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Gene Expression Literature Summary
Assay
Age
RT-PCR
9.5 DPC

23 matching records from 23 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Tal1  T cell acute lymphocytic leukemia 1   (Synonyms: bHLHa17, Hpt, Scl, SCL/tal-1)
Results  Reference
1*J:85729 Alvarez-Silva M, Belo-Diabangouaya P, Salaun J, Dieterlen-Lievre F, Mouse placenta is a major hematopoietic organ. Development. 2003 Nov;130(22):5437-44
1J:188652 Borges L, Iacovino M, Mayerhofer T, Koyano-Nakagawa N, Baik J, Garry DJ, Kyba M, Letarte M, Perlingeiro RC, A critical role for endoglin in the emergence of blood during embryonic development. Blood. 2012 Jun 7;119(23):5417-28
1J:239299 Brooke-Bisschop T, Savory JG, Foley T, Ringuette R, Lohnes D, Essential roles for Cdx in murine primitive hematopoiesis. Dev Biol. 2017 Feb 15;422(2):115-124
1*J:229936 Cano E, Carmona R, Ruiz-Villalba A, Rojas A, Chau YY, Wagner KD, Wagner N, Hastie ND, Munoz-Chapuli R, Perez-Pomares JM, Extracardiac septum transversum/proepicardial endothelial cells pattern embryonic coronary arterio-venous connections. Proc Natl Acad Sci U S A. 2016 Jan 19;113(3):656-61
1*J:261784 Chennupati V, Veiga DF, Maslowski KM, Andina N, Tardivel A, Yu EC, Stilinovic M, Simillion C, Duchosal MA, Quadroni M, Roberts I, Sankaran VG, MacDonald HR, Fasel N, Angelillo-Scherrer A, Schneider P, Hoang T, Allam R, Ribonuclease inhibitor 1 regulates erythropoiesis by controlling GATA1 translation. J Clin Invest. 2018 Apr 2;128(4):1597-1614
1*J:266594 Chiu SK, Saw J, Huang Y, Sonderegger SE, Wong NC, Powell DR, Beck D, Pimanda JE, Tremblay CS, Curtis DJ, A novel role for Lyl1 in primitive erythropoiesis. Development. 2018 Oct 11;145(19):dev162990
1J:140201 Goldie LC, Lucitti JL, Dickinson ME, Hirschi KK, Cell signaling directing the formation and function of hemogenic endothelium during murine embryogenesis. Blood. 2008 Oct 15;112(8):3194-204
1J:210754 Lan Y, He W, Li Z, Wang Y, Wang J, Gao J, Wang W, Cheng T, Liu B, Yang X, Endothelial Smad4 restrains the transition to hematopoietic progenitors via suppression of ERK activation. Blood. 2014 Apr 3;123(14):2161-71
1*J:222868 Liu F, Li D, Yu YY, Kang I, Cha MJ, Kim JY, Park C, Watson DK, Wang T, Choi K, Induction of hematopoietic and endothelial cell program orchestrated by ETS transcription factor ER71/ETV2. EMBO Rep. 2015 May;16(5):654-69
1J:122926 Matsumoto N, Kubo A, Liu H, Akita K, Laub F, Ramirez F, Keller G, Friedman SL, Developmental regulation of yolk sac hematopoiesis by Kruppel-like factor 6. Blood. 2006 Feb 15;107(4):1357-65
1*J:50937 Okada H, Watanabe T, Niki M, Takano H, Chiba N, Yanai N, Tani K, Hibino H, Asano S, Mucenski ML, Ito Y, Noda T, Satake M, AML1(-/-) embryos do not express certain hematopoiesis-related gene transcripts including those of the PU.1 gene. Oncogene. 1998 Nov 5;17(18):2287-93
1*J:41559 Palis J, Robertson S, Kennedy M, Wall C, Keller G, Development of erythroid and myeloid progenitors in the yolk sac and embryo proper of the mouse. Development. 1999 Nov;126(22):5073-84
1*J:130143 Redmond LC, Dumur CI, Archer KJ, Haar JL, Lloyd JA, Identification of erythroid-enriched gene expression in the mouse embryonic yolk sac using microdissected cells. Dev Dyn. 2008 Feb;237(2):436-46
1*J:27458 Robb L, Lyons I, Li R, Hartley L, Kontgen F, Harvey RP, Metcalf D, Begley CG, Absence of yolk sac hematopoiesis from mice with a targeted disruption of the scl gene. Proc Natl Acad Sci U S A. 1995 Jul 18;92(15):7075-9
1J:97176 Robert-Moreno A, Espinosa L, de la Pompa JL, Bigas A, RBPj{kappa}-dependent Notch function regulates Gata2 and is essential for the formation of intra-embryonic hematopoietic cells. Development. 2005 Mar;132(5):1117-26
1J:123174 Robert-Moreno A, Espinosa L, Sanchez MJ, de la Pompa JL, Bigas A, The notch pathway positively regulates programmed cell death during erythroid differentiation. Leukemia. 2007 Jul;21(7):1496-503
1*J:23061 Shivdasani RA, Mayer EL, Orkin SH, Absence of blood formation in mice lacking the T-cell leukaemia oncoprotein tal-1/SCL. Nature. 1995 Feb 2;373(6513):432-4
1J:326086 Sinha T, Lammerts van Bueren K, Dickel DE, Zlatanova I, Thomas R, Lizama CO, Xu SM, Zovein AC, Ikegami K, Moskowitz IP, Pollard KS, Pennacchio LA, Black BL, Differential Etv2 threshold requirement for endothelial and erythropoietic development. Cell Rep. 2022 May 31;39(9):110881
1*J:203178 Spensberger D, Kotsopoulou E, Ferreira R, Broccardo C, Scott LM, Fourouclas N, Ottersbach K, Green AR, Gottgens B, Deletion of the Scl +19 enhancer increases the blood stem cell compartment without affecting the formation of mature blood lineages. Exp Hematol. 2012 Jul;40(7):588-598.e1
1J:187883 Van Handel B, Montel-Hagen A, Sasidharan R, Nakano H, Ferrari R, Boogerd CJ, Schredelseker J, Wang Y, Hunter S, Org T, Zhou J, Li X, Pellegrini M, Chen JN, Orkin SH, Kurdistani SK, Evans SM, Nakano A, Mikkola HK, Scl represses cardiomyogenesis in prospective hemogenic endothelium and endocardium. Cell. 2012 Aug 3;150(3):590-605
1J:46127 Visvader JE, Fujiwara Y, Orkin SH, Unsuspected role for the T-cell leukemia protein SCL/tal-1 in vascular development. Genes Dev. 1998 Feb 15;12(4):473-9
1J:87724 Yoshitomi H, Zaret KS, Endothelial cell interactions initiate dorsal pancreas development by selectively inducing the transcription factor Ptf1a. Development. 2004 Feb;131(4):807-17
1J:99332 Yuasa H, Oike Y, Iwama A, Nishikata I, Sugiyama D, Perkins A, Mucenski ML, Suda T, Morishita K, Oncogenic transcription factor Evi1 regulates hematopoietic stem cell proliferation through GATA-2 expression. EMBO J. 2005 Jun 1;24(11):1976-87

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory