Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Hes5  hes family bHLH transcription factor 5   (Synonyms: bHLHb38)
Results	Reference
1*	J:102528 Barsi JC, Rajendra R, Wu JI, Artzt K, Mind bomb1 is a ubiquitin ligase essential for mouse embryonic development and Notch signaling. Mech Dev. 2005 Oct;122(10):1106-17
1*	J:105958 Chen J, Lu L, Shi S, Stanley P, Expression of Notch signaling pathway genes in mouse embryos lacking beta4galactosyltransferase-1. Gene Expr Patterns. 2006 Apr;6(4):376-82
1*	J:88580 Cordes R, Schuster-Gossler K, Serth K, Gossler A, Specification of vertebral identity is coupled to Notch signalling and the segmentation clock. Development. 2004 Mar;131(6):1221-33
1*	J:206224 Dixit R, Tachibana N, Touahri Y, Zinyk D, Logan C, Schuurmans C, Gene expression is dynamically regulated in retinal progenitor cells prior to and during overt cellular differentiation. Gene Expr Patterns. 2014 Jan;14(1):42-54
1	J:48859 Evrard YA, Lun Y, Aulehla A, Gan L, Johnson RL, lunatic fringe is an essential mediator of somite segmentation and patterning. Nature. 1998 Jul 23;394(6691):377-81
1*	J:316299 Freire AG, Waghray A, Soares-da-Silva F, Resende TP, Lee DF, Pereira CF, Nascimento DS, Lemischka IR, Pinto-do-O P, Transient HES5 Activity Instructs Mesodermal Cells toward a Cardiac Fate. Stem Cell Reports. 2017 Jul 11;9(1):136-148
1*	J:136658 Ge C, Liu T, Hou X, Stanley P, In vivo consequences of deleting EGF repeats 8-12 including the ligand binding domain of mouse Notch1. BMC Dev Biol. 2008;8:48
1*	J:55841 Hamada Y, Kadokawa Y, Okabe M, Ikawa M, Coleman JR, Tsujimoto Y, Mutation in ankyrin repeats of the mouse Notch2 gene induces early embryonic lethality. Development. 1999 Aug;126(15):3415-24
1	J:94391 Hatakeyama J, Bessho Y, Katoh K, Ookawara S, Fujioka M, Guillemot F, Kageyama R, Hes genes regulate size, shape and histogenesis of the nervous system by control of the timing of neural stem cell differentiation. Development. 2004 Nov;131(22):5539-50
1*	J:278751 Hatakeyama J, Sakamoto S, Kageyama R, Hes1 and Hes5 regulate the development of the cranial and spinal nerve systems. Dev Neurosci. 2006;28(1-2):92-101
1	J:175891 Hitoshi S, Ishino Y, Kumar A, Jasmine S, Tanaka KF, Kondo T, Kato S, Hosoya T, Hotta Y, Ikenaka K, Mammalian Gcm genes induce Hes5 expression by active DNA demethylation and induce neural stem cells. Nat Neurosci. 2011 Aug;14(8):957-64
1	J:232516 Parchem RJ, Moore N, Fish JL, Parchem JG, Braga TT, Shenoy A, Oldham MC, Rubenstein JL, Schneider RA, Blelloch R, miR-302 Is Required for Timing of Neural Differentiation, Neural Tube Closure, and Embryonic Viability. Cell Rep. 2015 Aug 4;12(5):760-73
1	J:92098 Petersen PH, Zou K, Krauss S, Zhong W, Continuing role for mouse Numb and Numbl in maintaining progenitor cells during cortical neurogenesis. Nat Neurosci. 2004 Aug;7(8):803-11
1	J:282947 Poncet N, Halley PA, Lipina C, Gierlinski M, Dady A, Singer GA, Febrer M, Shi YB, Yamaguchi TP, Taylor PM, Storey KG, Wnt regulates amino acid transporter Slc7a5 and so constrains the integrated stress response in mouse embryos. EMBO Rep. 2020 Jan 7;21(1):e48469
1	J:104523 Ribes V, Wang Z, Dolle P, Niederreither K, Retinaldehyde dehydrogenase 2 (RALDH2)-mediated retinoic acid synthesis regulates early mouse embryonic forebrain development by controlling FGF and sonic hedgehog signaling. Development. 2006 Jan;133(2):351-61
1	J:198880 Shi M, Hu ZL, Zheng MH, Song NN, Huang Y, Zhao G, Han H, Ding YQ, Notch-Rbpj signaling is required for the development of noradrenergic neurons in the mouse locus coeruleus. J Cell Sci. 2012 Sep 15;125(Pt 18):4320-32
1*	J:209112 Shimizu H, Kubo A, Uchibe K, Hashimoto M, Yokoyama S, Takada S, Mitsuoka K, Asahara H, The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo. PLoS One. 2013;8(10):e75754
1	J:59271 Yamaguchi TP, Takada S, Yoshikawa Y, Wu N, McMahon AP, T (Brachyury) is a direct target of Wnt3a during paraxial mesoderm specification. Genes Dev. 1999 Dec 15;13(24):3185-90
1*	J:156017 Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S, Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N, Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y, Okado H, Hashimoto M, Asahara H, A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Dev Cell. 2009 Dec;17(6):836-48