Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Fgf4  fibroblast growth factor 4   (Synonyms: Fgf-4, Fgfk, Hst1, Hstf-1, kFGF)
Results	Reference
1	J:58674 Bell SM, Schreiner CM, Scott WJ, Disrupting the establishment of polarizing activity by teratogen exposure. Mech Dev. 1999 Nov;88(2):147-57
1	J:36587 Bueno D, Skinner J, Abud H, Heath JK, Spatial and temporal relationships between Shh, Fgf4, and Fgf8 gene expression at diverse signalling centers during mouse development. Dev Dyn. 1996 Nov;207(3):291-9
1	J:343517 Christensen MM, Hallikas O, Das Roy R, Vaananen V, Stenberg OE, Hakkinen TJ, Francois JC, Asher RJ, Klein OD, Holzenberger M, Jernvall J, The developmental basis for scaling of mammalian tooth size. Proc Natl Acad Sci U S A. 2023 Jun 20;120(25):e2300374120
1	J:62029 Haraguchi R, Suzuki K, Murakami R, Sakai M, Kamikawa M, Kengaku M, Sekine K, Kawano H, Kato S, Ueno N, Yamada G, Molecular analysis of external genitalia formation: the role of fibroblast growth factor (Fgf) genes during genital tubercle formation. Development. 2000 Jun;127(11):2471-9
1	J:84077 Khokha MK, Hsu D, Brunet LJ, Dionne MS, Harland RM, Gremlin is the BMP antagonist required for maintenance of Shh and Fgf signals during limb patterning. Nat Genet. 2003 Jul;34(3):303-7
1	J:165721 Krawchuk D, Weiner SJ, Chen YT, Lu BC, Costantini F, Behringer RR, Laufer E, Twist1 activity thresholds define multiple functions in limb development. Dev Biol. 2010 Nov 1;347(1):133-46
1*	J:46971 Loomis CA, Kimmel RA, Tong CX, Michaud J, Joyner AL, Analysis of the genetic pathway leading to formation of ectopic apical ectodermal ridges in mouse Engrailed-1 mutant limbs. Development. 1998 Mar;125(6):1137-48
1	J:31829 Masuya H, Sagai T, Moriwaki K, Shiroishi T, Genetic Analysis of Mouse Mutants Affecting Limb Pattern Formation. Annu Rep Natl Inst Genet Jpn. 1994;45:52-53
1	J:90991 Michos O, Panman L, Vintersten K, Beier K, Zeller R, Zuniga A, Gremlin-mediated BMP antagonism induces the epithelial-mesenchymal feedback signaling controlling metanephric kidney and limb organogenesis. Development. 2004 Jul;131(14):3401-10
1	J:78407 O'Rourke MP, Soo K, Behringer RR, Hui CC, Tam PP, Twist plays an essential role in FGF and SHH signal transduction during mouse limb development. Dev Biol. 2002 Aug 1;248(1):143-56
1	J:19634 Rappolee DA, Basilico C, Patel Y, Werb Z, Expression and function of FGF-4 in peri-implantation development in mouse embryos. Development. 1994 Aug;120(8):2259-69
1	J:124084 Scherz PJ, McGlinn E, Nissim S, Tabin CJ, Extended exposure to Sonic hedgehog is required for patterning the posterior digits of the vertebrate limb. Dev Biol. 2007 Aug 15;308(2):343-54
1	J:52453 Sharpe J, Lettice L, Hecksher-Sorensen J, Fox M, Hill R, Krumlauf R, Identification of sonic hedgehog as a candidate gene responsible for the polydactylous mouse mutant Sasquatch. Curr Biol. 1999 Jan 28;9(2):97-100
1	J:128015 Sheth R, Bastida MF, Ros M, Hoxd and Gli3 interactions modulate digit number in the amniote limb. Dev Biol. 2007 Oct 15;310(2):430-41
1	J:78402 Sun X, Mariani FV, Martin GR, Functions of FGF signalling from the apical ectodermal ridge in limb development. Nature. 2002 Aug 1;418(6897):501-8
1	J:56002 Xu X, Weinstein M, Li C, Deng C, Fibroblast growth factor receptors (FGFRs) and their roles in limb development. Cell Tissue Res. 1999 Apr;296(1):33-43
1	J:324241 Zelarayan L, Vendrell V, Dominguez-Frutos E, Lopez-Hernandez I, Schimmang-Alonso K, Alonso MT, Alvarez Y, Maier H, Anderson MJ, Lewandoski M, Schimmang T, Inactivation of Fgf3 and Fgf4 within the Fgf3/Fgf4/Fgf15 gene cluster reveals their redundant requirement for mouse inner ear induction and embryonic survival. Dev Dyn. 2022 May;251(5):877-884
1	J:83305 Zhang Q, Murcia NS, Chittenden LR, Richards WG, Michaud EJ, Woychik RP, Yoder BK, Loss of the Tg737 protein results in skeletal patterning defects. Dev Dyn. 2003 May;227(1):78-90