Assay
Age
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RT-PCR
9.5 DPC
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Ptf1a pancreas specific transcription factor, 1a (Synonyms: bHLHa29, PTF1-p48) | |
Results | Reference |
1* | J:104894 Jacquemin P, Yoshitomi H, Kashima Y, Rousseau GG, Lemaigre FP, Zaret KS, An endothelial-mesenchymal relay pathway regulates early phases of pancreas development. Dev Biol. 2006 Feb 1;290(1):189-99 |
1 | J:195196 Lugani F, Arora R, Papeta N, Patel A, Zheng Z, Sterken R, Singer RA, Caridi G, Mendelsohn C, Sussel L, Papaioannou VE, Gharavi AG, A retrotransposon insertion in the 5' regulatory domain of Ptf1a results in ectopic gene expression and multiple congenital defects in Danforth's short tail mouse. PLoS Genet. 2013 Feb;9(2):e1003206 |
1* | J:62777 Obata J, Yano M, Mimura H, Goto T, Nakayama R, Mibu Y, Oka C, Kawaichi M, p48 subunit of mouse PTF1 binds to RBP-Jkappa/CBF-1, the intracellular mediator of Notch signalling, and is expressed in the neural tube of early stage embryos. Genes Cells. 2001 Apr;6(4):345-60 |
1 | J:195133 Semba K, Araki K, Matsumoto K, Suda H, Ando T, Sei A, Mizuta H, Takagi K, Nakahara M, Muta M, Yamada G, Nakagata N, Iida A, Ikegawa S, Nakamura Y, Araki M, Abe K, Yamamura K, Ectopic expression of Ptf1a induces spinal defects, urogenital defects, and anorectal malformations in Danforth's short tail mice. PLoS Genet. 2013 Feb;9(2):e1003204 |
1* | J:195197 Vlangos CN, Siuniak AN, Robinson D, Chinnaiyan AM, Lyons RH Jr, Cavalcoli JD, Keegan CE, Next-generation sequencing identifies the Danforth's short tail mouse mutation as a retrotransposon insertion affecting Ptf1a expression. PLoS Genet. 2013 Feb;9(2):e1003205 |
1 | J:87724 Yoshitomi H, Zaret KS, Endothelial cell interactions initiate dorsal pancreas development by selectively inducing the transcription factor Ptf1a. Development. 2004 Feb;131(4):807-17 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/21/2024 MGI 6.23 |
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