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Gene Expression Literature Summary
Assay
Age
In situ RNA (whole mount)
9.5 DPC

8 matching records from 8 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Noto  notochord homeobox   (Synonyms: Flh, MmNot, Not, tc)
Results  Reference
1*J:91405 Abdelkhalek HB, Beckers A, Schuster-Gossler K, Pavlova MN, Burkhardt H, Lickert H, Rossant J, Reinhardt R, Schalkwyk LC, Muller I, Herrmann BG, Ceolin M, Rivera-Pomar R, Gossler A, The mouse homeobox gene Not is required for caudal notochord development and affected by the truncate mutation. Genes Dev. 2004 Jul 15;18(14):1725-36
1J:254597 Bhargava S, Cox B, Polydorou C, Gresakova V, Korinek V, Strnad H, Sedlacek R, Epp TA, Chawengsaksophak K, The epigenetic modifier Fam208a is required to maintain epiblast cell fitness. Sci Rep. 2017 Aug 24;7(1):9322
1J:294824 Dias A, Lozovska A, Wymeersch FJ, Novoa A, Binagui-Casas A, Sobral D, Martins GG, Wilson V, Mallo M, A Tgfbr1/Snai1-dependent developmental module at the core of vertebrate axial elongation. Elife. 2020 Jun 29;9:e56615
1J:301045 Guo SS, Au TYK, Wynn S, Aszodi A, Chan D, Fassler R, Cheah KSE, beta1 Integrin regulates convergent extension in mouse notogenesis, ensures notochord integrity and the morphogenesis of vertebrae and intervertebral discs. Development. 2020 Nov 18;147(22):dev192724
1J:195910 Maier JA, Lo Y, Harfe BD, Foxa1 and Foxa2 are required for formation of the intervertebral discs. PLoS One. 2013;8(1):e55528
1*J:330741 Orchard P, White JS, Thomas PE, Mychalowych A, Kiseleva A, Hensley J, Allen B, Parker SCJ, Keegan CE, Genome-wide chromatin accessibility and transcriptome profiling show minimal epigenome changes and coordinated transcriptional dysregulation of hedgehog signaling in Danforth's short tail mice. Hum Mol Genet. 2019 Mar 1;28(5):736-750
1*J:93513 Plouhinec JL, Granier C, Le Mentec C, Lawson KA, Saberan-Djoneidi D, Aghion J, Shi DL, Collignon J, Mazan S, Identification of the mammalian Not gene via a phylogenomic approach. Gene Expr Patterns. 2004 Nov;5(1):11-22
1*J:153634 Ukita K, Hirahara S, Oshima N, Imuta Y, Yoshimoto A, Jang CW, Oginuma M, Saga Y, Behringer RR, Kondoh H, Sasaki H, Wnt signaling maintains the notochord fate for progenitor cells and supports the posterior extension of the notochord. Mech Dev. 2009 Oct;126(10):791-803

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory