov;135(11):2593-602
1	J:184927 Bizzoca A, Corsi P, Polizzi A, Pinto MF, Xenaki D, Furley AJ, Gennarini G, F3/Contactin acts as a modulator of neurogenesis during cerebral cortex development. Dev Biol. 2012 May 1;365(1):133-51
1	J:114702 Blanpain C, Lowry WE, Pasolli HA, Fuchs E, Canonical notch signaling functions as a commitment switch in the epidermal lineage. Genes Dev. 2006 Nov 1;20(21):3022-35
1	J:185338 Boucherat O, Chakir J, Jeannotte L, The loss of Hoxa5 function promotes Notch-dependent goblet cell metaplasia in lung airways. Biol Open. 2012;q:677-691
1	J:202792 Boucherat O, Montaron S, Berube-Simard FA, Aubin J, Philippidou P, Wellik DM, Dasen JS, Jeannotte L, Partial functional redundancy between Hoxa5 and Hoxb5 paralog genes during lung morphogenesis. Am J Physiol Lung Cell Mol Physiol. 2013 Jun 15;304(12):L817-30
1	J:310741 Briot A, Jaroszewicz A, Warren CM, Lu J, Touma M, Rudat C, Hofmann JJ, Airik R, Weinmaster G, Lyons K, Wang Y, Kispert A, Pellegrini M, Iruela-Arispe ML, Repression of Sox9 by Jag1 is continuously required to suppress the default chondrogenic fate of vascular smooth muscle cells. Dev Cell. 2014 Dec 22;31(6):707-21
1	J:108618 Carson C, Murdoch B, Roskams AJ, Notch 2 and Notch 1/3 segregate to neuronal and glial lineages of the developing olfactory epithelium. Dev Dyn. 2006 Jun;235(6):1678-88
1	J:91309 Doi K, Ishida H, Nibu K, Notch expression in developing olfactory neuroepithelium. Neuroreport. 2004 Apr 29;15(6):945-7
1	J:257440 Dvoriantchikova G, Tao W, Pappas S, Gaidosh G, Tse DT, Ivanov D, Pelaez D, Molecular Profiling of the Developing Lacrimal Gland Reveals Putative Role of Notch Signaling in Branching Morphogenesis. Invest Ophthalmol Vis Sci. 2017 Feb 1;58(2):1098-1109
1	J:235678 Grisanti L, Revenkova E, Gordon RE, Iomini C, Primary cilia maintain corneal epithelial homeostasis by regulation of the Notch signaling pathway. Development. 2016 Jun 15;143(12):2160-71
1	J:104840 Grishina IB, Kim SY, Ferrara C, Makarenkova HP, Walden PD, BMP7 inhibits branching morphogenesis in the prostate gland and interferes with Notch signaling. Dev Biol. 2005 Dec 15;288(2):334-47
1	J:150873 Hartman BH, Basak O, Nelson BR, Taylor V, Bermingham-McDonogh O, Reh TA, Hes5 expression in the postnatal and adult mouse inner ear and the drug-damaged cochlea. J Assoc Res Otolaryngol. 2009 Sep;10(3):321-40
1	J:34528 Hasserjian RP, Aster JC, Davi F, Weinberg DS, Sklar J, Modulated expression of notch1 during thymocyte development. Blood. 1996 Aug 1;88(3):970-6
1	J:84012 Hayes AJ, Dowthwaite GP, Webster SV, Archer CW, The distribution of Notch receptors and their ligands during articular cartilage development. J Anat. 2003 Jun;202(6):495-502
1	J:94374 Horsford DJ, Nguyen MT, Sellar GC, Kothary R, Arnheiter H, McInnes RR, Chx10 repression of Mitf is required for the maintenance of mammalian neuroretinal identity. Development. 2005 Jan;132(1):177-87
1	J:193690 Hosaka Y, Saito T, Sugita S, Hikata T, Kobayashi H, Fukai A, Taniguchi Y, Hirata M, Akiyama H, Chung UI, Kawaguchi H, Notch signaling in chondrocytes modulates endochondral ossification and osteoarthritis development. Proc Natl Acad Sci U S A. 2013 Jan 29;110(5):1875-80
1	J:176598 Jandke A, Da Costa C, Sancho R, Nye E, Spencer-Dene B, Behrens A, The F-box protein Fbw7 is required for cerebellar development. Dev Biol. 2011 Oct 1;358(1):201-12
1	J:182895 Kaftanovskaya EM, Feng S, Huang Z, Tan Y, Barbara AM, Kaur S, Truong A, Gorlov IP, Agoulnik AI, Suppression of insulin-like3 receptor reveals the role of beta-catenin and Notch signaling in gubernaculum development. Mol Endocrinol. 2011 Jan;25(1):170-83
1	J:320186 Kalisch-Smith JI, Morris EC, Strevens MAA, Redpath AN, Klaourakis K, Szumska D, Outhwaite JE, Sun X, Vieira JM, Smart N, De Val S, Riley PR, Sparrow DB, Analysis of Placental Arteriovenous Formation Reveals New Insights Into Embryos With Congenital Heart Defects. Front Genet. 2021;12:806136
1	J:224724 Kawaguchi D, Furutachi S, Kawai H, Hozumi K, Gotoh Y, Dll1 maintains quiescence of adult neural stem cells and segregates asymmetrically during mitosis. Nat Commun. 2013;4:1880
1	J:170885 Kratsios P, Catela C, Salimova E, Huth M, Berno V, Rosenthal N, Mourkioti F, Distinct roles for cell-autonomous Notch signaling in cardiomyocytes of the embryonic and adult heart. Circ Res. 2010 Feb 19;106(3):559-72
1	J:234310 Kuo TL, Weng CC, Kuo KK, Chen CY, Wu DC, Hung WC, Cheng KH, APC haploinsufficiency coupled with p53 loss sufficiently induces mucinous cystic neoplasms and invasive pancreatic carcinoma in mice. Oncogene. 2016 Apr 28;35(17):2223-34
1	J:331419 Labbe P, Munoz Goyette V, Thorin-Trescases N, Villeneuve L, Desanlis I, Delwarde C, Shi YF, Martel C, Yu C, Alikashani A, Mamarbachi M, Lesage F, Mathieu S, Tardif JC, Mathieu P, Kmita M, Thorin E, Angiopoietin-like 2 is essential to aortic valve development in mice. Commun Biol. 2022 Nov 21;5(1):1277
1	J:228844 Leilei Y, Bing L, Yang L, Shaoxia W, Yuan X, Dongping W, Huahu Y, Shichen S, Guangzhou Z, Ruiyun P, Lin Z, Wenlong L, iRhom2 mutation leads to aberrant hair follicle differentiation in mice. PLoS One. 2014;9(12):e115114
1	J:310316 Li H, Ramachandran A, Gao Q, Ravindran S, Song Y, Evans C, George A, Expression and function of NUMB in odontogenesis. Biomed Res Int. 2013;2013:182965
1	J:86441 Lin MH, Kopan R, Long-range, nonautonomous effects of activated Notch1 on tissue homeostasis in the nail. Dev Biol. 2003 Nov 15;263(2):343-59
1*	J:197325 Lin X, Liu B, Yang X, Yue X, Diao L, Wang J, Chang J, Genetic deletion of Rnd3 results in aqueductal stenosis leading to hydrocephalus through up-regulation of Notch signaling. Proc Natl Acad Sci U S A. 2013 May 14;110(20):8236-41
1	J:224078 Liu Z, Brunskill E, Varnum-Finney B, Zhang C, Zhang A, Jay PY, Bernstein I, Morimoto M, Kopan R, The intracellular domains of Notch1 and Notch2 are functionally equivalent during development and carcinogenesis. Development. 2015 Jul 15;142(14):2452-63
1	J:233171 Mandasari M, Sawangarun W, Katsube K, Kayamori K, Yamaguchi A, Sakamoto K, A facile one-step strategy for the generation of conditional knockout mice to explore the role of Notch1 in oroesophageal tumorigenesis. Biochem Biophys Res Commun. 2016 Jan 15;469(3):761-7
1	J:26831 Mitsiadis TA, Lardelli M, Lendahl U, Thesleff I, Expression of Notch 1, 2 and 3 is regulated by epithelial-mesenchymal interactions and retinoic acid in the developing mouse tooth and associated with determination of ameloblast cell fate. J Cell Biol. 1995 Jul;130(2):407-18
1	J:324254 Muley A, Kim Uh M, Salazar-De Simone G, Swaminathan B, James JM, Murtomaki A, Youn SW, McCarron JD, Kitajewski C, Gnarra Buethe M, Riitano G, Mukouyama YS, Kitajewski J, Shawber CJ, Unique functions for Notch4 in murine embryonic lymphangiogenesis. Angiogenesis. 2022 May;25(2):205-224
1	J:143162 Murata J, Tokunaga A, Okano H, Kubo T, Mapping of notch activation during cochlear development in mice: implications for determination of prosensory domain and cell fate diversification. J Comp Neurol. 2006 Jul 20;497(3):502-18
1	J:315114 Nagosa S, Leesch F, Putin D, Bhattacharya S, Altshuler A, Serror L, Amitai-Lange A, Nasser W, Aberdam E, Rouleau M, Tattikota SG, Poy MN, Aberdam D, Shalom-Feuerstein R, microRNA-184 Induces a Commitment Switch to Epidermal Differentiation. Stem Cell Reports. 2017 Dec 12;9(6):1991-2004
1	J:309378 Naveau A, Zhang B, Meng B, Sutherland MT, Prochazkova M, Wen T, Marangoni P, Jones KB, Cox TC, Ganss B, Jheon AH, Klein OD, Isl1 Controls Patterning and Mineralization of Enamel in the Continuously Renewing Mouse Incisor. J Bone Miner Res. 2017 Nov;32(11):2219-2231
1	J:177592 Nelson BR, Ueki Y, Reardon S, Karl MO, Georgi S, Hartman BH, Lamba DA, Reh TA, Genome-wide analysis of Muller glial differentiation reveals a requirement for Notch signaling in postmitotic cells to maintain the glial fate. PLoS One. 2011;6(8):e22817
1	J:90057 Okuyama R, Nguyen BC, Talora C, Ogawa E, Tommasi di Vignano A, Lioumi M, Chiorino G, Tagami H, Woo M, Dotto GP, High commitment of embryonic keratinocytes to terminal differentiation through a Notch1-caspase 3 regulatory mechanism. Dev Cell. 2004 Apr;6(4):551-62
1	J:94517 Pan Y, Lin MH, Tian X, Cheng HT, Gridley T, Shen J, Kopan R, gamma-secretase functions through Notch signaling to maintain skin appendages but is not required for their patterning or initial morphogenesis. Dev Cell. 2004 Nov;7(5):731-43
1	J:93832 Sharma M, Fopma A, Brantley JG, Vanden Heuvel GB, Coexpression of Cux-1 and notch signaling pathway components during kidney development. Dev Dyn. 2004 Dec;231(4):828-38
1	J:127386 Shawber CJ, Funahashi Y, Francisco E, Vorontchikhina M, Kitamura Y, Stowell SA, Borisenko V, Feirt N, Podgrabinska S, Shiraishi K, Chawengsaksophak K, Rossant J, Accili D, Skobe M, Kitajewski J, Notch alters VEGF responsiveness in human and murine endothelial cells by direct regulation of VEGFR-3 expression. J Clin Invest. 2007 Nov;117(11):3369-82
1	J:132049 Shimizu T, Nakano K, Tsujigiwa H, Nagatsuka H, Watanabe T, Okafuji N, Kurihara S, Hasegawa H, Nagai N, Kawakami T, Notch signaling in mandibular condylar cartilage development. Eur J Med Res. 2007 Oct 30;12(10):515-9
1	J:79222 Taichman DB, Loomes KM, Schachtner SK, Guttentag S, Vu C, Williams P, Oakey RJ, Baldwin HS, Notch1 and Jagged1 expression by the developing pulmonary vasculature. Dev Dyn. 2002 Oct;225(2):166-75
1	J:236406 Takada Y, Fukuda A, Chiba T, Seno H, Brg1 plays an essential role in development and homeostasis of the duodenum through regulation of Notch signaling. Development. 2016 Oct 1;143(19):3532-3539
1	J:91404 Tokunaga A, Kohyama J, Yoshida T, Nakao K, Sawamoto K, Okano H, Mapping spatio-temporal activation of Notch signaling during neurogenesis and gliogenesis in the developing mouse brain. J Neurochem. 2004 Jul;90(1):142-54
1	J:234401 Tsao PN, Matsuoka C, Wei SC, Sato A, Sato S, Hasegawa K, Chen HK, Ling TY, Mori M, Cardoso WV, Morimoto M, Epithelial Notch signaling regulates lung alveolar morphogenesis and airway epithelial integrity. Proc Natl Acad Sci U S A. 2016 Jul 19;113(29):8242-7
1	J:175037 Urbanek K, Cabral-da-Silva MC, Ide-Iwata N, Maestroni S, Delucchi F, Zheng H, Ferreira-Martins J, Ogorek B, D'Amario D, Bauer M, Zerbini G, Rota M, Hosoda T, Liao R, Anversa P, Kajstura J, Leri A, Inhibition of notch1-dependent cardiomyogenesis leads to a dilated myopathy in the neonatal heart. Circ Res. 2010 Aug 6;107(3):429-41
1	J:206321 Veniaminova NA, Vagnozzi AN, Kopinke D, Do TT, Murtaugh LC, Maillard I, Dlugosz AA, Reiter JF, Wong SY, Keratin 79 identifies a novel population of migratory epithelial cells that initiates hair canal morphogenesis and regeneration. Development. 2013 Dec;140(24):4870-80
1	J:261826 Wang Y, Wu B, Farrar E, Lui W, Lu P, Zhang D, Alfieri CM, Mao K, Chu M, Yang D, Xu D, Rauchman M, Taylor V, Conway SJ, Yutzey KE, Butcher JT, Zhou B, Notch-Tnf signalling is required for development and homeostasis of arterial valves. Eur Heart J. 2017 Mar 1;38(9):675-686
1*	J:329314 Wang Y, Yao B, Duan X, Li J, Song W, Enhejirigala, Li Z, Yuan X, Kong Y, Zhang Y, Fu X, Huang S, Notch1 down-regulation in lineage-restricted niches is involved in the development of mouse eccrine sweat glands. J Mol Histol. 2022 Oct;53(5):857-867
1	J:249938 Werth M, Schmidt-Ott KM, Leete T, Qiu A, Hinze C, Viltard M, Paragas N, Shawber CJ, Yu W, Lee P, Chen X, Sarkar A, Mu W, Rittenberg A, Lin CS, Kitajewski J, Al-Awqati Q, Barasch J, Transcription factor TFCP2L1 patterns cells in the mouse kidney collecting ducts. Elife. 2017 Jun 3;6:e24265
1	J:95110 Woods C, Montcouquiol M, Kelley MW, Math1 regulates development of the sensory epithelium in the mammalian cochlea. Nat Neurosci. 2004 Dec;7(12):1310-8
1	J:236286 Wu X, Fleming A, Ricketts T, Pavel M, Virgin H, Menzies FM, Rubinsztein DC, Autophagy regulates Notch degradation and modulates stem cell development and neurogenesis. Nat Commun. 2016 Feb 03;7:10533
1	J:175387 Wu X, Xu K, Zhang L, Deng Y, Lee P, Shapiro E, Monaco M, Makarenkova HP, Li J, Lepor H, Grishina I, Differentiation of the ductal epithelium and smooth muscle in the prostate gland are regulated by the Notch/PTEN-dependent mechanism. Dev Biol. 2011 Aug 15;356(2):337-49
1	J:251841 York JP, Ren YA, Zeng J, Bin Zhang, Wang F, Chen R, Liu J, Xia X, Zhang P, Growth Arrest Specific 2 (GAS2) is a Critical Mediator of Germ Cell Cyst Breakdown and Folliculogenesis in Mice. Sci Rep. 2016 Oct 13;6:34956