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Gene Expression Literature Summary
Assay
Age
In situ RNA (whole mount)
8.5 DPC

20 matching records from 20 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Notch1  notch 1   (Synonyms: 9930111A19Rik, lin-12, Mis6, Motch A, N1, Tan1)
Results  Reference
1*J:54606 Barrantes IB, Elia AJ, Wunsch K, De Angelis MH, Mak TW, Rossant J, Conlon RA, Gossler A, de la Pompa JL, Interaction between Notch signalling and Lunatic fringe during somite boundary formation in the mouse. Curr Biol. 1999 May 6;9(9):470-80
1J:205649 Chalamalasetty RB, Dunty WC Jr, Biris KK, Ajima R, Iacovino M, Beisaw A, Feigenbaum L, Chapman DL, Yoon JK, Kyba M, Yamaguchi TP, The Wnt3a/beta-catenin target gene Mesogenin1 controls the segmentation clock by activating a Notch signalling program. Nat Commun. 2011;2:390
1*J:242897 Chiang IK, Fritzsche M, Pichol-Thievend C, Neal A, Holmes K, Lagendijk A, Overman J, D'Angelo D, Omini A, Hermkens D, Lesieur E, Liu K, Ratnayaka I, Corada M, Bou-Gharios G, Carroll J, Dejana E, Schulte-Merker S, Hogan B, Beltrame M, De Val S, Francois M, SoxF factors induce Notch1 expression via direct transcriptional regulation during early arterial development. Development. 2017 Jul 15;144(14):2629-2639
1J:174608 Chong DC, Koo Y, Xu K, Fu S, Cleaver O, Stepwise arteriovenous fate acquisition during mammalian vasculogenesis. Dev Dyn. 2011 Sep;240(9):2153-65
1*J:25248 Conlon RA, Reaume AG, Rossant J, Notch1 is required for the coordinate segmentation of somites. Development. 1995 May;121(5):1533-45
1*J:45340 Friedrich GA, Hildebrand JD, Soriano P, The secretory protein Sec8 is required for paraxial mesoderm formation in the mouse. Dev Biol. 1997 Dec 15;192(2):364-74
1J:36210 Georges-Labouesse EN, George EL, Rayburn H, Hynes RO, Mesodermal development in mouse embryos mutant for fibronectin. Dev Dyn. 1996 Oct;207(2):145-56
1*J:44237 Goh KL, Yang JT, Hynes RO, Mesodermal defects and cranial neural crest apoptosis in alpha5 integrin-null embryos. Development. 1997 Nov;124(21):4309-19
1*J:47700 Greene ND, Gerrelli D, Van Straaten HW, Copp AJ, Abnormalities of floor plate, notochord and somite differentiation in the loop-tail (Lp) mouse: a model of severe neural tube defects. Mech Dev. 1998 Apr;73(1):59-72
1J:79834 Hamblet NS, Lijam N, Ruiz-Lozano P, Wang J, Yang Y, Luo Z, Mei L, Chien KR, Sussman DJ, Wynshaw-Boris A, Dishevelled 2 is essential for cardiac outflow tract development, somite segmentation and neural tube closure. Development. 2002 Dec;129(24):5827-38
1*J:35621 Koop KE, MacDonald LM, Lobe CG, Transcripts of Grg4, a murine groucho-related gene, are detected in adjacent tissues to other murine neurogenic gene homologues during embryonic development. Mech Dev. 1996 Sep;59(1):73-87
1*J:20157 Kopan R, Nye JS, Weintraub H, The intracellular domain of mouse Notch: a constitutively activated repressor of myogenesis directed at the basic helix-loop-helix region of MyoD. Development. 1994 Sep;120(9):2385-96
1J:170405 Kueh AJ, Dixon MP, Voss AK, Thomas T, HBO1 is required for H3K14 acetylation and normal transcriptional activity during embryonic development. Mol Cell Biol. 2011 Feb;31(4):845-60
1*J:185804 Larkins CE, Long AB, Caspary T, Defective Nodal and Cerl2 expression in the Arl13b(hnn) mutant node underlie its heterotaxia. Dev Biol. 2012 Jul 1;367(1):15-24
1*J:3293 Reaume AG, Conlon RA, Zirngibl R, Yamaguchi TP, Rossant J, Expression analysis of a Notch homologue in the mouse embryo. Dev Biol. 1992 Dec;154(2):377-87
1J:83299 Shi S, Stanley P, Protein O-fucosyltransferase 1 is an essential component of Notch signaling pathways. Proc Natl Acad Sci U S A. 2003 Apr 29;100(9):5234-9
1J:17509 Swiatek PJ, Lindsell CE, del Amo FF, Weinmaster G, Gridley T, Notch1 is essential for postimplantation development in mice. Genes Dev. 1994 Mar 15;8(6):707-19
1J:87765 Timmerman LA, Grego-Bessa J, Raya A, Bertran E, Perez-Pomares JM, Diez J, Aranda S, Palomo S, McCormick F, Izpisua-Belmonte JC, de la Pompa JL, Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation. Genes Dev. 2004 Jan 1;18(1):99-115
1J:108444 Watanabe Y, Kokubo H, Miyagawa-Tomita S, Endo M, Igarashi K, Aisaki KI, Kanno J, Saga Y, Activation of Notch1 signaling in cardiogenic mesoderm induces abnormal heart morphogenesis in mouse. Development. 2006 May;133(9):1625-34
1J:40308 Wong PC, Zheng H, Chen H, Becher MW, Sirinathsinghji DJ, Trumbauer ME , Chen HY , Price DL , Van der Ploeg LH , Sisodia SS, Presenilin 1 is required for Notch1 and DII1 expression in the paraxial mesoderm. Nature. 1997 May 15;387(6630):288-92

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory