Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Ascl2  achaete-scute family bHLH transcription factor 2   (Synonyms: 2410083I15Rik, bHLHa45, Mash2)
Results	Reference
1	J:112884 Arima T, Hata K, Tanaka S, Kusumi M, Li E, Kato K, Shiota K, Sasaki H, Wake N, Loss of the maternal imprint in Dnmt3Lmat-/- mice leads to a differentiation defect in the extraembryonic tissue. Dev Biol. 2006 Sep 15;297(2):361-73
1	J:314901 Bao H, Liu D, Xu Y, Sun Y, Mu C, Yu Y, Wang C, Han Q, Liu S, Cai H, Liu F, Kong S, Deng W, Cao B, Wang H, Wang Q, Lu J, Hyperactivated Wnt-beta-catenin signaling in the absence of sFRP1 and sFRP5 disrupts trophoblast differentiation through repression of Ascl2. BMC Biol. 2020 Oct 27;18(1):151
1	J:64703 Cocchia M, Huber R, Pantano S, Chen EY, Ma P, Forabosco A, Ko MS, Schlessinger D, PLAC1, an Xq26 gene with placenta-specific expression. Genomics. 2000 Sep 15;68(3):305-12
1	J:214531 Du X, Dong Y, Shi H, Li J, Kong S, Shi D, Sun LV, Xu T, Deng K, Tao W, Mst1 and mst2 are essential regulators of trophoblast differentiation and placenta morphogenesis. PLoS One. 2014;9(3):e90701
1*	J:23260 Guillemot F, Caspary T, Tilghman SM, Copeland NG, Gilbert DJ, Jenkins NA, Anderson DJ, Joyner AL, Rossant J, Nagy A, Genomic imprinting of Mash2, a mouse gene required for trophoblast development. Nat Genet. 1995 Mar;9(3):235-42
1*	J:192195 Himes KP, Koppes E, Chaillet JR, Generalized disruption of inherited genomic imprints leads to wide-ranging placental defects and dysregulated fetal growth. Dev Biol. 2013 Jan 1;373(1):72-82
1	J:202357 Hu D, Scott IC, Snider F, Geary-Joo C, Zhao X, Simmons DG, Cross JC, The basic helix-loop-helix transcription factor Hand1 regulates mouse development as a homodimer. Dev Biol. 2013 Oct 15;382(2):470-81
1*	J:53186 Kato Y, Rideout WM 3rd, Hilton K, Barton SC, Tsunoda Y, Surani MA, Developmental potential of mouse primordial germ cells. Development. 1999 May;126(9):1823-32
1*	J:80175 Kuang SQ, Liao L, Zhang H, Pereira FA, Yuan Y, DeMayo FJ, Ko L, Xu J, Deletion of the Cancer-amplified Coactivator AIB3 Results in Defective Placentation and Embryonic Lethality. J Biol Chem. 2002 Nov 22;277(47):45356-60
1*	J:42488 Luo J, Sladek R, Bader JA, Matthyssen A, Rossant J, Giguere V, Placental abnormalities in mouse embryos lacking the orphan nuclear receptor ERR-beta. Nature. 1997 Aug 21;388(6644):778-82
1*	J:30829 McLaughlin KJ, Szabo P, Haegel H, Mann JR, Mouse embryos with paternal duplication of an imprinted chromosome 7 region die at midgestation and lack placental spongiotrophoblast. Development. 1996 Jan;122(1):265-70
1*	J:52247 Morasso MI, Grinberg A, Robinson G, Sargent TD, Mahon KA, Placental failure in mice lacking the homeobox gene Dlx3. Proc Natl Acad Sci U S A. 1999 Jan 5;96(1):162-7
1*	J:87675 Moser M, Li Y, Vaupel K, Kretzschmar D, Kluge R, Glynn P, Buettner R, Placental failure and impaired vasculogenesis result in embryonic lethality for neuropathy target esterase-deficient mice. Mol Cell Biol. 2004 Feb;24(4):1667-79
1	J:107381 Nadra K, Anghel SI, Joye E, Tan NS, Basu-Modak S, Trono D, Wahli W, Desvergne B, Differentiation of trophoblast giant cells and their metabolic functions are dependent on peroxisome proliferator-activated receptor beta/delta. Mol Cell Biol. 2006 Apr;26(8):3266-81
1	J:170637 Oh-McGinnis R, Bogutz AB, Lefebvre L, Partial loss of Ascl2 function affects all three layers of the mature placenta and causes intrauterine growth restriction. Dev Biol. 2011 Mar 15;351(2):277-86
1	J:236405 Uchida K, Nakazawa M, Yamagishi C, Mikoshiba K, Yamagishi H, Type 1 and 3 inositol trisphosphate receptors are required for extra-embryonic vascular development. Dev Biol. 2016 Oct 1;418(1):89-97
1	J:104372 van Nes J, de Graaff W, Lebrin F, Gerhard M, Beck F, Deschamps J, The Cdx4 mutation affects axial development and reveals an essential role of Cdx genes in the ontogenesis of the placental labyrinth in mice. Development. 2006 Feb;133(3):419-28
1*	J:167034 Wansleeben C, Feitsma H, Tertoolen L, Kroon C, Guryev V, Cuppen E, Meijlink F, A novel mutant allele of Ncx1: a single amino acid substitution leads to cardiac dysfunction. Int J Dev Biol. 2010;54(10):1465-71
1*	J:52278 Wendling O, Chambon P, Mark M, Retinoid X receptors are essential for early mouse development and placentogenesis. Proc Natl Acad Sci U S A. 1999 Jan 19;96(2):547-51