Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Hoxb8  homeobox B8   (Synonyms: Hox-2.4)
Results	Reference
1	J:81154 Agarwal P, Wylie JN, Galceran J, Arkhitko O, Li C, Deng C, Grosschedl R, Bruneau BG, Tbx5 is essential for forelimb bud initiation following patterning of the limb field in the mouse embryo. Development. 2003 Feb;130(3):623-33
1*	J:27786 Chan DC, Laufer E, Tabin C, Leder P, Polydactylous limbs in Strong's Luxoid mice result from ectopic polarizing activity. Development. 1995 Jul;121(7):1971-8
1*	J:19897 Charite J, de Graaff W, Shen S, Deschamps J, Ectopic expression of Hoxb-8 causes duplication of the ZPA in the forelimb and homeotic transformation of axial structures. Cell. 1994 Aug 26;78(4):589-601
1	J:139339 Chawengsaksophak K, de Graaff W, Rossant J, Deschamps J, Beck F, Cdx2 is essential for axial elongation in mouse development. Proc Natl Acad Sci U S A. 2004 May 18;101(20):7641-5
1*	J:114714 DeLaurier A, Schweitzer R, Logan M, Pitx1 determines the morphology of muscle, tendon, and bones of the hindlimb. Dev Biol. 2006 Nov 1;299(1):22-34
1	J:100027 Isono K, Fujimura Y, Shinga J, Yamaki M, O-Wang J, Takihara Y, Murahashi Y, Takada Y, Mizutani-Koseki Y, Koseki H, Mammalian polyhomeotic homologues phc2 and phc1 act in synergy to mediate polycomb repression of hox genes. Mol Cell Biol. 2005 Aug;25(15):6694-706
1*	J:85471 Juan AH, Ruddle FH, Enhancer timing of Hox gene expression: deletion of the endogenous Hoxc8 early enhancer. Development. 2003 Oct;130(20):4823-34
1*	J:86684 Medina-Martinez O, Ramirez-Solis R, In vivo mutagenesis of the Hoxb8 hexapeptide domain leads to dominant homeotic transformations that mimic the loss-of-function mutations in genes of the Hoxb cluster. Dev Biol. 2003 Dec 1;264(1):77-90
1*	J:89166 Oosterveen T, Meijlink F, Deschamps J, Expression of retinaldehyde dehydrogenase II and sequential activation of 5' Hoxb genes in the mouse caudal hindbrain. Gene Expr Patterns. 2004 May;4(3):243-7
1	J:77675 te Welscher P, Fernandez-Teran M, Ros MA, Zeller R, Mutual genetic antagonism involving GLI3 and dHAND prepatterns the vertebrate limb bud mesenchyme prior to SHH signaling. Genes Dev. 2002 Feb 15;16(4):421-6
1*	J:68720 van den Akker E, Fromental-Ramain C, de Graaff W, Le Mouellic H, Brulet P, Chambon P, Deschamps J, Axial skeletal patterning in mice lacking all paralogous group 8 Hox genes. Development. 2001 May;128(10):1911-21
1	J:226712 Wong SF, Agarwal V, Mansfield JH, Denans N, Schwartz MG, Prosser HM, Pourquie O, Bartel DP, Tabin CJ, McGlinn E, Independent regulation of vertebral number and vertebral identity by microRNA-196 paralogs. Proc Natl Acad Sci U S A. 2015 Sep 1;112(35):E4884-93
1*	J:156017 Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S, Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N, Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y, Okado H, Hashimoto M, Asahara H, A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Dev Cell. 2009 Dec;17(6):836-48
1	J:154781 Young T, Rowland JE, van de Ven C, Bialecka M, Novoa A, Carapuco M, van Nes J, de Graaff W, Duluc I, Freund JN, Beck F, Mallo M, Deschamps J, Cdx and Hox genes differentially regulate posterior axial growth in mammalian embryos. Dev Cell. 2009 Oct;17(4):516-26
1	J:150673 Zhao X, Sirbu IO, Mic FA, Molotkova N, Molotkov A, Kumar S, Duester G, Retinoic acid promotes limb induction through effects on body axis extension but is unnecessary for limb patterning. Curr Biol. 2009 Jun 23;19(12):1050-7
1*	J:49322 Zuniga A, Zeller R, Gli3 (Xt) and formin (ld) participate in the positioning of the polarising region and control of posterior limb-bud identity. Development. 1999 Jan;126(1):13-21