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Gene Expression Literature Summary
Assay
Age
In situ RNA (section)
9.5 DPC

14 matching records from 14 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Gbx2  gastrulation brain homeobox 2   (Synonyms: Gbx-2, MMoxA, Stra7)
Results  Reference
1J:100584 Byrd NA, Meyers EN, Loss of Gbx2 results in neural crest cell patterning and pharyngeal arch artery defects in the mouse embryo. Dev Biol. 2005 Aug 1;284(1):233-45
1J:152319 Calmont A, Ivins S, Van Bueren KL, Papangeli I, Kyriakopoulou V, Andrews WD, Martin JF, Moon AM, Illingworth EA, Basson MA, Scambler PJ, Tbx1 controls cardiac neural crest cell migration during arch artery development by regulating Gbx2 expression in the pharyngeal ectoderm. Development. 2009 Sep;136(18):3173-83
1J:108511 Griesel G, Treichel D, Collombat P, Krull J, Zembrzycki A, van den Akker WM, Gruss P, Simeone A, Mansouri A, Sp8 controls the anteroposterior patterning at the midbrain-hindbrain border. Development. 2006 May;133(9):1779-87
1J:128377 Hatch EP, Noyes CA, Wang X, Wright TJ, Mansour SL, Fgf3 is required for dorsal patterning and morphogenesis of the inner ear epithelium. Development. 2007 Oct;134(20):3615-25
1J:101263 Ivins S, Lammerts van Beuren K, Roberts C, James C, Lindsay E, Baldini A, Ataliotis P, Scambler PJ, Microarray analysis detects differentially expressed genes in the pharyngeal region of mice lacking Tbx1. Dev Biol. 2005 Sep 15;285(2):554-69
1J:96329 Ladher RK, Wright TJ, Moon AM, Mansour SL, Schoenwolf GC, FGF8 initiates inner ear induction in chick and mouse. Genes Dev. 2005 Mar 1;19(5):603-13
1*J:58078 Liu A, Losos K, Joyner AL, FGF8 can activate Gbx2 and transform regions of the rostral mouse brain into a hindbrain fate. Development. 1999 Nov;126(21):4827-38
1*J:105983 Ohyama T, Mohamed OA, Taketo MM, Dufort D, Groves AK, Wnt signals mediate a fate decision between otic placode and epidermis. Development. 2006 Mar;133(5):865-75
1J:188279 Peng C, Li N, Ng YK, Zhang J, Meier F, Theis FJ, Merkenschlager M, Chen W, Wurst W, Prakash N, A Unilateral Negative Feedback Loop Between miR-200 microRNAs and Sox2/E2F3 Controls Neural Progenitor Cell-Cycle Exit and Differentiation. J Neurosci. 2012 Sep 19;32(38):13292-13308
1J:284143 Phillips HM, Stothard CA, Shaikh Qureshi WM, Kousa AI, Briones-Leon JA, Khasawneh RR, O'Loughlin C, Sanders R, Mazzotta S, Dodds R, Seidel K, Bates T, Nakatomi M, Cockell SJ, Schneider JE, Mohun TJ, Maehr R, Kist R, Peters H, Bamforth SD, Pax9 is required for cardiovascular development and interacts with Tbx1 in the pharyngeal endoderm to control 4th pharyngeal arch artery morphogenesis. Development. 2019 Sep 23;146(18):dev177618
1J:212428 Raft S, Andrade LR, Shao D, Akiyama H, Henkemeyer M, Wu DK, Ephrin-B2 governs morphogenesis of endolymphatic sac and duct epithelia in the mouse inner ear. Dev Biol. 2014 Jun 1;390(1):51-67
1J:114449 Robledo RF, Lufkin T, Dlx5 and Dlx6 homeobox genes are required for specification of the mammalian vestibular apparatus. Genesis. 2006 Sep;44(9):425-37
1J:195357 Roeseler DA, Sachdev S, Buckley DM, Joshi T, Wu DK, Xu D, Hannink M, Waters ST, Elongation factor 1 alpha1 and genes associated with Usher syndromes are downstream targets of GBX2. PLoS One. 2012;7(11):e47366
1J:320909 Stothard CA, Mazzotta S, Vyas A, Schneider JE, Mohun TJ, Henderson DJ, Phillips HM, Bamforth SD, Pax9 and Gbx2 Interact in the Pharyngeal Endoderm to Control Cardiovascular Development. J Cardiovasc Dev Dis. 2020 May 25;7(2):20

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory